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| 1 | Risk-adjustment in hepatobiliarypancreatic surgery显示文摘AIM: The present study evaluates the performance of the POSSUM, the American Society of Anesthetists (ASA),APACHE and Childs classification in predicting mortality and morbidity in hepatopancreaticobiliary (HPB) surgery.We describe especially the limitations and advantages of risk in stratifying the patients.METHODS: We investigated 177 randomly chosen patients undergoing eledive complex HPB surgery in a single institution with a total of 71 pre-operative and intra-operative risk factors.Primary endpoint was in-hospital mortality and morbidity.Ordered logistic regression analysis was used to identify individual predictors of operative morbidity and mortality.RESULTS: The operative mortality in the series was 3.95% .This compared well with the p-POSSUM and APACHE predicted mortality of 4.31% and 4.29% respectively. Postoperative complications amounted to 45% with 24 (13.6%)patients having a major adverse event. On multivariate analysis the pre-operative POSSUM physiological score (OR = 1.18,P = 0.009) was superior in predicting complications compared to the ASA (P = 0.108), APACHE (P = 0.117)or Childs classification (P = 0.136). In addition, serum sodium, creatinine, international normalized ratio (INR),pulse rate, and intra-operative blood loss were independent risk factors. A combination of the POSSUM variables and INR offered the optimal combination of risk factors for risk prognostication in HPB surgery.CONCLUSION: Morbidity for elective HPB surgery can be accurately predicted and applied in everyday surgical practice as an adjunct in the process of informed consent and for effective allocation of resources for intensive and high-dependency care facilities. | Hemant M Kocher Paris P Tekkis Palepu Gopal Ameet G Patel Simon Cottam Irving S Benjamin | 2005 | World Journal of Gastroenterology2005，11，16： | 3 |
| 2 | A double-blind study of paliperidone palmitaite and risperidone long-acting injectable in adults with schizophrenia 显示文摘 | Pandina G Lane R Gopal S | 2011 | Prog Neuropsycopharmacol Biol Psychiatry2011，35，1： | 1 |
| 3 | International Software Piracy: Analysis of key issues and impacts显示文摘 | Gopal R D Sanders G L | 1998 | Information Systems Research1998，9，4： | 1 |
| 4 | Radicular Cyst Associated With an Endodontically Treated Deciduous Molar: A Case 显示文摘 | Suchitra G Bhagirathi DL Kango Prasad Gopal | 2012 | International Journal of Oral & Maxillo- facial Pathology2012，3，2： | 1 |
| 5 | Effectiveness of short- term, enhanced, infection control support in improving com- pliance with infection control guidelines and practice in nurs- ing homes: a cluster randomized trial显示文摘 | Gopal Rao G Jeanes A Russell H | 2009 | Epidemiology and Infection2009，137，10： | 1 |
| 6 | Pt/H-ZSM-12 as a catalyst for the hydroisomerization of C5-C7 n-alkanes and simultaneous saturation of benzene显示文摘 | Panagiotis G Smirniotis | 2003 | Appl Catal A:2003，247，1： | 1 |
| 7 | Direct conversion of starch to L (+)lactic acid by amylase producing lactobacillus amylophilus GV6显示文摘 | Vishnu C G Seenayya Gopal Reddy | 2000 | Bioprocess Engineering2000，23，： | 1 |
| 8 | An investigation on glycerol biosynthesis by an osmophilie yeast in a bioreaetor 显示文摘 | Sahoo D K Gopal P Agarwal G P | 2001 | Process Biochemistry2001，，36： | 1 |
| 9 | A neural network method for efficient vegetation mapping显示文摘 | Carpenter G A Gopal S Macomber S | 1999 | Remote Sensing of Environment1999，70，3： | 1 |
| 10 | Tungsten heavy alloy for defence applications显示文摘 | ARORA A GOPAL R V G | 2004 | Materials Technology2004，19，4： | 1 |
| 11 | MIR-451 and Ima- tinibmesylate inhibit tumor growth of Glioblastoma stem cells显示文摘 | Hilah G Gopal P Andrew A | 2008 | Biochem Biophys Res Commun2008，8，31： | 1 |
| 12 | Identification and validation of genes involved in gastric tumorigenesis 显示文摘 | Rajkumar T Vijayalakshmi N Gopal G | 2010 | Cancer Cell Int2010，10，1： | 1 |
| 13 | The seroepidemiology of herpes simpex virus type 1in Europe显示文摘 | Pebody RG Andrews N Brown D Gopal R De Melker H Francois G | 2004 | Sex Transm Infect2004，80，3： | 1 |
| 14 | Oxidation of alkanes by tert-butyl hydroperoxide catalyzed by polynuclear manganese Schiff base complexs显示文摘 | Gopal L T Pralhad A G Sheo S | 1997 | J Mol Catal A: Chem1997，121，： | 1 |
| 15 | Gender-related differences in spatial abilities显示文摘 | Self G M Gopal S Golledge R G | 1992 | Progress in Human Geography1992，16，： | 1 |
| 16 | Oxyfunctionalization of cyclohexane catalyzed by oxo-bfidged manganese schiff base complexes 显示文摘 | Pralhad A G Gopal L T Sheo Satish | 1995 | Tetrahedron Lett1995，35，48： | 1 |
| 17 | Identification and validation of genes involved in gastric tumorigenesis显示文摘 | Rajkumar T Vijayalakshmi N Gopal G | 2010 | Cancer Cell Int2010，10，1： | 1 |
| 18 | A neural network method for mixture estimation for vegetation mapping 显示文摘 | Carpenter G A Gopal S Macomber S | 1999 | Remote sensing of Environment1999，70，2： | 1 |
| 19 | Conserved nuclear export sequences in Schizosaccharomyces pombe Mex67 and human TAP function in mRNA export by direct nuclear pore interactions显示文摘 | Thakurta AG Gopal G Yoon JH | 2004 | J Biol Chem2004，279，17： | 1 |
| 20 | Whole genome sequencing and analysis of plant growth promoting bacteria isolated from the rhizosphere of plantation crops coconut, cocoa and arecanut 显示文摘 | Gupta A Gopal M Thomas G V | 2014 | PLoS One2014，9，10： | 1 |
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