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| 1 | 运用彗星试验检测麝香酮对苯并(a)芘致DNA损伤的影响显示文摘[目的]研究麝香酮在体内试验条件下 ,对苯并(a)芘致小鼠肝和肺细胞核DNA损伤的影响。[方法]SENCAR雄性成年小鼠灌胃 ,分别单独给予苯并(a)芘125、250、500mg/(kg·bw·d)和用麝香酮250、500mg/(kg·bw·d)预处理后再给予苯并(a)芘125mg/(kg·bw·d) ,处死动物后分离小鼠肝和肺组织细胞核做彗星测试 ,采用CCD成像分析系统分析彗星 ,取尾相 (olivertailmoment,OTM)值判断DNA损伤强度。[结果]苯并(a)芘各浓度组均出现小鼠肝和肺细胞OTM值的明显增加 ,高浓度麝香酮[500mg/(kg·bw·d)]可引起小鼠肝细胞OTM值的轻度增加。用高浓度麝香酮预处理小鼠后再给予苯并(a)芘 ,所观察到的肝、肺的DNA损伤 (肝OTM值为7.6、肺为11)较之苯并(a)芘单独染毒引起的DNA损伤(肝OTM值为5.1、肺为6.9)增加更明显。[结论]麝香酮能明显增强苯并(a) | 鲁文清 Richard Gminski Volker Mersch-Sundermann | 2004 | 环境与职业医学2004，21，1： | 3 |
| 2 | Endothelium dysfunction markers in patients with diabetic retinopathy显示文摘 | Siemianowicz K Francuz T Gminski J | 2005 | Int J Mol Med2005，15，3： | 1 |
| 3 | Blood antioxidant parameters in patients with diabetic retinopathy显示文摘 | Siemianowiez K Gminski J Telega A | 2004 | Int J Mol Med2004，14，： | 1 |
| 4 | Sensory irritations and pulmonary effects in human volunteers following short-term exposure to pinewood emissions显示文摘 | Gminski R Marntzky R Kevekordes S | 2011 | Journal of Wood Science2011，57，5： | 1 |
| 5 | Hierarchical predictive control of intergrated wastewater treatment systems 显示文摘 | Brdys M A Grochowski M Gminski T | 2008 | Control Engineering Practice2008，16，6： | 1 |
| 6 | Soluble ICAM-1,VCAM-1 and Eselectin m children from families with high risk of athcrosclcrosis显示文摘 | Wojakowski W Gminski J | 2001 | Int J Mol Med2001，7，2： | 1 |
| 7 | Soluble ICAM-1,VCAM-1 and E-selectin in children from families with high risk of atherosclerosis显示文摘 | Wojakowski W Gminski J | 2001 | Int J Mol Med2001，7，2： | 1 |
| 8 | Methylenetetrahydrofolate reductase gene C677T and A1298C polymorphisms in patients with small cell and nonsmall cell lung cancer 显示文摘 | Siemianowicz K Gminski J Garczorz W | 2003 | Oncol Rep2003，10，5： | 1 |
| 9 | Endothelium dysfunction markers in patients with diabetic retinopathy显示文摘 | Krzysztof Siemianowicz Tomasz Francuz Jan Gminski Alicja Telega Marcin Syzdól | 2005 | International Journal of Molecular Medicine2005，，3： | 1 |
| 10 | Methylenetetrahydrofolate reductase gene C677T and A1298C polymorphisms in patients with small cell and nonsmall cell lung cancer显示文摘 | Siemianowicz K Gminski J Garczorz W | 2003 | Oncol Rep2003，10，5： | 1 |
| 11 | Hierarchical predictive control of integrated wastewater treatment systems显示文摘 | Bryds M A Grochowski M Gminski T | 2008 | Control Eng Pract2008，16，6： | 1 |
| 12 | Genotoxic effects of three selected black toner powders and their dimethyl sulfoxide extracts in cultured human epithelial A549 lung cells in vitro 显示文摘 | Gminski R Decker K Heinz C | 2011 | Environmental and Molecular Mutagenesis2011，52，4： | 1 |
| 13 | Oxidative stress and inflammatory response to printer toner particles in human epithelial A549 htng cells 显示文摘 | Konczol M Weiss A Gminski R | 2013 | Toxicology Let- ters2013，216，23： | 1 |
| 14 | Investigations on cytotoxic and genotoxic effects of laser printer emis- sions in human epithelial A549 lung cells using an air/ liquid exposure system 显示文摘 | Tang T Gminski R Konczol M | 2012 | Environmental and Molec- ular Mutagenesis2012，53，2： | 1 |
| 15 | Endotbehum elystunctionmarkers in patients with diabetic retinopathy显示文摘 | Siemianowicz K Franeuz T Gminski J | 2005 | Int J Mol Med2005，15，： | 1 |
| 16 | Methylenetetrahydrofolate reductase gene C677T and A1298C polymorphisms in patients with small cell and non-small cell lung cancer显示文摘 | Siemianowicz K Gminski J Garczorz W | 2003 | Oncol Rep2003，10，5： | 1 |
| 17 | Serum total cho- lesterol and triglycerides levels in patients with lung cancer显示文摘 | Siemianowicz K Gminski J Stajszczyk M | 2000 | Int J Mol Med2000，5，2： | 1 |
| 18 | Soluble ICAM-1,VCAM-1 and E-selectin in chil-dren from families with high risk of atherosclerosis显示文摘 | Wojakowski W Gminski J | 2001 | Int J Mol Med2001，7，2： | 1 |
| 19 | Serum HDL cholesterol concen- tration in patients with squamous cell and small cell lung cancer显示文摘 | Siemianowiez K Gminski J | 2000 | International Journal of Molecular Medicine2000，6，3： | 1 |
| 20 | Hierarchical predictive control of integrated wastewater treatment systems 显示文摘 | Brdys M A Grochowski M Gminski T Konarczak K Drewa M | 2008 | Control Engineering Practice2008，16，6： | 1 |
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