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| 1 | Molecular classifications of gastric cancers: Novel insights and possible future applications显示文摘Despite some notable advances in the systemic management of gastric cancer(GC), the prognosis of patients with advanced disease remains overall poor and their chance of cure is anecdotic. In a molecularly selected population, a median overall survival of 13.8 mo has been reached with the use of human epidermal growth factor 2(HER2) inhibitors in combination with chemotherapy, which has soon after become the standard of care for patients with HER2-overexpressing GC. Moreover, oncologists have recognized the clinical utility of conceiving cancers as a collection of different molecularlydriven entities rather than a single disease. Several molecular drivers have been identified as having crucial roles in other tumors and new molecular classifications have been recently proposed for gastric cancer as well. Not only these classifications allow the identification of different tumor subtypes with unique features, but also they serve as springboard for the development of different therapeutic strategies. Hopefully, the application of standard systemic chemotherapy, specifictargeted agents, immunotherapy or even surgery in specific cancer subgroups will help maximizing treatment outcomes and will avoid treating patients with minimal chance to respond, therefore diluting the average benefit. In this review, we aim at elucidating the aspects of GC molecular subtypes, and the possible future applications of such molecular analyses. | Silvio Ken Garattini Debora Basile Monica Cattaneo Valentina Fanotto Elena Ongaro Marta Bonotto Francesca V Negri Rosa Berenato Paola Ermacora Giovanni Gerardo Cardellino Mariella Giovannoni Nicoletta Pella Mario Scartozzi Lorenzo Antonuzzo Nicola Silvestris Gianpiero Fasola Giuseppe Aprile | 2017 | World Journal of Gastrointestinal Oncology2017，9，5： | 5 |
| 2 | Patterns of recurrence and outcome according to breast cancer subtypes in lymph node-negative disease:results from international breast cancer study group trials VIII and IX显示文摘 | Otto MF Zhouxin S Giuseppe V | 2013 | J Clin Oncol2013，31，25： | 1 |
| 3 | Comparison of the usefulness of cardiac resynchronization therapy in three age-groups (<65, 65-74 and ≥75 Years) (from the InSync/InSync ICD Italian Registry)显示文摘 | Stefano F Sergio V Giuseppe B | 2011 | Am J Cardiol2011，107，10： | 1 |
| 4 | Hyperbaric oxygen therapy with short duration intratympanic steroid ther- apy for sudden hearing loss 显示文摘 | Roberto F Giuseppe A Marika V | 2012 | Acta Oto - laryngologi- ca2012，，5： | 1 |
| 5 | Adeno-associated virus (AAV) vectors achieve prolonged transgene expression in mouse myocardium and arteries in vivo: a comparative study with adenovirus vectors显示文摘 | GIUSEPPE V HANSRUEDI B JEAN D | 2003 | Int J Cardiol2003，90，223： | 1 |
| 6 | Innovative supercritical CO2 extraction of lycopene from tomato in the presence of vegetable oil as cosolvent显示文摘 | GIUSEPPE V A LUIGIA L LEONARDO R B | 2004 | Journal of supercritical Fluids2004，29，： | 1 |
| 7 | Optimisation of storage allocation in order picking operations through a genetic algorithm显示文摘 | Eleonora B Margherita C Giuseppe V | 2012 | International Journal of Logistics:Research and Applications2012，15，2： | 1 |
| 8 | Prognostic value of the metabolic syndrome in essential hypertension显示文摘 | Giuseppe S Matteo P Gaetano V | 2004 | J Am Coll Cardiol2004，43，10： | 1 |
| 9 | Correlation of visual function impairment and optical coherence tomography findings in patients with adultonset foveomacular vitelliform macular dystrophy显示文摘 | Giuseppe Q Anna V Prato BR | | 0，，： | 1 |
| 10 | Noradrenergic vascular hyper-responsiveness in human hypertension is dependent on oxyfen free radical impairment of nitric oxide activity显示文摘 | Carmine V Raffaele I | 2000 | Circulation2000，102，5： | 1 |
| 11 | Role of Leptin in the Activation of Immune Cells显示文摘 | Patricia Fernández-Riejos Souad Najib Jose Santos-Alvarez Consuelo Martín-Romero Antonio Pérez-Pérez Carmen González-Yanes Víctor Sánchez-Margalet Giuseppe Matarese | 2010 | Mediators of Inflammation2010，，： | 1 |
| 12 | Extrapersonal visual unilateral spatial neglect and its neuroanatomy显示文摘 | Giuseppe V | | 0，，1： | 1 |
| 13 | Plasticizers infant nutrition and reproductive health 显示文摘 | Giuseppe L Claudio D F Alberto V | 2004 | Reproductive Toxicology2004，19，1： | 1 |
| 14 | C2H6 as an active carbon source for a large scale synthesis of carbon nanotubes by chemical vapor deposition显示文摘 | Giuseppe G Ricardo V Julien A | 2005 | Appl Catal2005，279，： | 1 |
| 15 | Correlation of visual function impairment and optical coherence tomography findings in patients with adult-onset foveomacular vitellifonn macular dystrophy 显示文摘 | Giuseppe Q Anna V Prato BR Cristianna I Eric H | 2008 | Am J Ophthalmol2008，146，10： | 1 |
| 16 | Disturbance torque estimation in a sensorless dc drive显示文摘 | GIUSEPPE S BUJA R M MARIA I V | | 0，，04： | 1 |
| 17 | Innovative supercritical CO2 extraction of lycopene from tomato in the presence of vegetable oil as co-solvent显示文摘 | GIUSEPPE V LUIGIA L LEONARDO R | 2004 | J Supercrit Fluids2004，29，： | 1 |
| 18 | Thermal characterization of compact electronic systems: a portable PC as a study case 显示文摘 | ENRICO D GIUSEPPE V | 2002 | IEEE Transactions on Power Electronics2002，17，2： | 1 |
| 19 | Sliding mode neuro-adaptive control of electronic drives 显示文摘 | ANDON V T GIUSEPPE L C VINCENZO G | 2007 | IEEE Transactions on Industrial Electronics2007，54，1： | 1 |
| 20 | Prognostic value of the metabolic syn- drome in essential hypertension显示文摘 | Giuseppe S Matteo P Gaetano V | 2004 | J Am Coil Cardio12004，43，： | 1 |
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