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| 1 | Dementia studies in Chinese populations显示文摘Variations in the prevalence of dementia in different ethnic groups have been reported worldwide, and a number of reviews have provided a picture of epidemiological studies in dementia research. However, little is known about epidemiological studies in Chinese populations. In this review, we searched PubMed and the Web of Science for original research articles published in English up to July 2013 on the prevalence, incidence, risk factors, and prognosis of dementia in Chinese populations worldwide. Except for the prevalence, we included only population-based follow-up studies. We identified 25 studies in elderly Chinese residents in China's Mainland, Hong Kong, Taiwan, and Singapore, and found a higher prevalence of dementia in China's Mainland than in the other locations, which may be due to that the studies from China's Mainland are more recent than those from other locations. A notable increase in incidence was observed when dementia cases were diagnosed using 10/66 diagnostic criteria compared to other criteria. Studies on risk factors for dementia were limited and mostly from China's Mainland. Age, gender, education, smoking, and alcohol consumption were related to the risk of dementia in Chinese populations. Only two prognostic studies were identifi ed, and age, gender, and residential area were related to the prognosis of dementia. In conclusion, the prevalence, incidence, and risk factors for dementia found in Chinese populations were comparable to other ethnic groups, but no conclusive results on prognosis were found. The differences in prevalence and incidence were influenced by the diagnostic criteria and the time of study. Longitudinal population-based studies on the incidence, risk factors, and prognosis of dementia in Chinese populations are required. | Jin-Jing Pei Maria Stella T. Giron Jianping Jia Hui-Xin Wang | 2014 | Neuroscience Bulletin2014，30，2： | 13 |
| 2 | 5-ASA colonic mucosal concentrations resulting from different pharmaceutical formulations in ulcerative colitis显示文摘AIM:To compare the mucosal concentrations of 5-aminosalicylic acid(5-ASA)resulting from different pharmaceutical formulations and analyse the influence of inflammation on the mucosal concentrations.METHODS:The study included 130 inflammatory bowel disease(IBD)patients receiving 5-ASA as pH-dependent-release formulations(73 patients),time-dependent-release formulations(11 patients),or pro-drugs(18patients).In addition,28 patients were receiving topical treatment(2-4 g/d)with pH-dependent-release formulations.Endoscopic biopsies were obtained from the sigmoid region during the colonoscopy.The 5-ASA concentrations(ng/mg)were measured in tissue homogenatesusing high-pressure liquid chromatography with electrochemical detection.The t test and Mann-Whitney test,when appropriate,were used for statistical analysis.RESULTS:Patients receiving pH-dependent-release formulations showed significantly higher mucosal concentrations of 5-ASA(51.75±5.72 ng/mg)compared with patients receiving pro-drugs(33.35±5.78 ng/mg,P=0.01)or time-dependent-release formulations(38.24±5.53 ng/mg,P=0.04).Patients with endoscopic remission had significantly higher mucosal concentrations of5-ASA than patients with active disease(60.14±7.95ng/mg vs 35.66±5.68 ng/mg,P=0.02).Similar results were obtained when we compared patients with the histological appearance of remission and patients with active histological inflammation(67.53±9.22 ng/mg vs 35.53±5.63 ng/mg,P<0.001).Significantly higher mucosal concentrations of 5-ASA were detected in patients treated with both oral and topical treatments in combination compared with patients who received oral treatment with pH-dependent-release formulations alone(72.33±11.23 ng/mg vs 51.75±5.72 ng/mg,P=0.03).CONCLUSION:IBD patients showed significant variability in mucosal 5-ASA concentrations depending on the type of formulation,and the highest mean concentration was achieved using pH-dependent-release formulations. | Renata D’Incà Martina Paccagnella Romilda Cardin Surajit Pathak Vincenzo Baldo Maria Cecilia Giron Giacomo Carlo Sturniolo | 2013 | World Journal of Gastroenterology2013，19，34： | 4 |
| 3 | 低剂量左旋布比卡因3mg复合芬太尼10μg脊髓麻醉在妇科门诊腹腔镜手术中的应用显示文摘背景对于妇科门诊腹腔镜这种短时手术来说,选择利多卡因进行脊髓麻醉是十分有效的。本研究中,我们对比了利多卡因.芬太尼与左旋布比卡因-芬太尼脊髓麻醉在短时妇科腹腔镜手术中的麻醉效果、麻醉恢复时间和患者满意度。方法在这项双盲研究中,52例拟行输卵管绝育术的健康妇女被随机分为组Ⅰ(椎管内注射2%利多卡因10mg加芬太尼10μg)和组Ⅱ(椎管内注射0.5%左旋布比卡因3mg加芬太尼10μg),每组药物用灭菌水稀释至3ml。术中需要监测以下指标:麻醉起效时间、是否需要补充麻醉一镇痛药物、镇静深度、手术条件以及血流动力学方面的事件。术后,通过测试运动阻滞情况、本体感觉、振动觉、轻触觉和进行Romberg试验来评估患者是否可以不去麻醉恢复室并独立行走。麻醉给药后5、10、15分钟测试感觉阻滞平面,之后每15分钟测试一次直至感觉完全恢复。感觉阻滞恢复时间的差异达25分钟被认为在临床上是有意义的。结果两组的麻醉起效时间和术中条件相同。没有患者需要全身麻醉来完成手术。所有两组患者都不需要去麻醉恢复室。组Ⅰ患者在27分钟(18-45分钟)后可行走,组Ⅱ30分钟(18。56分钟)后可行走(P=0.24)。脊髓麻醉完全恢复组Ⅰ需要93分钟(65-120分钟),组Ⅱ需要105分钟(78-150分钟)(P=0.019);然而,出院时间两组没有区别,组Ⅰ为185分钟(150-300分钟),组Ⅱ为188分钟(125-300分钟)(P=0.62)。两组患者的总体满意度也相似。结论左旋布比卡因3mg复合芬太尼10μg可以替代利多卡因10mg复合芬太尼10μg用于短时手术的脊髓麻醉。前者在临床中可以达到与后者相当的感觉阻滞恢复时间、术中条件和患者满意度。 | Jesus de Santiago, DESA, MD Javier Santos,Yglesias, MD Jorge Giron, MD Frandsco Montes de Oca, MD Alejandro Jimenez, PhDl Pilar Diaz, PhD | 2012 | 麻醉与镇痛2012，8，1： | 3 |
| 4 | 针灸可改善乳腺癌患者术后患肢功能障碍显示文摘巴西圣保罗联邦大学的Giron教授等人公布了一项最新研究结果,针灸治疗对乳腺癌患者术后肢体功能障碍的恢复效果显著,具有安全、微创、耐受性好的特点,可减轻乳腺癌患者术后的身心问题,提高其生活质量。该研究共纳入50例18岁以上、术后3个月仍有肩胛带、上肢及颈胸椎疼痛,且视觉模拟评分法(VAS)≥3分的女性乳腺癌患者,排除双侧乳腺切除、转移性肿瘤、静脉炎和肢体触觉感觉障碍、 | 刘少华 王琦 Giron PS Haddad CA Lopes de Almeida Rizzi SK | 2017 | 护士进修杂志2017，32，14： | 3 |
| 5 | Diagnostic approach to mediastinal masses显示文摘 | Giron J Fojadet P Saus N | 1998 | EurJ Radiol1998，27，： | 1 |
| 6 | Purification and characterisation of a haemorrhagic fraction from the venom of the Uracoan rattlesnake Crotalus vegrandis显示文摘 | Aguilar 1 Giron M E Rodriguez-Acosta A | 2001 | Biochim Biophys Acta2001，1548，1： | 1 |
| 7 | Blocked diisocyanates as reactive coupling agents: application to pine fiber-polypropylene composites显示文摘 | GIRONES J PIMENTA M T B VILASECA F | 2008 | Carbohydrate polymers2008，74，1： | 1 |
| 8 | Natural fiber-reinforced thermoplastic starch composites obtained by melt processing 显示文摘 | GIRONES J LOPEZB J P MUTJE P | 2012 | Compos Sci Technol2012，72，： | 1 |
| 9 | Efficacy and effectiveness of individual family intervention on social and clinical functioning and family burden in severe schizophrenia:a 2-year randomized controlled study 显示文摘 | Giron M Fernadez-Yanez A Mana-Alvarenga S | 2010 | Psychological Medi- cine2010，40，： | 1 |
| 10 | Femoral attachment of the anterior cruciate ligament显示文摘 | Giron F Cuomo P Aglietti P | | 0，，： | 1 |
| 11 | Blocked isocyanates as coupling agents for cellulose-based composites 显示文摘 | GIRONES J PIMENTA M T B VILASECA F | 2007 | Carbohydrate polymers2007，68，3： | 1 |
| 12 | Utilisation of chickpea protein isolates for production of peptides with angiotensin I-converting enzyme(ACE)-inhibitory activity显示文摘 | Pedroche J Yust M M Giron C J | 2002 | Journal of the Science of Food and Agriculture2002，82，9： | 1 |
| 13 | Streptococcus mitis endocarditis显示文摘 | Rapeport K B Giron J A Rosner F | 1986 | Arch Intern Med1986，146，： | 1 |
| 14 | Single-and double-incision double-bundle ACLreconstruction显示文摘 | Aglietti P Giron F Cuomo P | | 0，，454： | 1 |
| 15 | Contribution of TRPV1 to the bradykinin-evoked nociceptive behavior and excitation of cutaneous sensory neurons 显示文摘 | Katanosaka K Banik RK Giron R | 2008 | Neurosci Res2008，62，： | 1 |
| 16 | Multi-gene amplification: simltaneous detection of three virLence genes in diarrhoeal stool 显示文摘 | Frankel G Giron JA Valmassoi J | 1989 | Mol Microbiol1989，3，： | 1 |
| 17 | Polymerase chain reaction for detection of adenoviruses in stool samples 显示文摘 | Girones R Juto P | 1990 | J Clin Microbiol1990，28，12： | 1 |
| 18 | Primary lymphoma ofthe breast:a case of marginal zone B-cell lymphoma显示文摘 | Giron GL Hamlin PA Brogi E | 2004 | AmSurg2004，70，8： | 1 |
| 19 | Immediate allergic reactions by polyethylene glycol 4000:two cases显示文摘 | Ant o n Giron e s M Roan Roan J de la Hoz B | 2008 | Allergol lmmunopathol (Madr)2008，36，2： | 1 |
| 20 | Polymorphism in the pharmaceutical industry 显示文摘 | Giron J | 2001 | Journal of Thermal Analysis and Calorimetry2001，64，： | 1 |
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