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| 1 | Selection of patients and staging of peritoneal surface malignancies显示文摘Peritoneal carcinomatosis (PC) is a common evolution of cancer of the gastrointestinal tract, and has been traditionally regarded as a terminal disease with short median survival. During the last 20 years, thanks to its favourable oncologic results, a new loco-regional therapeutic approach, combining cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC), has an important development. Due to its significant, but acceptable, morbidity and mortality, and high cost, this comprehensive management plan requires knowledgeable patient selection. Quantitative prognostic indicators are required to assess a patient’s eligibility. Large multicenter studies have identified several prognostic factors, which can be used for a better selection of patients who would benefit from the combination of cytoreductive surgery with HIPEC. Indications for treatment of PC with cytoreduction and HIPEC are now validated for several diseases: peritoneal mesothelioma, pseudomyxoma peritonei, PC from the appendix, and colorectal cancer. Indications are still under discussion for gastric and ovarian carcinomatosis. Computed tomography is the best radiological for staging the disease. The extent of peritoneal carcinomatosis is, however, difficult to evaluate preoperatively, and precise evaluation is most often performed during surgical exploration. Cytoreductive surgery associated with HIPEC for the treatment of peritoneal carcinomatosis should be performed for young patients with limited and resectable carcino-matosis, in specialized institutions involved in the management of peritoneal surface malignancies. | Eddy Cotte Guillaume Passot Franois-Noёl Gilly Olivier Glehen | 2010 | World Journal of Gastrointestinal Oncology2010，2，1： | 4 |
| 2 | Major Lunar Crustal Terranes: Surface Expressions and Crest - menlle Origins 显示文摘 | Jolliff B L Gillis J J Haskin L A | 2000 | Journal of Geophysical Research2000，105，2： | 1 |
| 3 | A revised algorithm for calculating TiO2 from Clementine UVVIS data: A synthesis of rock, soil and remotely sensed TiO2 concentrations显示文摘 | Gillis J J Jolliff B L Elphic R C | 2003 | Journal of Geophysical Research2003，108，2： | 1 |
| 4 | Prehabilitation versus rehabilitation: a ran- domized control trial in patients undergoing colorectal resection for cancer显示文摘 | Gillis C Li C Lee L eta| | 2014 | Anesthesiology2014，121，5： | 1 |
| 5 | Advanced heat exchange technology for thermoelectric cooling devices显示文摘 | GILLY M D | 1998 | Trans ASME1998，120，3： | 1 |
| 6 | A tissue-specific transcription enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene 显示文摘 | GILLIES S D MORRISON S L OI V T | 1983 | Cell1983，33，： | 1 |
| 7 | On Stability of Cellular Neural Networks with Delay显示文摘 | Civalleri P P Gilli M Pandolfi L | 1993 | IEEE Tran Circuits Systems1993，40，3： | 1 |
| 8 | Optimal timing for in- travenous administration set replace ment(Review)显示文摘 | Gillies D O' Riordan L Wallen MM et a l | 2005 | Coehrane Database Syst Rev2005，，00： | 1 |
| 9 | Hy- poxia: importance in tumor biology, noninvasive meas- urement by imaging, and value of its measurement in the management of cancer therapy 显示文摘 | TATUM J L KELLOFF G J GILLIES R J | 2006 | Int J Radiat Bi- ol2006，82，10： | 1 |
| 10 | Phar- macological and lifestyle interventions to prevent or delay type 2 diabetes in people with impaired glucose tolerance:systematic review and meta-analysis显示文摘 | Clare L Gillies Keith R Abrams Paul C Lambert | 2007 | BMJ2007，334，： | 1 |
| 11 | 成人2型糖尿病不同筛查及预防策略成本效益分析显示文摘目的 比较针对2型糖尿病预防及治疗的4种筛查策略及随后予以的干预措施:(a)筛查2型糖尿病患者使其能接受早期检查及治疗,(b)筛查2型糖尿病和糖耐量受损患者,对糖耐量受损的人群予以生活方式干预以延缓或预防糖尿病的发生,(c)同(b)但予以药物干预措施,(d)不筛查。
设计 成本效益决策分析建立在对概率的发展和评估基础上,是从筛查到死亡的综合性经济决策分析模型。
研究对象 一组假设人群,筛查时年龄45岁,高于平均糖尿病风险水平。
数据来源 电子书目数据库收录的已发表的临床试验和流行病学研究;补充数据分别来自英国和威尔士健康统计署、风险筛查(STAR)研究和ADDITION研究的Leicester部分。
方法 建立一种决策树/Markov混合模型,以模拟每一种筛查策略的长期效用,包括临床和成本效益终点。该模型假设水平跨度为50年时间,其成本效益折损率为3.5%。采用敏感度分析以验证模型假设及确定哪种模型数据输入对结果的影响最大。
结果 与不筛查策略比较,筛查2型糖尿病、筛查糖尿病和糖耐量受损并予以生活方式干预、筛查糖尿病和糖耐量受损并予以药物干预治疗3种策略,每获得一个质量调整生命年(QALY)估计所需成本分别为(每年成本效益贴现率为3.5%)14150英镑(17560欧元;27860美元)、6242英镑和7023英镑。在支付意愿阈值为20000英镑时,各主动筛查策略通过干预产生的成本效益概率分别为49%,93%和85%。
结论 对年龄45岁、高于平均风险水平的人群进行2型糖尿病和糖耐量受损的筛查,并对糖耐量受损人群予以适当的干预似乎具有很好的成本效益。单独筛查糖尿病而不对糖耐量受损人群予以干预的策略具有的成本效益仍不确定,需要进一步研究确定早期检测糖尿病的作用。 | Clare L Gillies Paul C Lambert Keith R Abrams Alex J Sutton Nicola J Cooper Ron T Hsu Melanie J Davies Kamlesh Khunti 张晓梅(译) 纪立农(校) | 2008 | 英国医学杂志中文版2008，11，5： | 1 |
| 12 | Hypoxia: importance in tumor biology, noninvasive measurement by imaging, and value of its measurement in the management of cancer therapy 显示文摘 | Tatum J L Kelloff G J Gillies R J | 2006 | Int J Radiat Biol2006，82，10： | 1 |
| 13 | Bioavailability of sediment-associated Cu and Zn to Daphnia magna显示文摘 | GILLIS P L WOOD C M RANVILLE J F | 2006 | Aquatic Toxicology2006，77，4： | 1 |
| 14 | Resistance to photo damage in evergreen conifers显示文摘 | Gillies S L Vidaver W | 1990 | Physiology Plant1990，80，： | 1 |
| 15 | Direct Comparison of Repeated Same-Day Self and Ambulatory Blood Pressure Monitoring显示文摘 | Carney S Gillies A Garvey L | 2005 | Nephrology (Carlton)2005，10，2： | 1 |
| 16 | Reciprocity:Theory and facts显示文摘 | Bruni L Gilli M Pelligra V | | 0，，1： | 1 |
| 17 | Resistance to photo damage in evergreen conifers显示文摘 | GILLIES S L VIDAVER W | 1990 | Physiology Plant1990，80，： | 1 |
| 18 | On stability of cellular neural networks with delay显示文摘 | Civalleri P P Gilli M Pandolfi L | 1993 | IEEE Trans Circ Syst I1993，40，3： | 1 |
| 19 | Reducing pre- mature infants' length of stay and improving parents' mental health outcomes with the Creating Opportunities for Parent Empowerment (COPE) neonatal intensive care unit program: a randomized, con- trolled trial显示文摘 | Melnyk BM Feinstein NF Alpert - Gillis L | 2006 | Pediatrics2006，118，5： | 1 |
| 20 | Gauze and tape and transparent polyurethane dressings for central venous catheters显示文摘 | Gillies D ORiordan L Carr D | 2003 | Cochrane Database Syst Rev2003，4，： | 1 |
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