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| 1 | DMFSGD: adecentralized matrix factorization algorithm for networkdistance prediction显示文摘 | LIAO Y DU W GEURTS P | 2013 | IEEE Transactions on Networking2013，21，5： | 1 |
| 2 | Vortex statistics in tur- bulent rotating conwxtion 显示文摘 | Kunnen R P J Clercx H J H Geurts B J | 2010 | Physical Review E2010，82，36： | 1 |
| 3 | Proteomic Mass Spectra Classification Using Decision Tree Based Ensemble Methods显示文摘 | Geurts P Fillet M Seny D | 2005 | Bioinformatics2005，21，21： | 1 |
| 4 | Motor learning curve andlong- term effectiveness of modified constraint- induced movementtherapy in children with unilateral cerebral palsy:a randomizedcontrolled trial 显示文摘 | Geerdink Y Aarts P Geurts AC | 2013 | Res Dev Disabil2013，34，3： | 1 |
| 5 | Candidate colorectal cancer predisposing gene variants in Chinese early-onset and familial cases显示文摘AIM: To investigate whether whole-exome sequencing may serve as an efficient method to identify known or novel colorectal cancer(CRC) predisposing genes in early-onset or familial CRC cases.METHODS: We performed whole-exome sequencing in 23 Chinese patients from 21 families with nonpolyposis CRC diagnosed at ≤ 40 years of age, or from multiple affected CRC families with at least 1 firstdegree relative diagnosed with CRC at ≤ 55 years of age.Genomic DNA from blood was enriched for exome sequences using the Sure Select Human All Exon Kit, version 2(Agilent Technologies) and sequencing was performed on an Illumina Hi Seq 2000 platform.Data were processed through an analytical pipeline to search for rare germline variants in known or novel CRC predisposing genes.RESULTS: In total, 32 germline variants in 23 genes were identified and confirmed by Sanger sequencing.In 6 of the 21 families(29%), we identified 7 mutations in 3 known CRC predisposing genes including MLH1(5 patients), MSH2(1 patient), and MUTYH(biallelic, 1 patient), five of which were reported as pathogenic.Inthe remaining 15 families, we identified 20 rare and novel potentially deleterious variants in 19 genes, six of which were truncating mutations.One previously unreported variant identified in a conserved region of EIF2AK4(p.Glu738_Asp739insA rgA rg) was found to represent a local Chinese variant, which was significantly enriched in our early-onset CRC patient cohort compared to a control cohort of 100 healthy Chinese individuals scored negative by colonoscopy(33.3% vs 7%, P < 0.001).CONCLUSION: Whole-exome sequencing of early-onset or familial CRC cases serves as an efficient method to identify known and potential pathogenic variants in established and novel candidate CRC predisposing genes. | Jun-Xiao Zhang Lei Fu Richarda M de Voer Marc-Manuel Hahn Peng Jin Chen-Xi Lv Eugène TP Verwiel Marjolijn JL Ligtenberg Nicoline Hoogerbrugge Roland P Kuiper Jian-Qiu Sheng Ad Geurts van Kessel | 2015 | World Journal of Gastroenterology2015，21，14： | 1 |
| 6 | 'Longituclinal study using a diode phantom for helical tomotherapy IMRT QA显示文摘 | GEURTS M GONZALEZ J SERRANO-OJEDA P | 2009 | Medical Phys- ics2009，36，11： | 1 |
| 7 | Full-scale and wind-tunnel measurements of the wind and wind induced pressures over suburban terrain显示文摘 | Geurts C P W | 1996 | Journal of Wind Engineering and Industrial Aerodynamics1996，64，23： | 1 |
| 8 | The Impact of Web Experi- ence on Virtual Buying Behaviour: An Empirical Study 显示文摘 | Constantinides E Geurts P | 2005 | Journal of Customer Behaviour2005，4，3： | 1 |
| 9 | Longitudinal study using a diode phantom for helical tomotherapy IMRT QA显示文摘 | Geurts M Gonzalez J Serrano-Ojeda P | | 0，，： | 1 |
| 10 | Influ- ence of partner diversity on collaborative public R&D pro- ject outcomes: a study of application and commercialization of nanotechnologies in the Netherlands 显示文摘 | RAESFELD A GEURTS P JANSEN M | 2012 | Technovation2012，32，3： | 1 |
| 11 | Inferring regulatory networks from expression data using tree-based methods显示文摘 | IRRTHUM A WEHENKEL L GEURTS P | 2010 | PloS one2010，5，12： | 1 |
| 12 | Proteomic mass spectra classification using decision tree based ensemble methods显示文摘 | Geurts P Fillet M de Seny D | 2005 | Bioinformatics2005，21，14： | 1 |
| 13 | Social comparisons and absenteeism, a structural modeling approach显示文摘 | Geurts S A E Buunk A P Schaufeli W B | 1994 | Journal of Applied Social Psychology1994，，： | 1 |
| 14 | Synthetic spider silk fibers spun from Pyriform Spidroin 2, a glue silk protein discovered in orb-weaving spider attachment discs 显示文摘 | Geurts P Zhao L Hsia Y | 2010 | Biomacromolecules2010，11，12： | 1 |
| 15 | Social comparisons and absenteeism, a structural modeling approach显示文摘 | Geurts S A E Buunk A P Schaufeli W B | 1994 | Journal of Applied Social Psychology1994，，： | 1 |
| 16 | Continuous wavelet transform of wind and wind-induced pressures on a building in suburban terrain显示文摘 | Geurts C P W Hajj M R Tieleman H W | 1998 | Journal of Wind Engineering and Industrial Aerodynamics1998，7476，： | 1 |
| 17 | Earth-mars halo to halo low thrust manifold transfers 显示文摘 | Pergola P Geurts K Casaregola C | 2009 | Celestial Mechanics and Dynamical Astronomy2009，105，1： | 1 |
| 18 | Exploiting SNP Correlations within Random Forest for Genome-wide Association Studies显示文摘 | BOTTA V LOUPPE G GEURTS P | 2014 | PLoS One2014，9，93： | 1 |
| 19 | Proteomic Mass Spectra Classification Using Decision Tree Based Ensemble Methods显示文摘 | Geurts P Fillet M Seny D | 2005 | Bioinformatics2005，21，21： | 1 |
| 20 | Biomarker discovery for inflammatory bowel disease,using proteomic serum profiling显示文摘 | Meuwis MA Fillet M Geurts P | | 0，，： | 1 |
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