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239篇 您的检索式:作者名="Germane S"
    题名 作者 年代 出处 被引量
1Cytokine production in patients with cirrhosis and TLR4 polymorphisms显示文摘AIM:To analyze the cytokine production by peripheral blood cells from cirrhotic patients with and without TLR4 D299G and/or T399I polymorphisms.METHODS:The study included nine patients with cirrhosis and TLR4 D299G and/or T399I polymorphisms,and 10 wild-type patients matched for age,sex and degree of liver failure.TLR4 polymorphisms were determined by sequence-based genotyping.Cytokine production by peripheral blood cells was assessed spontaneously and also after lipopolysaccharide(LPS)and lipoteichoic acid(LTA)stimulation.RESULTS:Patients with TLR4 polymorphisms had a higher incidence of previous hepatic encephalopathy than wild-type patients(78%vs 20%,P=0.02).Spontaneous production of interleukin(IL)-6 and IL-10 was lower in patients with TLR4 polymorphisms than in wild-type patients[IL-6:888.7(172.0-2119.3)pg/m L vs 5540.4(1159.2-26053.9)pg/m L,P<0.001;IL-10:28.7(6.5-177.1)pg/m L vs 117.8(6.5-318.1)pg/m L,P=0.02].However,the production of tumor necrosis factor-α,IL-6 and IL-10 after LPS and LTA stimulation was similar in the two groups.CONCLUSION:TLR4 polymorphisms were associated with a distinctive pattern of cytokine production in cirrhotic patients,suggesting that they play a role in the development of cirrhosis complications.Juan Camilo Nieto Elisabet Sánchez Eva Román Silvia Vidal Laia Oliva Carlos Guarner-Argente Maria Poca Xavier Torras Cándido Juárez Carlos Guarner German Soriano 2014World Journal of Gastroenterology2014,20,46:5
2Hypericum extract and hyperforin : memory-enhancing properities in rodents显示文摘Klusa V Germane S Noldner M 2001Phar- macopsychiatry2001,34,1:1
3Gas Chromatographic Deteminationon of Deoxynivalenol in Wheat with E1ectron Capture Detection显示文摘 Octave Jfrancis Allen S German 1986AOAC int1986,69,5:1
4Visual retrieval of concrete crack properties for automated post-earthquake structural safety evaluation显示文摘ZHU Z GERMAN S BRILAKIS I 2011Automation in Construc- tion2011,20,7:1
5Development of an annotatedlibrary of neutral human milk oligosaccharides 显示文摘WU S TAO N German J B et ai 2010J ProteomeRes2010,9,41:1
6Operative and nonoperativemanagement of blunt hepatic tramna in adults:a single--center report显示文摘Gonrgiotis S Vougas V German∞S 2007Hepatobiliary Pancreat Surgy2007,14,4:1
7Personalmetabolomics as a next generation nutritional assessment 显示文摘GERMAN J B ROBERTS M A WATLDNS S M 2003J Nutr2003,133,12:1
8Annotation and structuralanalysis of sialylated human milk oligosaccharides 显示文摘WU S Grimm R German J B 2011J ProteomeRes2011,10,2:1
9Regulation of insulin gene expression by glucose and calcium in transfectedprimry islet cultures显示文摘German M S Moss L G Rutter W S 1990J Biol Chem1990,256,22:1
10Reasoning about Systems with Many Processes 显示文摘S German A P Sistla 1992Journal of the ACM (S0004-5411)1992,39,:1
11Linking homogenization and densification in W-Ni-Cu alloys through master sintering curve (MSC) concepts显示文摘SETHI G PARK S J JOHNSON J L GERMAN R M 2009Intemational Journal of Refractory Metals and Hard Materials2009,27,4:1
12Metabolomics: building on a century of biochemistry to guide human heallh 显示文摘German J B Hammock B D Watkins S M 2005Metabolomics2005,1,1:1
13An investigation into the composition of amniotic membrane used for ocular surface reconstruction 显示文摘Cooper W Kinoshita S German M 2005Cornea2005,24,:1
14Construction of Parallel A- nalysis of RNA Ends ( PARE ) libraries for the study of cleaved miRNA targets and the RNA degradome显示文摘German M A Luo S Schroth G 2009Nature Protoeols2009,4,3:1
15Wax--based and PEG-based binder system development for metal and ceramic powders显示文摘Yang M J Atre S V German B M 1996Advances in Powder Metallurgy and Partietdate Materials1996,19,5:1
16Adaptive periodic error correction for heidenhain tape encoders显示文摘Michael W Victor K German S 2008SPIE2008,7012,70:1
17Effects of alcohol septal ablation on coronary micro- vascular function and myocardial energetics in hyper- trophic obstructive cardiomyopathy 显示文摘TIMMER S A KNAAPEN P GERMANS T 2011Am J PhysiolHeart CircPhysiol2011,301,:1
18Control of childhood congenital adrenal hyperplasia and sleep activity and quality with morning or evening glucocorticoid therapy显示文摘German A Suraiya S Tenenbaum-Rakover Y 2008J Clin E ndocrinol Metab2008,93,:1
19SOAR Telescope :4 meter high performance mount performance results显示文摘WARNER C M VICTOR K GERMAN S 2004Proceeding of SPIE2004,5495,:1
20Analysis of Fe-Mo-B sintered alloys显示文摘German R M Hwang K S Madands 1987Powder Metal Int1987,19,2:1
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