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| 1 | Bouveret's syndrome complicated by a distal gallstone ileus显示文摘AIM: Gastric outlet obstruction caused by duodenal impaction of a large gallstone migrated through a cholecystoduodenal fistula has been referred as Bouveret's syndrome. Endoscopic lithotomy is the first-step treatment,however, surgery is indicated in case of failure or complication during this procedure.METHODS: We report herein an 84-year-old woman presenting with features of gastric outlet obstruction due to impacted gallstone. She underwent an endoscopic retrieval which was unsuccessful and was further complicated by distal gallstone ileus. Physical examination was irrelevant.RESULTS: Endoscopy revealed multiple erosions around the cardia, a large stone in the second part of the duodenum causing complete obstruction, and wide ulceration in the duodenal wall where the stone was impacted. Several attempts of endoscopic extraction by using foreign body forceps failed and surgical intervention was mandatory. Preoperative ultrasound evidenced pneumobilia whilst computerized tomography showed a large stone, 5 cm×4 cm×3 cm, loggingat the proximal jejunum and another one, 2.5 cm×2 cm×2 cm,in the duodenal bulb causing a closed-loop syndrome. She underwent laparotomy and the jejunal stone was removed by enterotomy. Another stone reported as located in the duodenum preoperatively was found to be present in the gallbladder by intraoperative ultrasound. Therefore,cholecystoduodenal fistula was broken down, the stone was retrieved and cholecystectomy with duodenal repair was carried out. She was discharged after an uneventful postoperative course.CONCLUSION: As the simplest and the least morbid procedure, endoscopic stone retrieval should be attempted in the treatment of patients with Bouveret's syndrome.When it fails, surgical lithotomy consisting of simple enterotomy may solve the problem. Although cholecystectomy and cholecystoduodenal fistula breakdown is unnecessary in every case, conditions may urge the surgeon to perform such operations even though they carry high morbidity and mortality. | Rasim Gencosmanoglu Resit Inceoglu Caglar Baysal Sertac Akansel Nurdan Tozun | 2003 | World Journal of Gastroenterology2003，9，12： | 9 |
| 2 | Gastric polypoid lesions:Analysis of 150 endoscopic polypectomy specimens from 91 patients显示文摘AIM: To analyze gastric polypoid lesions in our patientpopulation with respect to histopathologic features and demographic, clinical, and endoscopic characteristics of patients.METHODS: Clinical records and histopathologic reports of patients with gastric polypoid lesions were analyzed retrospectively. All lesions had been totally removed by either endoscopic polypectomy or hot biopsy forceps. The histopathologic slides were re-evaluated by the same histopathologist.RESULTS: One-hundred and fifty gastric polypoid lesions were identified in 91 patients. There were 53 (58%) women and 38 (42%) men with a median age of 53 (range, 31 to 82) years. The most frequent presenting symptom was dyspepsia that was observed in 35 (38.5%) patients.Symptoms were mostly related to various associated gastric abnormalities such as chronic gastritis or H pylori infection rather than polypoid lesion itself. Polypoid lesions were commonly located in the antrum followed by cardia. Out of 150 lesions, 80 (53%) had the largest dimensions less than or equal to 5 mm and only 7 were pedunculated. The frequencies of hyperplastic polyps, foveolar hyperplasia, and fundic gland polyps were 46%, 18%, and 14% respectively.We also detected gastritis varioliformis in 12 specimens,lymphoid follicles in 9, 4 adenomatous polyps in 4, polypoid lesions with edematous mucosa in 4, inflammatory polyps in 3, and carcinoid tumor in 1. Adenomatous changes were observed within two hyperplastic polyps and low grade dysplasia in one adenoma. Histopathologic evaluation of the surrounding gastric mucosa demonstrated chronic gastritis in 72 (79%) patients and H pylori infection in 45 (49%).CONCLUSION: Hyperplastic polyps are the most frequently encountered subtype of gastric polypoid lesions. They are usually associated with chronic gastritis or H pylori gastritis. Contrary to the previous belief, they may harbour adenomatous changes or dysplastic foci.Therefore, endoscopic polypectomy seems as a safe and fast procedure for both diagnosis and treatment of gastric polypoid lesions at the same session. In addition,edematous mucosa may appear misleadingly as a polypoid lesion in some instances and it can be ruled out only by histopathologic examination. | Rasim Gencosmanoglu Ebru Sen-Oran Ozlem Kurtkaya-Yapicier Erol Avsar Aydin Sav Nurdan Tozun | 2003 | World Journal of Gastroenterology2003，9，10： | 8 |
| 3 | Late results of split-grafted penoscrotal avulsion injuries显示文摘 | Gencosmanoglu R Bilkay U Alper M | 1995 | J Trauma1995，39，6： | 1 |
| 4 | Isolated metachronous splenic metastasis from synchronous colon cancer显示文摘 | Gencosmanoglu R Aker F Kir G | 2006 | World J Surg Oncol2006，6，4： | 1 |
| 5 | Modified lay-open(incision,curettage,partial lateral wall excision and marsupialization) versus total excision with primary closure in the treatment of chronic sacrococcygeal pi-lonidal sinus显示文摘 | Gencosmanoglu R Inceoglu R | | 0，，： | 1 |
| 6 | Effects of some nonsteroidal anti-inflammatory drugs on articular cartilage of rats in an experimental model of osteoarthritis显示文摘 | GENCOSMANOGLU BE ERYAVUZ M DERVISOGLU S | 2001 | Res Exp MED (Berl)2001，200，3： | 1 |
| 7 | A great misfortune : second traumatic spinal cord injury 显示文摘 | Kafada A Gencosmanoglu BE Hanci M | 2002 | Spinal Cord2002，1，： | 1 |
| 8 | Late Results ofsplit-grafted penoscrotal avulsion injuries显示文摘 | GENCOSMANOGLU R BILKAY U ALPER M | 1995 | J Trauma1995，39，3： | 1 |
| 9 | Modified lay-open (incision,curettage,partial lateral wall excision and marsupialization)versus total excision with primary closure in the treatment ofchronic sacrococcygeal pilonidal sinus: a prospective,randomized clinical trial with a complete two-year follow-up显示文摘 | Gencosmanoglu R Inceoglu K | 2005 | Int J Colorectal Dis2005，20，： | 1 |
| 10 | A great misfortune:second traumatic spinal cord injury显示文摘 | Kafada A Gencosmanoglu BE Hanci M | | 0，，： | 1 |
| 11 | Hemorrhoidectomy :open or closed technique? A prospective, randomized clinicaltrial显示文摘 | Gencosmanoglu R Sad 0 Koc D | 2002 | Dis Colon Rectum2002，45，： | 1 |
| 12 | Hemor- rhoidectomy: open or closed technique显示文摘 | Gencosmanoglu R Orhan S Demet K | 2002 | Dis Colon Rectum2002，45，1： | 1 |
| 13 | Percutaneous endoscopic gastrostomy:a safe and ef-fective bridge for enteral nutrition in neurological or non-neurological conditions显示文摘 | Gencosmanoglu R | 2004 | Neurocrit Care2004，1，3： | 1 |
| 14 | The inhibitory effect of octreotide on experimental colorectal carcinogenesis显示文摘 | Gencosmanoglu R Bugra D Bulut T | 2002 | Surg Today2002，32，3： | 1 |
| 15 | Quality of life of primary caregivers of spinal cord iniury survivors living in the community: Controlled study with short form-36 questionnaire显示文摘 | Unalan H Gencosmanoglu B Akgun K | 2001 | Spinal Cord2001，39，6： | 1 |
| 16 | A Great Misfortune: Second Traumatic Spinal Cord Injury 显示文摘 | Kafadar A Gencosmanoglu BE Hanci M | 2002 | Spinal Cord2002，40，1： | 1 |
| 17 | Effects of an angiotensin Ⅱ receptor antagonist on urinary albumin excretion, left ventricular mass, and systolic and diastolic blood pressures in essential hypertension显示文摘 | Karakoc A Arinsoy T Gencosmanoglu O | 1999 | Clinical foucus1999，60，2： | 1 |
| 18 | A great misfortune:secondtraumatic spinal cord injury显示文摘 | Kafadar A Gencosmanoglu BE Hanci M | 2002 | Spinal cord2002，40，1： | 1 |
| 19 | The inhibitory effect of octreotide on experimental colorectal carcinogenesis显示文摘 | Gencosmanoglu R Bugra D Bulut T | 2002 | Surg Today2002，32，3： | 1 |
| 20 | Modified lay-open( incision, curettage, partial lateral wall excision and marsupialization)versus total excision with primary closure in the treatment of chronic sacrococcygeal pilo nidal sinus显示文摘 | Gencosmanoglu R Inceoglu R | 2005 | Int J Colorectal Dis2005，20，： | 1 |
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