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| 1 | Genetic variations of bile salt transporters as predisposing factors for drug-induced cholestasis, intrahepatic cholestasis of pregnancy and therapeutic response of viral hepatitis 显示文摘 | Stieger B Geier A | 2011 | Expert Opin Drug Metab Toxicol2011，7，4： | 1 |
| 2 | PTA versus Palmaz stent placement in femoropopliteal artery stenoses : Results of a multicenter prospective randomized study ( REFSA )显示文摘 | Grenacher L Saem T Geier A | 2004 | Rofo2004，176，9： | 1 |
| 3 | AN2 of oral bioavail- ability: transporters as gatekeepers in the gut 显示文摘 | Dietrich CG Geier A Oude Elferink RP | 2003 | Gut2003，52，12： | 1 |
| 4 | Genetic variations of bile salt transporters as predisposing factors for drug-induced cholestasis,intrahepatic cholestasis of pregnancy and therapeutic response of viral hepatitis显示文摘 | Stieger B Geier A | | 0，，04： | 1 |
| 5 | Principles of hepatic organic anion transporter regulation during cholcstasis, inflammation and liver regeneration 显示文摘 | Geier A Wagner M Dietrich CG | 2007 | Biochim Biophys Acta2007，1773，3： | 1 |
| 6 | Multidrug resis-tance and response to antiretroviral treatment显示文摘 | DIETRICH C G GEIER A MATERN S | 2002 | Lancet2002，359，9323： | 1 |
| 7 | Air-stable All-inorganicNanocrystal Solar Cells Processed from Solution显示文摘 | Gur I Fromer N A Geier M L | 2005 | Science2005，310，5747： | 1 |
| 8 | Cytokine blockade inhibits hepatic tissue inhibitor of metalloproteinase - 1 expression and up - regulates matrix metalloproteinase - 9 in toxic liver injury 显示文摘 | Roderfeld M Geier A Dietrich CG | 2006 | Liver Int2006，26，5： | 1 |
| 9 | Quantitative anal-ysis of diffusion-weighted magnetic resonance imaging in ma-lignant breast lesions using different b value combinations显示文摘 | Nilsen LB Fangberget A Geier 0 | 2013 | Eur Radiol2013，23，4： | 1 |
| 10 | Regulation of basolateral organic anion transporters in ethinylestradiol-induced cholestasis in the rat显示文摘 | Geier A Dietrich C G Gerloff T | 2003 | Biochim Biophys Acta2003，1609，1： | 1 |
| 11 | On the use of single-film models to describe the oxy-fuel combustion of pulverized coal char 显示文摘 | GEIER M SHADDIX C R DAVIS K A | 2012 | Applied Ener- gy2012，93，67： | 1 |
| 12 | 显示文摘 | Gur I Fromer N A Geier M L | 2005 | Science2005，310，： | 1 |
| 13 | Regulation of basolateral organic anion transporters in ethinylestradiol-induced cholestasis in the rat显示文摘 | Geier A Dietrich C G Gerloff T | 2003 | Biochim Biophys Acta2003，1609，1： | 1 |
| 14 | Structure-based ligand discovery for the large-neutral amino acid transporter 1,LAT-1显示文摘 | GEIER E G SCHLESSINGER A FAN H | 2013 | PNAS2013，110，14： | 1 |
| 15 | ABC of oral bioavail-ability:transporters as gatekeepers in the gut显示文摘 | Dietrich CG Geier A Oude Elferink RP | 2003 | Gut2003，52，12： | 1 |
| 16 | Air-stable all-inorganic nanocrystal solar cells processed from solution显示文摘 | GUR I FROMER N A GEIER M L | | 0，，5747： | 1 |
| 17 | Mechanisms of disease : mecha- nisms and clinical implications of cholestasis in sepsis 显示文摘 | Geier A Fickert P Tranner M | 2006 | Nat Clin Pract Gastroenterol Hepatol2006，3，10： | 1 |
| 18 | Reflux patterns in the ovarian and hypogastric veins in patients with varicose veins and signs of pelvic venous incompetence 显示文摘 | Geier B Barbcra L Mumme A | 2007 | Chir Ital2007，59，4： | 1 |
| 19 | Quantitative analysis of diffusion-weighted magnetic resonance imaging in malignant breast lesions using different b value combinations显示文摘 | Nilsen LB Fangberget A Geier O | | 0，，4： | 1 |
| 20 | A two-phase study evaluating the relationship between Thimerosal-containing vaccine administration and the risk for an autism spectrum disorder diagnosis in the United States显示文摘Background:Autism spectrum disorder(ASD)is defined by standardized criteria of qualitative impairments in social interaction,qualitative impairments in communication,and restricted and stereotyped patterns of behavior,interests,and activities.A significant number of children diagnosed with ASD suffer a loss of previously-acquired skills,which is suggestive of neurodegeneration or a type of progressive encephalopathy with an etiological pathogenic basis occurring after birth.To date,the etiology of ASD remains under debate,however,many studies suggest toxicity,especially from mercury(Hg),in individuals diagnosed with an ASD.The present study evaluated concerns about the toxic effects of organic-Hg exposure from Thimerosal(49.55%Hg by weight)in childhood vaccines by conducting a two-phased(hypothesis generating/hypothesis testing)study with documented exposure to varying levels of Thimerosal from vaccinations.Methods:A hypothesis generating cohort study was undertaken to evaluate the relationship between exposure to organic-Hg from a Thimerosal-containing Diphtheria-Tetanus-acellular-Pertussis(DTaP)vaccine in comparison to a Thimerosal-free DTaP vaccine administered,from 1998 through 2000,for the risk of ASD as reported in the Vaccine Adverse Event Reporting System(VAERS)database(phase I).A hypothesis testing case–control study was undertaken to evaluate the relationship between organic-Hg exposure from Thimerosal-containing hepatitis B vaccines administered at specific intervals in the first six months of life among cases diagnosed with an ASD and controls born between 1991 through 1999 in the Vaccine Safety Datalink(VSD)database(phase II).Results:In phase I,it was observed that there was a significantly increased risk ratio for the incidence of ASD reported following the Thimerosal-containing DTaP vaccine in comparison to the Thimerosal-free DTaP vaccine.In phase II,it was observed that cases diagnosed with an ASD were significantly more likely than controls to receive increased organic-Hg from Thimerosal-containing hepatitis B vaccine administered within the first,second,and sixth month of life.Conclusions:Routine childhood vaccination is an important public health tool to reduce the morbidity and mortality associated with infectious diseases,but the present study provides new epidemiological evidence supporting an association between increasing organic-Hg exposure from Thimerosal-containing childhood vaccines and the subsequent risk of an ASD diagnosis. | David A Geier Brian S Hooker Janet K Kern Paul G King Lisa K Sykes Mark R Geier | 2013 | Translational Neurodegeneration2013，2，1： | 1 |
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