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| 1 | Chemical vapor deposition of monolayer WS2 nano- sheets on Au foils toward direct application in hydrogen evolution显示文摘Monolayer tungsten disulfide (WS2), a typical member of the semiconducting transition metal dichalcogenide family has drawn considerable interest because of its unique properties. Intriguingly the edge of WS2 exhibits an ideal hydrogen binding energy which makes WS2 a potential alternative to Pt-based electrocatalysts for the hydrogen evolution reaction (HER). Here, we demonstrate for the first time the successful synthesis of uniform monolayer WS2 nanosheets on centimeter- scale Au foils using a facile, low-pressure chemical vapor deposition method. The edge lengths of the universally observed triangular WS2 nanosheets are tunable from -100 to N1,000 nm. The WS2 nanosheets on Au foils featuring abundant edges were then discovered to be efficient catalysts for the HER, exhibiting a rather high exchange current density of -30.20 μA/cm2 and a small onset potential of Nl10 mV. The effects of coverage and domain size (which correlate closely with the active edge density of WS2) on the electrocatalytic activity were investigated. This work not only provides a novel route toward the batch-production of monolayer WS2 via the introduction of metal foil substrates but also opens up its direct application for facile HER. | Yanshuo Zhang Jianping Shi Gaofeng Han Minjie Li Qingqing Ji Donglin Ma Yu Zhang Cong Li Xingyou Lang Yanfeng Zhang Zhongfan Liu | 2015 | Nano Research2015，8，9： | 7 |
| 2 | Pirh2 mediates the sensitivity of myeloma cells to bortezomib via canonical NF-κB signaling pathway显示文摘 | Li Yang Jing Chen Xiaoyan Han Enfan Zhang Xi Huang Xing Guo Qingxiao Chen Wenjun Wu Gaofeng Zheng Donghua He Yi Zhao Yang Yang Jingsong He Zhen Cai | 2018 | Protein & Cell2018，9，9： | 3 |
| 3 | Tuning charge density of chimeric antigen receptor optimizes tonic signaling and CAR-T cell fitness显示文摘Tonic signaling of chimeric antigen receptor(CAR),i.e.,the spontaneous CAR activation in the absence of tumor antigen stimulation,is considered to be a pivotal event controlling CAR-T efficacy.However,the molecular mechanism underlying the spontaneous CAR signals remains elusive.Here,we unveil that positively charged patches(PCPs)on the surface of the CAR antigenbinding domain mediate CAR clustering and result in CAR tonic signaling.For CARs with high tonic signaling(e.g.,GD2.CAR and CSPG4.CAR),reducing PCPs on CARs or boosting ionic strength in the culture medium during ex vivo CAR-T cell expansion minimizes spontaneous CAR activation and alleviates CAR-T cell exhaustion.In contrast,introducing PCPs into the CAR with weak tonic signaling,such as CD19.CAR,results in improved in vivo persistence and superior antitumor function.These results demonstrate that CAR tonic signaling is induced and maintained by PCP-mediated CAR clustering.Notably,the mutations we generated to alter the PCPs maintain the antigen-binding affinity and specificity of the CAR.Therefore,our findings suggest that the rational tuning of PCPs to optimize tonic signaling and in vivo fitness of CAR-T cells is a promising design strategy for the nextgeneration CAR. | Jian Chen Shizhen Qiu Wentao Li Kun Wang Yu Zhang Han Yang Baichuan Liu Guangfei Li Li Li Min Chen Junjie Lan Jiahua Niu Peijie He Lei Cheng Gaofeng Fan Xin Liu Xianmin Song Chenqi Xu Haitao Wu Haopeng Wang | 2023 | Cell Research2023，33，5： | 2 |
| 4 | Productivity and economic growth in east Asia:innovation,efficiency and accumulation显示文摘 | Gaofeng Han Kalirajan K Singh N | 2004 | Journal of Developing Areas2004，37，2： | 1 |
| 5 | Den- dritic,transferable,strictly monolayer MoS2 flakes synthesized on SrTiO3 single crystals for efficient elec- trocatalytic applications显示文摘 | ZHANG Yu JI Qingqing HAN Gaofeng | 2014 | ACS Nano2014，8，8： | 1 |
| 6 | Con- trollable growth and transfer of monolayer MoS2 on Au foils and its potential application in hydrogen evolution reaction显示文摘 | SHI Jianping MA Donglin HAN Gaofeng | 2014 | ACS Nano2014，8，10： | 1 |
| 7 | Department of internal medicine nursing work in cardiovascular prevention and management of unsafe factors 显示文摘 | Han Gaofeng | 2011 | Chinese and foreign women and children''s health2011，19，4： | 1 |
| 8 | Biotransfer of persistent organic pollutants from a large site in China used for the disassembly of electronic and electrical waste显示文摘 | Gaofeng Zhao Ying Xu Guanggen Han Bo Ling | 2006 | Environmental Geochemistry and Health2006，，4： | 1 |
| 9 | Productivity and economic growth in East Asia: innovation, efficiency and accumulation显示文摘 | Gaofeng Han Kaliappa Kalirajan Nirvikar Singh | 2002 | Japan & The World Economy2002，，4： | 1 |
| 10 | Achievements and Prospects of Wind Power Prediction显示文摘Wind power prediction is crucial to the operation of the power system accommodating a large amount of wind power. From the perspective of power dispatch, this paper discusses the current situations of the technology, system building, prediction errors, the index for evaluating wind power prediction system and the main bodies responsible for the prediction. It delves into the existing problems such as incomplete basic data, poor prediction accuracy, short prediction time scale, as well as lacking of prediction in most wind farms. Suggestions on improvement are proposed including enhancing the construction of wind power prediction system on both the grid side and the wind farm side, speeding up the development of ultra-short term wind power prediction system, deepening the research on wind power prediction technology, strengthening the construction of technical standard system and carrying out cross-sector cooperation. | Fan Gaofeng, Pei Zheyi, Xin Yaozhong National Power Dispatching & Communication Center Han Ruiguo | 2011 | Electricity2011，22，5： | 0 |
| 11 | High levels of serum IL-10 indicate disease progression,extramedullary involvement,and poor prognosis in multiple myeloma显示文摘Multiple myeloma(MM)is a common malignant hematological tumor in adults,which is characterized by clonal malignant proliferation of plasma cells in the bone marrow and secretion of a large number of abnormal monoclonal immunoglobulins(M protein),leading to bone destruction,hypercalcemia,anemia,and renal insufficiency(Alexandrakis et al.,2015;Yang et al.,2018).Since a large number of new drugs,represented by proteasome inhibitors and immunomodulators,have been successfullyused to treat MM. | Xiaoyan YUE Linlin HUANG Yang YANG Yi ZHAO Donghua HE Xiaoyan HAN Gaofeng ZHENG Yi LI Enfan ZHANG Zhen CAI Xin HUANG Jingsong HE | 2022 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2022，23，11： | 0 |
| 12 | Neutrophil membrane-camouflaged nanoparticles alleviate inflammation and promote angiogenesis in ischemic myocardial injury显示文摘Acute myocardial infarction(AMI)induces a sterile inflammatory response,leading to cardiomyocyte damage and adverse cardiac remodeling.Interleukin-5(IL-5)plays an essential role in developing eosinophils(EOS),which are beneficial for the resolution of inflammation.Furthermore,the proangiogenic properties of IL-5 also contribute to tissue healing following injury.Therefore,targeted delivery of IL-5 is an innovative therapeutic approach for treating AMI.It has been shown that conventional IL-5 delivery can result in undesirable adverse effects and potential drug overdose.In this study,we successfully synthesized a biomimetic IL-5 nanoparticle by camouflaging the IL-5 nanoparticle in a neutrophilic membrane.The administration of neutrophil membrane-camouflaged nanoparticles(NM-NPIL-5)in the in vivo model showed that these nanoparticles promoted EOS accumulation and angiogenesis in the infarcted myocardium,thereby limiting adverse cardiac remodeling after AMI.Our results also demonstrated that the NM-NPIL-5 could serve as neutrophil“decoys”to adsorb and neutralize the elevated neutrophil-related cytokines in the injured heart by inheriting multiple receptors from their“parent”neutrophils.Finally,the targeted delivery of NM-NPIL-5 protected the cardiomyocytes from excessive inflammatory-induced apoptosis and maintained cardiac function.Our findings provided a promising cardiac detoxification agent for acute cardiac injury. | Dongjian Han Fuhang Wang Zhentao Qiao Bo Wang Yi Zhang Qingjiao Jiang Miaomiao Liu Yuansong Zhuang Quanxu An Yan Bai Jiahong Shangguan Jinying Zhang Gaofeng Liang Deliang Shen | 2023 | Bioactive Materials2023，，5： | 0 |
| 13 | Liquidity of China’s government bond market: Measures and driving forces显示文摘We construct a daily liquidity index of China’s government bond market using transaction data from the national interbank market during 2001–2020.The index is a composite of popular price-based and quantity-based metrics of liquidity.The composite indices,ob-tained by averaging across different metrics and by applying the principal component analysis,respectively,both point to a better liquidity condition after 2010.Market liquidity swings appear to be highly correlated with domestic funding liquidity and financial mar-ket volatility,but display fewer correlations with global macrofinan-cial indicators.Our findings suggest that the further deepening of the government bond market would support domestic financial stability and monetary operations down the road. | Gaofeng Han Hui Miao Yabin Wang | 2023 | Economic and Political Studies2023，11，1： | 0 |
| 14 | Construction of Synergistic Co and Cu Diatomic Sites for Enhanced Higher Alcohol Synthesis显示文摘Higher alcohol synthesis(HAS)from syngas could efficiently alleviate the dependence on the traditional fossil resources.However,it is still challenging to construct high-performance HAS catalysts with satisfying selectivity,space–time yield(STY),and stability.Herein,we designed a diatomic catalyst by anchoring Co and Cu sites onto a hierarchical porous N-doped carbon matrix(Co/Cu–N–C).The Co/Cu–N–C is efficient for HAS and is among the best catalysts reported.With a COconversion of 81.7%,C2+OHselectivity could reach 58.5%with an outstanding C2+OH STY of 851.8 mg/g·h.We found that the N4–Co1 and Cu1–N4 showed an excellent synergistic effect.The adsorption of CO occurred on the Co site,and the surrounding nitrogen sites served as a hydrogen reservoir for the CO reduction reactions to form CHxCo.Meanwhile,the Cu sites stabilized a CHOCu species to interact with CHxCo,facilitating a barrier-free formation of C2 species,which is responsible for the high selectivity of higher alcohols. | Gaofeng Chen Olga A.Syzgantseva Maria A.Syzgantseva Shuliang Yang Guihua Yan Li Peng Changyan Cao Wenxing Chen Zhiwei Wang Fengjuan Qin Tingzhou Lei Xianhai Zeng Lu Lin Weiguo Song Buxing Han | 2023 | CCS Chemistry2023，5，4： | 0 |
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