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| 1 | Achieving the best bowel preparation for colonoscopy显示文摘Bowel preparation is a core issue in colonoscopy,as it is closely related to the quality of the procedure.Patients often find that bowel preparation is the most unpleasant part of the examination.It is widely accepted that the quality of cleansing must be excellent to facilitate detecting neoplastic lesions.In spite of its importance and potential implications,until recently,bowel preparation has not been the subject of much study.The most commonly used agents are high-volume polyethylene glycol(PEG)electrolyte solution and sodium phosphate.There has been some confusion,even in published meta-analyses,regarding which of the two agents provides better cleansing.It is clear now that both PEG and sodium phosphate are effectivewhen administered with proper timing.Consequently,the timing of administration is recognized as one of the central factors to the quality of cleansing.The bowel preparation agent should be administered,at least in part,a few hours in advance of the colonoscopy.Several low volume agents are available,and either new or modified schedules with PEG that usually improve tolerance.Certain adjuvants can also be used to reduce the volume of PEG,or to improve the efficacy of other agents.Other factors apart from the choice of agent can improve the quality of bowel cleansing.For instance,the effect of diet before colonoscopy has not been completely clarified,but an exclusively liquid diet is probably not required,and a low-fiber diet may be preferable because it improves patient satisfaction and the quality of the procedure.Some patients,such as diabetics and persons with heart or kidney disease,require modified procedures and certain precautions.Bowel preparation for pediatric patients is also reviewed here.In such cases,PEG remains the most commonly used agent.As detecting neoplasia is not the main objective with these patients,less intensive preparation may suffice.Special considerations must be made for patients with inflammatory bowel disease,including safety and diagnostic issues,so that the most adequate agent is chosen.Identifying neoplasia is one of the main objectives of colonoscopy with these patients,and the target lesions are often almost invisible with white light endoscopy.Therefore excellent quality preparation is required to find these lesions and to apply advanced methods such as chromoendoscopy.Bowel preparation for patients with lower gastrointestinal bleeding represents a challenge,and the strategies available are also reviewed here. | Adolfo Parra-Blanco Alex Ruiz Manuel Alvarez-Lobos Ana Amorós Juan Cristóbal Gana Patricio Ibáez Akiko Ono Takahiro Fujii | 2014 | World Journal of Gastroenterology2014，20，47： | 37 |
| 2 | Management of Helicobacter pylori infection in Latin America: A Delphi technique-based consensus显示文摘AIM: To optimize diagnosis and treatment guidelines for this geographic region, a panel of gastroenterologists, epidemiologists, and basic scientists carried out a structured evaluation of available literature.METHODS: Relevant questions were distributed among the experts, who generated draft statements for consideration by the entire panel. A modified three-round Delphi technique method was used to reach consensus. Critical input was also obtained from representatives of the concerned medical community. The quality of the evidence and level of recommendation supporting each statement was graded according to United States Preventive Services Task Force criteria.RESULTS: A group of ten experts was established. The survey included 15 open-ended questions that were distributed among the experts, who assessed the articles associated with each question. The levels of agreement achieved by the panel were 50% in the first round, 73.3% in the second round and 100% in the third round. Main consensus recommendations included:(1) when available, urea breath and stool antigen test(HpSA) should be used for non-invasive diagnosis;(2) detect and eradicate Helicobacter pylori(H. pylori) in all gastroscopy patients to decrease risk of peptic ulcer disease, prevent o retard progression in patients with preneoplastic lesions, and to prevent recurrence in patients treated for gastric cancer;(3) further investigate implementation issues and health outcomes of H. pylorieradication for primary prevention of gastric cancer in high-risk populations;(4) prescribe standard 14-d triple therapy or sequential therapy for first-line treatment;(5) routinely assess eradication success post-treatment in clinical settings; and(6) select second- and third-line therapies according to antibiotic susceptibility testing.CONCLUSION: These achievable steps toward better region-specific management can be expected to improve clinical health outcomes. | Antonio Rollan Juan Pablo Arab M Constanza Camargo Roberto Candia Paul Harris Catterina Ferreccio Charles S Rabkin Juan Cristóbal Gana Pablo Cortés Rolando Herrero Luisa Durán Apolinaria García Claudio Toledo Alberto Espino Nicole Lustig Alberto Sarfatis Catalina Figueroa Javier Torres Arnoldo Riquelme | 2014 | World Journal of Gastroenterology2014，20，31： | 2 |
| 3 | Kinetics of the acidic and enzymatic hydrolysis of benazepril HCI studied by LC 显示文摘 | GANA M PANDERI I PARISSI-POULOU A | 2002 | J Pharm Biomed Anal2002，27，12： | 1 |
| 4 | Winterhardiness,root physiology and gene expression in successive fall dormancy selections from 'Mesilla'and 'CUF101'alfalfa显示文摘 | CUNNINGAM S M GANA J A VOLENEC J J | 2001 | Crop Sci2001，41，： | 1 |
| 5 | Intercropping study in sugarcane 显示文摘 | GANA A K BUSARI L D | 2003 | Sugarcane Technology2003，5，3： | 1 |
| 6 | Final steps of nicotine in the catabolism of nicotine deamination versus demethylation of ~-N - methylaminobutyrate 显示文摘 | Calin-Bogdan Chiribau Marius Mihasan Petra Ganas | 2006 | FEBS Journal2006，273，： | 1 |
| 7 | Lung volumes 24h after laparoscopic cholecystectomy-justification for early discharge显示文摘 | Ali J Gana TJ | 1998 | Can Respir J1998，5，2： | 1 |
| 8 | Pattern of mechanical intestinal obstruction in Ibadan: a ten year review显示文摘 | Shittu OB Gana JY Alawale EO | 2001 | Aft J Med Sei2001，30，12： | 1 |
| 9 | pH in expired breath condensate of patients with inflammatory airway diseases显示文摘 | KOSTIKAS K PAPATHEODOROU G GANAS K | 2002 | Am J Resp Crit Care Med2002，165，10： | 1 |
| 10 | Optimal policy and stability regions for the single product periodic review inventory problem, with stationary demands显示文摘 | PAPACHRISTOS S GANAS I | 1998 | The Journal of the Operational Research Society1998，49，2： | 1 |
| 11 | The single-product lot-sizing problem with constant parameters and backlogging: exact results,a new solution, and all parameter stability regions显示文摘 | GANAS I PAPACHRISTOS S | 2005 | Operations Research2005，53，1： | 1 |
| 12 | pH in expired breath condensate of patients with inflammatory airway diseases显示文摘 | Kostikas K Papatheodorou G Ganas K | 2002 | Am J Respir Crit Care Med2002，165，： | 1 |
| 13 | Early Postoperative Bioprosthetic Valve Calcification显示文摘 | Anand Iyer Paras Malik Ramesh Prabha Gana Kugathasan Opeyemi Kuteyi Lucy Marney Robert Larbalestier | 2013 | Heart, Lung and Circulation2013，，： | 1 |
| 14 | Pattern of mechanical intestinal obstruction in ibadan:a ten year review显示文摘 | Shittu OB Gana JY Alawale EO | 2001 | Afr J Med Med Sci2001，30，12： | 1 |
| 15 | Isolation and characterization of halophilic archaea able to produce bio- surfactants 显示文摘 | Kebbouche G Gana M Khemili S | 2009 | Journal of Industrial Microbiology Biotech- nology2009，36，5： | 1 |
| 16 | Pattern of mechanical intestinal tuberculosis in Ibadan;a ten-year review显示文摘 | Shittu OB Gana JY Alawale EO | 2001 | Afr J Med Sci2001，30，12： | 1 |
| 17 | Influence of manganese rate on structural, optical and electrochemical properties of CeO_(2) thin films deposited by spray pyrolysis:Supercapacitor applications显示文摘The present work aimed to investigate the electrochemical properties of ITO substrates in propylene carbonate(PC) with 0.5 mol/L lithium perchlorate(LiClO_(4)) medium in the presence of elaborated thin films of cerium dioxide pure and doped with manganese at varying percentages.Ce_(1-x)Mn_(x)O_(2)(x=0 wt%,2 wt%,4 wt% and 6 wt%) were successfully deposited by the spray pyrolysis(SP) technique on the glass substrate and ITO at 450℃.The effects of manganese(Mn) doped thin films Ce_(1-x)Mn_(x)O_(2) were studied and investigated by using different analyses namely X-ray diffraction(XRD) analysis,Raman spectroscopy method,UV-Vis spectrophotometer technique,atomic force microscopy(AFM) analysis and electrochemical properties.XRD data obtained present a polycrystalline with a face-centred cubic structure of fluorite type.Raman results of undoped and Mn doped thin films show two peaks at 465 and 600 cm^(-1),due to the formation of extrinsic oxygen vacancies by the incorporation of Mn into Ce1-xMnxO_(2) matrix.Energy dispersive spectroscopy(EDS) data show the presence of Ce,O,and Mn elements in the elaborated films.The AFM results reveal that the surface roughness decreases with increasing Mn rate.Further,band gap energy of thin films decreases with increasing in Mn rate due to the formation of defect state between valence and conduction band.The storage capacity of the elaborated Ce_(1-x)Mn_(x)O_(2)/ITO/PC+LiClO_(4) electrode reaches a maximum of 1.997 mF in the presence of 6 wt% of Mn. | J.Zimou K.Nouneh A.Talbi L.El Gana A.El-Habib R.Hsissou M.Addou | 2022 | Journal of Rare Earths2022，40，10： | 1 |
| 18 | Prospective evaluation of safety and tolerance of colonoscopy in children 显示文摘 | Gana AJC Glenz AC Marchant AP | 2006 | Rev Med Chil2006，134，5： | 1 |
| 19 | Inventory models withramp type demand rate, partial backlogging and Weibull deterioration rate显示文摘 | Skouri K Konstantaras I Papachristos S Ganas I | 2009 | European Journal of Operational Research2009，192，1： | 1 |
| 20 | Predictors of fetal mortality in pregnanttrauma patients 显示文摘 | Ali J Yeo A Gana TJ | 1997 | J Trauma1997，42，5： | 1 |
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