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| 1 | Early palliative care for patients with metastatic non-small-cell lung cancer显示文摘Comments This landmark article demonstrates that integration of early palliative care with standard oncologic practice shortly after diagnosis may improve quality of life,mood,and overall survival for adults with advanced non-small-cell lung cancer(NSCLC).If validated,these findings could support a paradigm shift in the care of adults with metastatic NSCLC and possibly patients with other tumor types characterized by short survival and high symptom burden. | Temel JS Greer JA Muzikansky A Gallagher ER Admane S Jackson VA Dahlin CM Blinderman CD Jacobsen J Pirl WF Billings JA Lynch TJ | 2010 | 中国肺癌杂志2010，13，9： | 165 |
| 2 | 探索MOOC教学方法在mLearning中的运用显示文摘本文把大型开放式网络课程(Massively Open Online Course,以下简称MOOC)作为适应移动学习(mLearning)的一种可能的教学方法,这种教学方法建立在与当前学习或教学形式相适宜的基础上。本文呈现了一个MobiMOOC应用的案例研究,该案例使用MOOC形式创建一门课程,研究展示了MOOC和mLearning之间的协同特性,并将当前数字化的协作学习和知识建构这两个理想领域结合在一起。MobiMOOC是聚焦于mlearning、为期六周的网上课程,于2011年的4月到5月之间进行。MobiMOOC是免费开放的课程,有556位学习者加入了课程谷歌群组。课程结束时的调查结果有力地证明了MOOCs和mLearning之间的协同作用。本篇论文对时间和地点的独立性、情境学习、协作学习、潜在的跨学科信息交流,以及应用于网上学习的技术,如社交媒体,移动设备等方面进行了探讨。 | Inge DE Waard Apostolos Koutropoulos Nilgün zdamar Keskin Sean C.Abajian Rebecca Hogue C.Osvaldo Rodriguez Michael Sean Gallagher 何伏刚 马东明 孙海民 | 2012 | 中国远程教育2012，，5： | 39 |
| 3 | 纽约中央公园150年演进历程显示文摘文章以纪实的方法,在纽约社会、经济和政治的时代背景中,勾勒出一条清晰的发展脉络,详实而生动地叙述了中央公园150年的变迁。从兴建议案的提出,到设计方案的产生,以及随着公园的兴建和改建而发生的重要事件,都交织在公园本身建造意图的体现和人们对公园的态度之中,从而使我们看到在纽约这个高密度的喧嚣都市中,还有这样一方极尽关怀和体现人的价值的、具有丰富历史和社会内涵的城市环境。 | Witold Rybczynski 陈伟新 Michael Gallagher | 2004 | 国外城市规划2004，19，2： | 21 |
| 4 | Risk factors for complications after ERCP: a multivariate analysis of 11,497 procedures over 12 years显示文摘 | Peter B. Cotton Donald A. Garrow Joseph Gallagher Joseph Romagnuolo | 2009 | Gastrointestinal Endoscopy2009，，1： | 7 |
| 5 | 不同人种绝经后全身与局部脂肪分布的改变情况显示文摘目的为了验证脂肪中心性分布的人种因素;确定白人、黑人与亚洲妇女绝经后脂肪中心性分布的不同。方法横断面研究,通过双能X线吸收法测量全身与局部的脂肪含量并进行线性回归分析。募集了444名,年龄18~94岁的妇女,其中227名白人,128名黑人与89名亚洲人。通过对年龄、体重、身高与全身脂肪校正后,分析男性型与女性型脂肪的分布与躯干/四肢脂肪的比值。结果种族因素与男性型、女性型脂肪及躯干/下肢脂肪比值显著相关(P〈0.O001)。种族-绝经也发现有显著意义(P=0.028)。每一组,局部与全身脂肪水平,特别是男性型脂肪在绝经后妇女中高于绝经前妇女。而且,绝经后男性型脂肪分布在白人有显著意义(P〈0.05),但在黑人与亚洲人中无影响。结论脂肪量与其分布主要由人种决定。绝经的影响在白人中具有显著意义。 | 孙爱军 Dympna Gallagher Richard N. PiersonJr. | 2007 | 生殖医学杂志2007，16，6： | 6 |
| 6 | 老年人处方遗漏筛查工具第2版(中文版)显示文摘近年来我国老年人口数量迅速增加,2013年老年人口突破2亿大关。老年人常伴有多种疾病且同时服用多种药物,容易出现药物相互作用和药物不良反应,所以老年人用药问题是医务人员关注的重点。老年人不适当用药问题主要包括两个方面:老年人需要避免使用的药物和老年人需要使用而未使用的药物。 | Denis O'Mahony David O'Sullivan Stephen Byrne Marie Noelle O'Connor Cristin Ryan Paul Gallagher 侯凯旋 邢晓璇 闫素英 | 2017 | 药物不良反应杂志2017，19，5： | 4 |
| 7 | Short-Root1 Plays a Role in the Development of Vascular Tissue and Kranz Anatomy in Maize Leaves显示文摘 | Thomas L. Slewinski Alyssa A. Anderson Simara Price Jacob R. Withee Kimberly Gallagher Robert Turgeon | 2014 | Molecular Plant2014，7，8： | 4 |
| 8 | Diagnostic Accuracy of Noninvasive Coronary Angiography Using 64-Slice Spiral Computed Tomography显示文摘 | Gilbert L. Raff Michael J. Gallagher William W. O’Neill James A. Goldstein | 2005 | Journal of the American College of Cardiology2005，，3： | 3 |
| 9 | Reliable and explainable machine-learning methods for accelerated material discovery显示文摘Despite ML’s impressive performance in commercial applications,several unique challenges exist when applying ML in materials science applications.In such a context,the contributions of this work are twofold.First,we identify common pitfalls of existing ML techniques when learning from underrepresented/imbalanced material data.Specifically,we show that with imbalanced data,standard methods for assessing quality of ML models break down and lead to misleading conclusions.Furthermore,we find that the model’s own confidence score cannot be trusted and model introspection methods(using simpler models)do not help as they result in loss of predictive performance(reliability-explainability trade-off).Second,to overcome these challenges,we propose a general-purpose explainable and reliable machine-learning framework.Specifically,we propose a generic pipeline that employs an ensemble of simpler models to reliably predict material properties.We also propose a transfer learning technique and show that the performance loss due to models’simplicity can be overcome by exploiting correlations among different material properties.A new evaluation metric and a trust score to better quantify the confidence in the predictions are also proposed.To improve the interpretability,we add a rationale generator component to our framework which provides both model-level and decision-level explanations.Finally,we demonstrate the versatility of our technique on two applications:(1)predicting properties of crystalline compounds and(2)identifying potentially stable solar cell materials.We also point to some outstanding issues yet to be resolved for a successful application of ML in material science. | Bhavya Kailkhura Brian Gallagher Sookyung Kim Anna Hiszpanski T.Yong-Jin Han | 2019 | npj Computational Materials2019，，1： | 3 |
| 10 | MRI of pituitary abscess: two cases and review of the literature 显示文摘 | Wolansky LJ Gallagher JD Heary RF | 1997 | Neuroradiology1997，39，7： | 3 |
| 11 | Appropriate prescribing in the elderly: Current perspectives显示文摘Advances in medical therapeutics have undoubtedly contributed to health gains and increases in life expectancy over the last century. However, there is growing evidence to suggest that therapeutic decisions in older patients are frequently suboptimal or potentially inappropriate and often result in negative outcomes such as adverse drug events, hospitalisation and increased healthcare resource utilisation. Several factors influence the appropriateness of medication selectionin older patients including age-related changes in pharmacokinetics and pharmacodynamics, high numbers of concurrent medications, functional status and burden of co-morbid illness. With ever-increasing therapeutic options, escalating proportions of older patients worldwide, and varying degrees of prescriber education in geriatric pharmacotherapy, strategies to assist physicians in choosing appropriate pharmacotherapy for older patients may be helpful. In this paper, we describe important age-related pharmacological changes as well as the principal domains of prescribing appropriateness in older people. We highlight common examples of drugdrug and drug-disease interactions in older people. We present a clinical case in which the appropriateness of prescription medications is reviewed and corrective strategies suggested. We also discuss various approaches to optimising prescribing appropriateness in this population including the use of explicit and implicit prescribing appropriateness criteria, comprehensive geriatric assessment, clinical pharmacist review, prescriber education and computerized decision support tools. | Amanda Hanora Lavan John O'Grady Paul Francis Gallagher | 2015 | World Journal of Pharmacology2015，4，2： | 3 |
| 12 | BRAF inhibitor treatment of melanoma causing colonic polyps:An alternative hypothesis显示文摘Colonic polyps may arise from BRAF inhibitor treatment of melanoma, possibly due paradoxical activation of the mitogen-activated protein(MAP)-kinase pathway. In an alternative evidence based scenario, tubular colonic adenomas with APC gene mutations have also been identified in the context of BRAF inhibitor treatment, in the absence of mutations of MAPK genes. A minority of colorectal cancers develop by an alternative 'serrated polyp pathway'. This article postulates a novel hypothesis, that the established phenotypic and molecular characteristics of serrated colonic polyps/CRC offer an intriguing insight into the pathobiology of BRAF inhibitor induced colonic polyps. Serrated polyps are characterized by a Cp G island methylation phenotype, MLH1 silencing and cellular senescence. They also have BRAF mutations. The contention is that BRAF inhibitor induced polyps mimic the afore-described histology and molecular features of serrated polyps with the exception that instead of the presence of BRAF mutations they induce C-RAF homodimers and B-RAF: C-RAF heterodimers. | Fergal C Kelleher Grainne Callaghan Catriona Gallagher Hazel O'Sullivan | 2017 | World Journal of Gastroenterology2017，23，17： | 2 |
| 13 | Anxiety in patients undergoing percutaneous coronary interventions显示文摘 | Renée Trotter Robyn Gallagher Judith Donoghue | 2011 | Heart & Lung - The Journal of Acute and Critical Care2011，，3： | 2 |
| 14 | Potent vasodilator responses to human urotensin Ⅱ in human pulmonary and abdominal resistance arteries显示文摘 | Stirrat A Gallagher M Douglas S A | 2001 | Am J Physiol Heart Cire Physiol2001，280，2： | 2 |
| 15 | WONCA研究论文摘要汇编——社区医疗中用药错误存在问题及解决办法的重要性分级:一项基于重要性排列法促进用药安全的研究显示文摘背景用药错误的研究主要集中在医院内。本文旨在研究社区医疗中的用药错误,调查引起用药错误的主要原因并提出相关的解决办法。方法 2013年9月—2014年11月,使用重要性排列法对用药错误存在问题及解决办法进行确定和分级。500位来自伦敦西北部的社区医师参加了开放式问卷调查,回收有效问卷113份,存在问题有48个,相关解决办法有45种。从500位社区医师中随机抽选57位,对存在问题及解决办法进行评分,并根据评分情况,列出用药错误存在问题及解决办法的重要性级别表。结果前3个存在问题是:给患者开药的不同的医生在用药方面的看法不完全一致性,不适当的用药指导以及质量较差的出院总结。前3个解决办法是:设计标准的出院总结模板,减少不必要的处方以及最大限度的减少多药疗法。结论社区医师在用药管理、用药流程质量控制及用药指导方面给出了一系列建议。认为,这些可行的负担得起的干预方式在很大程度上可以预防用药错误的发生。 | TUDOR CAR L PAPACHRISTOU N GALLAGHER J 本刊编辑部 | 2017 | 中国全科医学2017，20，2： | 2 |
| 16 | Current management of adrenal tumors显示文摘 | Rajesh Kuruba Scott F Gallagher | 2008 | Current Opinion in Oncology2008，，1： | 2 |
| 17 | Intra‐operative transanal near infrared imaging of colorectal anastomotic perfusion: a feasibility study显示文摘 | D. A. Sherwinter J. Gallagher T. Donkar | 2012 | Colorectal Disease2012，，1： | 2 |
| 18 | The effects of traditional antidiabetic plants on in vitro glucose diffusion显示文摘 | A.M Gallagher P.R Flatt G Duffy Y.H.A Abdel-Wahab | 2003 | Nutrition Research2003，，3： | 2 |
| 19 | 美国东南部5年生桉树能源林生长规律及耐寒性分析显示文摘为应对美国南部生物新能源市场的兴起,评估边沁桉(Eucalyptus benthamii)供应市场的能力,对边沁桉人工林生长参数及其抗寒性能进行了试验研究。试验种植了两种不同密度(1 650棵/hm2和1237棵/hm2)的桉树林并连续5 a进行观测分析。结果表明:幼年期的边沁桉个体生长具有显著差异性。5年生桉树最大胸径和最小胸径分别为27.9 cm和1.27cm;最大高度和最小高度分别为22.86 m和2.44 m;桉树胸径和树高的年增长也具有显著差异性。两种不同密度年存活率也存在差异性,同时影响着树高和胸径的生长。密度为1 650棵/hm2人工林平均胸径和树高分别为11.18 cm和15.03 m。密度为1 237棵/hm^2平均胸径和树高分别为13.46 cm和16.28 m。密度为1 650棵/hm^2和1 237棵hm^2平均每公倾公顷材积分别为111.45 m3和101.15 m^3;平均每年的直径和树高生长分别为2.54 cm和3 m。边沁桉人工林的生长随着生长环境的不同也呈现差异。本次试验人工林中的第1行和第7行就是一个很好的例证。边沁桉的生长受年平均气温的影响不大,但受最低温的限制,一般认为边沁桉能耐受的温度为-7.4℃。 | 余爱华 Tom Gallagher | 2015 | 森林工程2015，31，6： | 2 |
| 20 | Regulation of Kupffer cell TNF gene expression during experimental acute pancreatitis: The role of p38-MAPK, ERK1/2, SAPK/JNK, and NF-κB显示文摘 | Michel M. Murr M.D. Jun Yang M.D. Adam Fier B.A. Scott F. Gallagher M.D. Gay Carter B.A. William R. Gower Ph.D. James G. Norman M.D | 2003 | Journal of Gastrointestinal Surgery2003，，1： | 2 |
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