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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | IL-16 represses HIV-1 promoter activity显示文摘 | Maciaszek JW Parada NA Cruikshank WW Center DM Kornfeld H Viglianti GA | 1997 | J Immunol1997，158，1： | 1 |
| 3 | Isolation of mumps vires from theinner ear after sudden deafness显示文摘 | Westmore GA Pickard BH Stem H | 1979 | Br Med J1979，1，6155： | 1 |
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| 5 | The diagnostic properties of rheumatoid arthritis recognizing a cyclic eitrul-linated peptide 显示文摘 | Schellekens GA Visser H Jong BA | 2005 | Arthritis Rheum2005，43，1： | 1 |
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| 13 | The diagnostic properties of rheumatoid arthritis antibodies recognizing a cyclic citrullinated peptide显示文摘 | Schellekens GA Visser H de Jong BA | | 0，，1： | 1 |
| 14 | Predictive value of selected biochemical markers of brain damage for functional outcome in ischaemic stroke patients显示文摘 | Sienkiewicz-Jarosz H Gaecka-Wolska M Bidziński A | | 0，，： | 1 |
| 15 | Classification of trochanterie fracture of the proximal femur: a study of the reliability of current systems显示文摘 | Pervez H Parker MJ Pryor GA | 2002 | Injury2002，33，8： | 1 |
| 16 | The Canadian CT Head Rule Study for patients with minor head injury: rationale, objectives, and methodology for phase I (derivation) 显示文摘 | Lesiuk H Wells GA | 2001 | Ann E-merg Med2001，38，2： | 1 |
| 17 | Rapamycin induces heme oxygenase-1 in human pulmonary vascular cells:implications in the antiproliferative response to rapamycin显示文摘 | Visner GA Lu F Zhou H | 2003 | Circulation2003，107，6： | 1 |
| 18 | High molecular weight hyaluronan promotes repair of IL-1beta damaged cartilage explants from both young and old bovines显示文摘 | Homandberg GA Ummadi V Kang H | 2003 | Osteoarthritis Cartilage2003，11，3： | 1 |
| 19 | The diagnostic properties of rheumatoid arthritis antibodies recognizing a cyclic citrullinated peptide 显示文摘 | Schellekens GA Visser H de Jong BAW | 2000 | Arthritis Rheum2000，，： | 1 |
| 20 | Improvement in exercise tolerance and symptoms of congestive heart failure during treatment with candesartan cilexetil显示文摘 | Riegger GA Bouzo H Petr P | 1999 | Circulation1999，100，： | 1 |
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