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| 1 | Refined chronology of prehistoric cultures and its implication for re-evaluating human-environment relations in the Hexi Corridor,northwest China显示文摘The reconstruction of high-resolution chronologies for prehistoric cultures is a prerequisite for understanding the history of human evolution and its relationship with environmental change, and is valuable for exploring the trajectory of transcontinental cultural exchanges in prehistoric time. The Hexi Corridor of northwest China was one of the earliest centers for long-distance culture exchange in the prehistoric world. The timing and sequence of cultural changes in this area remains poorly understood resulting from the lack of radiometric age control. This paper presents a refined radiocarbon(14 C) chronology to resolve the timing of human occupation and cultural evolution in the Hexi Corridor. Radiocarbon dating of crop remains, which have an annual life cycle, has the advantage of eliminating problems such as the carbon stored in ‘old wood’. As a result,14C dates from crop remains are used to test the validity of the14C dates derived from charcoal, bone and plant remains. The resultant database of ages is modelled using the Bayesian approach. The updated chronology presented in this paper shows generally good agreement with the original dates used to constrain cultural evolution in the Hexi Corridor. However, the occupation of the corridor by the Shajing and Shanma Late Bronze Age-Early Iron Age cultures appears to have taken place ~300 years later than previously thought. On the basis of comparing this updated chronology of cultural evolution with palaeoclimatic and historical records, it is proposed that the collapse of the Shajing and Shanma cultures occurred as a result of geopolitical impact rather than climate change. | Yishi YANG Shanjia ZHANG Chris OLDKNOW Menghan QIU Tingting CHEN Haiming LI Yifu CUI Lele REN Guoke CHEN Hui WANG Guanghui DONG | 2019 | Science China Earth Sciences2019，62，10： | 5 |
| 2 | Edge analysis and identifica-tion using the continuous shearlet transform 显示文摘 | GUOK LABATE D UM W | 2009 | Applied andComputational Harmonic Analysis2009，27，1： | 1 |
| 3 | Advance Reservation Frameworks in Hybrid 1P-WDM Networks 显示文摘 | Charbonneau N Vokkarane V M Chin Guok | 2011 | IEEE Communications Magazine (S0163-6804)2011，49，5： | 1 |
| 4 | Formulation of pH-responsive PEGylated nanoparticles with high drug loading capacity and programmable drug release for enhanced antibacterial activity显示文摘In the current global crisis of antibiotic resistance,delivery systems are emerging to combat resistant bacteria in a more efficient manner.Despite the significant advances of antibiotic nanocarriers,many challenges like poor biocompatibility,premature drug release,suboptimal targeting to infection sites and short blood circulation time are still challenging.To achieve targeted drug delivery and enhance antibacterial activity,here we reported a kind of pH-responsive nanoparticles by simply self-assembly of an amphiphilic poly(ethylene glycol)-Schiff-vancomycin(PEG-Schiff-Van)prodrug and free Van in one drug delivery system.The acid-liable Schiff base furnished the PEG-Schiff-Van@Van with good storage stability in the neutral environment and susceptible disassembly in response to faintly acidic condition.Notably,on account of the combination of physical encapsulation and chemical conjugation of vancomycin,these nanocarriers with favorable biocompatibility and high drug loading capacity displayed a programmed drug release behavior,which was capable of rapidly reaching high drug concentration to effectively kill the bacteria at an early period and continuously exerting an bacteria-sensitive effect whenever needed over a long period.In addition,more Schiff-base moieties within the PEG-Schiff-Van@Van nanocarriers may also make great contributions on promoting the antimicrobial activity.Using this strategy,this system was designed to have programmable structural destabilization and sequential drug release due to changes in pH that were synonymous with bacterial infection sites,thereby presenting prominent antibacterial therapy both in vitro and in vivo.This work represents a synergistic strategy on offering important guidance to rational design of multifunctional antimicrobial vehicles,which would be a promising class of antimicrobial materials for potential clinical translation. | Dawei Li Guoke Tang Hui Yao Yuqi Zhu Changgui Shi Qiang Fu Fei Yang Xing Wang | 2022 | Bioactive Materials2022，7，10： | 1 |
| 5 | A review of magnesium/magnesium alloys corrosion and its protection 显示文摘 | GUOK | 2010 | Recent Patents Corros Sci2010，2，： | 1 |
| 6 | Nitric oxide-induced downregulation of Cdl2activity and cyclin A gene transcription in vascular smooth muscle cells 显示文摘 | GuoK Andres V Walsh K | 1998 | Circulation1998，97，20： | 1 |
| 7 | The dielectric behavior and efficient microwave absorption of doped nanoscale LaMnO_(3)at elevated temperature显示文摘LaMnO_(3)perovskite has great potential in microwave absorption at high temperature due to its complex doping effect and super stability.The current research mainly focuses on the doping ratio regulation,while the mechanism of doping effect at high temperature is still lack of sufficient investigation.In this work,La1−xSrxMn1−yFeyO_(3)(LaMnO_(3),La_(0.7)Sr_(0.3)MnO_(3),and La_(0.7)Sr_(0.3)Mn_(0.8)Fe_(0.2)O_(3))nanostructures with different doping sites were successfully prepared by the solid phase reaction method.Then,the high temperature dielectric test samples were obtained by mixing with cordierite(2MgO·2Al_(2)O_(3)·5SiO_(2)(MAS)).The results showed that the temperature dependence of Mn ion spin state had a significant impact on the high temperature dielectric behavior of La_(1−x)Sr_(x)Mn_(1−y)FeyO_(3).Particularly,when the thickness is only 1.9 mm,La_(0.7)Sr_(0.3)Mn_(0.8)Fe_(0.2)O_(3)/MAS can achieve the widest bandwidth of 4.2 GHz covered the entire X-band(8.2–12.4 GHz)and a minimum reflection loss(RL)value of−17.99 dB at 500℃.In order to improve the operating temperature of La_(0.7)Sr_(0.3)Mn_(0.8)Fe_(0.2)O_(3)/MAS,a cellular array structure was designed by using computer simulation technology(CST)software to introduce magnetic loss.When the outer length of the hexagon is 1 mm and the coating thickness is 1.9 mm,the widest bandwidth covers the X-band and the minimum RL value is−15.35 dB at 800℃.Therefore,La_(0.7)Sr_(0.3)Mn_(0.8)Fe_(0.2)O_(3)has a great prospect as an efficient high temperature microwave absorber. | Zhigang Mu Guoke Wei Hang Zhang Lu Gao Yue Zhao Shaolong Tang Guangbin Ji | 2022 | Nano Research2022，15，8： | 1 |
| 8 | Nano-scalecopper-coatedgraphiteasanodematerialforlithium-ionbatteries 显示文摘 | Guok Panq Wangl etal | 2002 | Journal of Applied Electrochemistry2002，32，6： | 1 |
| 9 | OnthenewrevisionsofIUCNRedListCategoriesandCriteria显示文摘 | WangXP(王献溥) GuoK(郭柯) | | 植物资源与环境学报0，，： | 1 |
| 10 | Automatic phase-shift method for islanding detection of grid-connected photovoltaic inverters显示文摘 | HUNG GUOK IANG CHANG CH IHANG CHEN CHEMLIN | 2003 | IEEE Trans on Energy Conversion2003，18，1： | 1 |
| 11 | A clinicopathologic and immunohisto-chemieal study of gastrointestinal stromal tumors 显示文摘 | UeyamaT Guok J HasshimotoH | 1992 | Cancer1992，69，： | 1 |
| 12 | Control Plane Architecture and Design Considerations for Multi-Service, Multi-Layer, Multi-Domain Hybrid Networks 显示文摘 | LEHMAN T XI Y GUOK C P | 2008 | IEEE Communications Magazine2008，11，1： | 1 |
| 13 | Improvement of refrigerant capacity of La_(0.67)Ca_(0.33)MnO_(3) single crystal with a few percent Fe doping显示文摘Large low-field-induced magnetic entropy changes, ΔSM, are observed in La0.67Ca0.33MnO3 and La0.67-Ca0.33Mn0.96Fe0.04O3 single crystals. The peaks of ΔSM broadened asymmetrically to high temperatures under higher magnetic fields for two materials should be attributed to the first-order magnetic phase transition at Tc. A small amount of iron doping results in an increase in the refrigerant capacity of the material though the magnetic entropy change decreases. The discovery of excellent magnetocaloric features of these single crystals in the low magnetic field can provide some ideas for exploring novel magnetic refrigerants operating under permanent magnet rather than superconducting one as magnetic field source. | LI GuoKe, ZHANG XiangQun, KOU ZhiQi, LI QingAn, SUN Young & CHENG ZhaoHua State Key Laboratory of Magnetism, Beijing National Laboratory of Condensed Matter Physics and Institute of Physics, Chinese Academy of Sciences, Beijing 100190, China | 2009 | Science China(Physics,Mechanics & Astronomy)2009，52，6： | 0 |
| 14 | pH-responsive delivery of H_(2) through ammonia borane-loaded mesoporous silica nanoparticles improves recovery after spinal cord injury by moderating oxidative stress and regulating microglial polarization显示文摘Imbalance of oxidative and inflammatory regulation is themain contributor to neurofunctional deterioration and failure of rebuilding spared neural networks after spinal cord injury(SCI).As an emerging biosafe strategy for protecting against oxidative and inflammatory damage,hydrogen(H_(2))therapy is a promising approach for improving the microenvironment to allow neural regeneration.However,achieving release of H_(2) at sufficient concentrations specifically into the injured area is critical for the therapeutic effect of H_(2).Thus,we assembled SiO_(2)@mSiO_(2) mesoporous silica nanoparticles and loaded them with ammonia borane(AB),which has abundant capacity and allows controllable release of H_(2) in an acid-dependent manner.The release of H_(2) from AB/SiO_(2)@mSiO_(2) was satisfactory at pH 6.6,which is approximately equal to the microenvironmental acidity after SCI.After AB/SiO_(2)@mSiO_(2) were intrathecally administered to ratmodels of SCI,continuous release of H_(2) fromthese nanoparticles synergistically enhanced neurofunctional recovery,reduced fibrotic scar formation and promoted neural regeneration by suppressing oxidative stress reaction.Furthermore,in the subacute phase of SCI,microglia were markedly polarized toward the M2 phenotype by H_(2) via inhibition of TLR9 expression in astrocytes.In conclusion,H_(2) delivery through AB/SiO_(2)@mSiO_(2) has the potential to efficiently treat SCI through comprehensivemodulation of the oxidative and inflammatory imbalance in themicroenvironment. | Yi Liu Yeying Wang Bing Xiao Guoke Tang Jiangming Yu Weiheng Wang Guohua Xu Xiaojian Ye | 2021 | Regenerative Biomaterials2021，8，6： | 0 |
| 15 | 所享 超乎所想 福建奔驰全新V级豪华多功能车饱含热情而来显示文摘在人们的想象中,MPV常常是严肃和沉闷的,然而梅赛德斯-奔驰的设计师让这种思维定式成为过去——优雅而尊贵,时尚而稳重,福建奔驰全新V级车让驾乘者卓尔不群的个人魅力时刻展现日前福建奔驰汽车工业有限公司正式推出了包括V 260领航版、V 260尊贵版、V 260L尊贵加长版在内的三款全新V级车。全新V级豪华多功能车专属中国,为国内高端人群度身打造。 | Guoke | 2016 | 产品可靠性报告2016，0，6： | 0 |
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