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734篇 您的检索式:作者名="GOLD L"
    题名 作者 年代 出处 被引量
1Tumor mitotic rate,size,and location independently predict recurrence after resection of primary gastrointestinal stromal tumor (GIST)显示文摘Dematteo RP Gold JS Saran L 0,,03:2
2Suppressing tawny crazy ant (Nylanderia fulva) by RNAi technology显示文摘A bstract The tawny crazy ant(Nylanderia fulva)is a new invasive pest in the United States.At present,its management mainly relies on the use of synthetic insecticides,which are generally ineffective at producing lasting control of the pest,necessitating alternative environmentally friendly measures.In this study,we evaluated the feasibility of gene silencing to control this ant species.Six housekeeping genes encoding actin(NfActin),coatomer subunit β (NfCOPP),arginine kinase(NfArgK),and V-type proton ATPase subunits A(NfvATPaseA),B(NfvATPaseB)and E(NfvATPaseE)were cloned.Phylogenetic analysis revealed high sequence similarity to homologs from other ant species,particularly the Florida carpenter ant(Camponotus floridanus).To silence these genes,vector L4440 was used to generate six specific RNAi constructs for bacterial expression.Heat-inactivated,dsRNA-expressing Escherichia coli were incorporated into artificial diet.Worker ants exhibited reduced endogenous gene expression after feeding on such diet for 9 d.However,only ingestion of dsRNAs of NfCOPfi(a gene involved in protein trafficking)and NfArgK(a cellular energy reserve regulatory gene in invertebrates)caused modest but significantly higher ant mortality than the control.These results suggest that bacterially expressed dsRNA can be orally delivered to ant cells as a mean to target its vulnerabilities.Improved efficacy is necessary for the RNAi-based approach to be useful in tawny crazy ant management.Jia Meng Jiaxin Lei Andrew Davitt Jocelyn RHolt Jian Huang Roger Gold Edward L Vargo Aaron MTarone Keyan Zhu-Salzman 2020Insect Science2020,27,1:2
3MethiciHin-resistant staphyloeoccus aureus:comparison of susceptibility testing methods and analysis of mecA positive susceptible strains显示文摘 Gold HS Venkataraman L 2001J Clin Mierobiol2001,39,11:1
4Effects of bolus injection of esmolol in healthy,exercising subjects显示文摘 Carlson L Gold MD 1991Anesth Analg1991,72,:1
5Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary updated 2003显示文摘Fabbri L Pauwels RA Hard SS GOLD Scientific Committee 2004COPD2004,1,1:1
6Cardiac troponin I as a marker for myocardial ischemia in patients seen at the emergency department for acute chest pain 显示文摘Johnson PA Gold man L 1999Am Heart J1999,137,6:1
7Localization and quantitation of expression of the cell motility-related protein thymosin beta15 in human breast tissue显示文摘Gold JS Bao L Ghoussoub RA 1997Mod Pathol1997,10,11:1
8Selection of high a nity RNA ligands to the bacteriophage R17 coat protein显示文摘Schneider D Tuerk C Gold L 1992J Mol Biol1992,228,3:1
9Aptamer-based multiplexed pro- teomic technology for biomarker discovery显示文摘Gold L Ayers D Bertino J 2010PLoS One2010,5,15:1
10Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polynlerase显示文摘Tuerk C Gold L 1990Science1990,249,4968:1
11Alloy optimization for PWR steam generator heat-transfer tubing显示文摘Harrod D L Gold R E Jacko R J 2001JOM2001,53,7:1
12Tumor mitotic rate, size, and location independently predict recurrence after resection of primary gastrointestinal stromal tumor(GIST) 显示文摘Dematteo RP Gold JS Saran L 2008Cancer2008,112,3:1
13Systematic evolution of ligands by exponential enrich-ment: RNA ligands to bacteriophage T4 DNA polymerase显示文摘Tuerk C Gold L 1990Science1990,249,4968:1
14Comparison of cancer risk estimates based on avariety of risk assessment methodologies 显示文摘GOLD L S GAYLOR D W SLONE T H 2003Regul Toxicol Pharmacol2003,237,:1
15The SELEX process :a surprising source of therapeutic and diagnostic compoundes 显示文摘Gold L 1995Harvey Lect1995,91,:1
16TCR-mediated Notch signaling regulates proliferation and IFN-γ production in peripheral T cells显示文摘Palaga T Miele L Golde TE 2003J Immunol2003,171,6:1
17Musculoskeletal infection of the extremitics: evaluation with MR imaging显示文摘TANG J S H GOLD R H BASSET L W 1998Radiology1998,166,:1
18Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase 显示文摘Tuerk C Gold L 1990Science1990,249,4968:1
19Nitrous oxide generation,denitrification,and nitrate removal in a seepage wetland intercepting surface and subsurface flows from a grazed dairy catchment显示文摘Zaman M M L Nguyen A J Gold P M Groffman D Q Kellogg R J Wilcock 0,,6:1
20Evaluating the Pedi-atric Early Warning Score (PEWS) System for Admitted Pa-tients in the Pediatric Emergency Department显示文摘Gold D L Mihalov L K Cohen D M 2014Acad E-merg Med2014,21,11:1
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