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| 1 | Investigation of hepatoprotective activity of Cyathea gigantea(Wall.ex.Hook.)leaves against paracetamol-induced hepatotoxicity in rats显示文摘Objective:To investigate the hepatoprotective activity of methanolic leaf extract of Cyathea gigantea(C.gigantea)against paracetamol induced liver damage in rats.Methods:The hepatoprotective activity for plant extract was investigated for paracetamol induced hepatoxicity in rats.Wislar albino rats of either sex were divided into five groups of 6 animals each and are given orally the following treatment for seven days.The normal control group was given 1%Na.CMC 1mL/kg bw,p.o.Paracetamol at dose of 1g/kg bw,p.o.was given as toxic dose for inducing hepatoloxicity.Silymarin(50mg/kg.p.o.) was given as reference standard.Two doses of C. gigantea extract i.e.,100 mg/kg.p.o.and 200 mg/kg,p.o.were tested for hepatoprotective activity. The treatment was given for seven days and after 24 h of last treatment blood was collected from retro-orbital plexus and analysed for various serum parameters like serum glutamic-oxaloacetic transaminase(SGOT),serum glutamic pyruvic transaminase(SGPT),alkaline phosphatase(ALP),total bilirubin(TB)and total protein(TP)in different groups.Results:The paracetamol intoxication lead to histological and biochemical deteriorations.The treatment with methanolic leaf extract of C.gigantea reduced the elevated levels of SCOT,SGPT,ALP,TB and also reversed the hepatic damage towards normal which further supports the hepatoprotective activity of leaf extract of C.gigantea.Conclusions:The methanolic extract of leaves of C.gigantea at doses of 100 mg/kg bw and 200 mg/kg bw have significant effect on liver of paracetamol induced hepatotoxicity model in rats. | P Madhu Kiran A Vijaya Raju B Ganga Rao | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，5： | 7 |
| 2 | Aroma improving in microvinification processes by the use of a recombi-nant wine yeast strain expressing the AspergiUus nidulans xlnA gene 显示文摘 | GANGA M A PINAGA F VALLES S | 1999 | International Journal of Food Microbiology1999，47，3： | 1 |
| 3 | Antibody profiles characteristic of Mycobacterium tuberculosis Infection state 显示文摘 | Davidow A Ganga VK Lanbo s hi | 2005 | Infection and Immunity2005，73，10： | 1 |
| 4 | Observation of a topological phase by means of nonplanar Mach-Zehnder interferometer 显示文摘 | Chiao R Y Antaramian A Ganga K M | 1988 | Physical Revew Letters1988，60，13： | 1 |
| 5 | Needle-free, non-adjuvanted skin immunization by electroporation-enhanced transdermal delivery of diphtheria toxoid and a candidate peptide vaccine against hepatitis B virus显示文摘 | Misra A Ganga S Upadhyay P | 2000 | Vaccine2000，18，： | 1 |
| 6 | Detection of the in- fectious hematopoietic necrosis virus directly from infected fish tissues by dot blot hybridization with a non-radioactive probe 显示文摘 | Gonzcilez M P Sdnchez X Ganga M A | 1997 | Journal of Virology Methods1997，65，2： | 1 |
| 7 | Detection of the infectious hematopoietic necrosis virus directly from infected fish tissues by dot blot hybridization with a non-radioactive probe显示文摘 | Gonzilea M P Sinchez X Ganga M A | 1997 | J Virol Methods1997，65，： | 1 |
| 8 | Tensile properties of natural fabric hildegardia pepulifolia/polycarbonate toughened epoxy composites 显示文摘 | VARADA R A BABU R G GANGA D L | 2004 | Polymer Composites2004，25，6： | 1 |
| 9 | Detection of the in- fectious hematopoietic necrosis virus directly from infected fish tissues by dot blot hybridization with a non-radioactive probe 显示文摘 | Gonzdlez M P Sdnchez X Ganga M A | 1997 | Journal of Virology Methods1997，65，2： | 1 |
| 10 | Preparation of feather keratin hydrolyzate-gelatin composites and their graft copolymers显示文摘 | Kavitha A Boopalan Kamala Radhakrishnan Ganga | 2005 | J Macromol Sci Pure Appl Chem2005，42，12： | 1 |
| 11 | Bank Liquidity Risk Management and Supervision: Which Lessons from Recent Market Turmoil? 显示文摘 | Vento G A La Ganga P | 2009 | Journal of Money Investment and Banking2009，2，10： | 1 |
| 12 | Preparation of feather keratin hydrolyzate-gelatin composites and their graft copolymers显示文摘 | Kavitha A Boopalan Kamala Radhakrishnan Ganga | 2005 | J Maeromoleeular Sci Pure Appl Chem2005，42，12： | 1 |
| 13 | Needle-free, non-adjuvanted skin immunization by electroporation-enhanced transdermal delivery of diphtheria toxoid and a candidate peptide vaccine against hepatitis B virus 显示文摘 | Misra A Ganga S Upadhyay P | 2000 | Vaccine2000，18，56： | 1 |
| 14 | A new approach for enchancing Sr^2+ retention by an Al-PILC in acidic solutions 显示文摘 | Papachristodoulou C A Assimakopoulos P A Gangas N H Karamanis D T | 2000 | Micropor Mesopor Mater2000，39，12： | 1 |
| 15 | A new approach for enhancing Sr^2+ retention by an Al PILC in acidic solutions显示文摘 | Papachristodoulou C A Assimakopoulos P A Gangas N H | 2000 | Microporous and Mesoporous Matl2000，39，12： | 1 |
| 16 | Detection of the infectious hematopoietic necrosis virus directly from infected fish tissues by dot blot hybridization with a non-radio- active probe 显示文摘 | Gonzdlea M P Sdnchez X Ganga M A | 1997 | Journal of Virological Methods1997，65，2： | 1 |
| 17 | 显示文摘 | Rodenburg R J Ganga A Van Lent PL | 2000 | Arthritis Rheum2000，43，： | 1 |
| 18 | Polymerase chain reaction confirmatory method for microbiological detection of Brettanomyces bruxellensis in wines显示文摘 | CONTRERAS A SALINAS F GANGA A | 2008 | Journal of Rapid Methods & Automation in Microbiology2008，16，4： | 1 |
| 19 | 查看详情显示文摘 | Puntoriero F La Ganga G Sartorel A Carraro M Scorrano G Bonchio M Campagna S | | 0，，： | 1 |
| 20 | Hydrogenation of benzeneon Ni/Al-pillared saponite catalysts 显示文摘 | Louloudi A Michalopoulos J Gangas N | 2003 | Applied Catalysis A:General2003，，： | 1 |
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