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| 1 | Silent diabetic nephropathy显示文摘AIM: To examine the risk of renal events in patients with biopsy-proven diabetic nephropathy(DN) and its possible associated factors.METHODS: Clinical and histological data of 60 patients diagnosed with diabetic nephropathy were retrospectively collected. Patients with evidence or suspicion of other nephropathies were excluded from the study. The final event was defined as renal replacement therapy(RRT) initiation or progression of chronic kidney disease(CKD), according to the KDIGO 2012 definition of a decrease in CKD category and a decrease in GFR of 25% or more. RESULTS: A total of 45 patients with a follow-up of at least 3 mo were included. Most of the patients presented type 2 DM, with a median age of 58.3 years old. The time of evolution of DM was 9.6 ± 7.8 years, although in 13 patients, it was less than 5 years. A total of 62% of patients reached the final event in a mean period of 3.4 years(95%CI: 2.1-4.7), with 21 of them requiring dialysis. The factors that were independently associated with renal survival were estimated glomerular filtration rate(e GFR) at the time of biopsy, cardiovascular disease(CVD) history and Hb A1 c less than 7%. Therefore, for each 10 m L/min per 1.73 m2 reduction in e GFR, we obtained a DN progression risk of HR = 2(1.3-3.0)(P = 0.001); patients with CVD were at greater risk for DN progression(HR = 2.8, 1.1-7.1, P = 0.032), and CKD patients with Hb A1 c < 7% demonstrated greater renal risk than patients with Hb A1 c ≥ 7%, with an HR of 2.9(1.0-8.4)(P = 0.054).CONCLUSION: A past history of CVD is a risk factor for DN progression. Levels of Hb A1 c less than 7% could favor an e GFR decrease in these patients. | Katia López-Revuelta Patricia Pea Galdo Ramona Stanescu Leticia Parejo Carmen Guerrero Elia Pérez-Fernández | 2014 | World Journal of Nephrology2014，3，1： | 2 |
| 2 | Therapeutic effectiveness of recombinant cancer vaccines is associated with a prevalent T-cell receptor alpha usage by melanoma-specific CD8 + T lymphocytes 显示文摘 | De Palma R Marigo I Del Galdo F | 2004 | Cancer Res2004，64，21： | 1 |
| 3 | Osteoarthritis chondrocytes die by apoptosis a possible pathway for osteoarthritis pathology显示文摘 | Blanco FJ Galdo F Detoro FJ | 1998 | Arthritis Rheum1998，41，2： | 1 |
| 4 | T cells expressing allograft inflammatory factor 1 display increased chemotaxis and induce a profibrotic phenotype in normal fibroblasts in vitro显示文摘 | Del Galdo F Jimenez SA | 2007 | Arthritis Rheum2007，56，10： | 1 |
| 5 | Patients with acute coronary syndrome show oligoclonal T-cell recruitment within unstable plaque:evidence for a local,intracoronary immunologic mechanism显示文摘 | De Palma R Del Galdo F Abbate G | 2006 | Circulation2006，113，5： | 1 |
| 6 | Patients with acute coronary syndrome show oligoclonal T-cell recruitment with in unstable plaque: Evidence for a local, intracoronary immunologic mechanism 显示文摘 | De Palma R Del Galdo F Abbate G | 2006 | Circulation2006，113，5： | 1 |
| 7 | Assessing the impact of land-use change on soil C sequestration in agricultural soils by means of organic matter fractionation and stable C isotopes 显示文摘 | Del Galdo I Six J Peressotti A | 2003 | Global Change Biology2003，9，： | 1 |
| 8 | Quantification of tropical soil attributes from ETM+/LANDSAT-7data显示文摘 | DEMATTE GALDOS GUIMARAES | 2007 | International Journal of Remote Sensing2007，28，1718： | 1 |
| 9 | T cells expressing allograft inflammatory factor I display increased chemotaxis and induce a profibrotic phenotype in normal fibroblasts in vitro 显示文摘 | Del Galdo F Jimenez SA | 2007 | Arthritis Rheum2007，56，10： | 1 |
| 10 | Patients with acute coronary syndrome show oligoclonal T cell recruitment within unstable plaque:evi-dence for a local,intracoronary immunologic mechanism显示文摘 | De Palma R Del Galdo F Abbate G | 2006 | Circulation2006，113，5： | 1 |
| 11 | Trends in global warming and human health impacts related to Brazilian sugarcane ethanol production considering black carbon emissions 显示文摘 | Galdos M Cavalett O Seabra J E A | 2013 | Applied Energy2013，104，： | 1 |
| 12 | Patients with acute coronary syndrome show oligoclonal T-ceU recruitment within unstable plaque: evidence for a local, intracomnary immunologic mechanism 显示文摘 | De Palma R Del Galdo F Abbate G | 2006 | Circulation2006，113，5： | 1 |
| 13 | Patients with acute coronary syndrome show oligoclonal T-cell recruitment within unstable plaque:evidence for a local, intracoronary immunologic mechanism显示文摘 | De Palma R Del Galdo F Abbate G | 2006 | Circulation2006，113，5： | 1 |
| 14 | Assessing the impact of land-use change on soil C sequestration in agricultural soils by means of organic matter fractionation and stable C isotopes显示文摘 | Del Galdo I Six J Peressotti A | 2003 | Global Change Biology2003，9，： | 1 |
| 15 | Methodology for impact factor of horizontally curved box bridge 显示文摘 | Galdos N H Schelling D R Sahin M A | 1993 | Journal of Structural Engineering ASCE1993，119，6： | 1 |
| 16 | Association of a low serum albumin with infection and increased mortality in critically Ill patients显示文摘 | E. Domínguez de Villota J. M. Mosquera J. J. Rubio P. Galdos V. Díez Balda J. L. Serna M. I. Tomás | 1980 | Intensive Care Medicine1980，，1： | 1 |
| 17 | Assessing the impact of land-use change on soil C sequestration in agricultural soils by means of organic matter fractionafion and stable C isotopes 显示文摘 | De1 Galdo I Six J Peressotti A | 2003 | Glob Change Biol2003，9，： | 1 |
| 18 | Assessing the impact of land use change on soil C sequestration in agricultural soils by means of organic matter fractionation and stable C isotopes 显示文摘 | Galdo D Six J Peressotti A | 2003 | Global Change Biology2003，9，： | 1 |
| 19 | Sputum Induction in Children: Technical Developmen显示文摘 | Vizmanos Lamotte G Moreno Galdo A Cruz Carmona M J | 2010 | An Pediatr (Bare)2010，72，3： | 1 |
| 20 | Patients with acute coronarysyndrome show oligoclonal T-cell recruitment within unstable plaque: evidence for a local, intracoronary immunologic mechanism 显示文摘 | de Palma R Del Galdo F Abbate G | 2006 | Circulation2006，113，5： | 1 |
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