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| 1 | Rectal cancer: An evidence-based update for primary care providers显示文摘Rectal adenocarcinoma is an important cause of cancer-related deaths worldwide, and key anatomic differences between the rectum and the colon have significant implications for management of rectal cancer. Many advances have been made in the diagnosis and management of rectal cancer. These include clinical staging with imaging studies such as endorectal ultrasound and pelvic magnetic resonance imaging, operative approaches such as transanal endoscopic microsurgery and laparoscopic and robotic assisted proctectomy, as well as refined neoadjuvant and adjuvant therapies. For stage Ⅱ and Ⅲ rectal cancers, combined chemoradiotherapy offers the lowest rates of local and distant relapse, and is delivered neoadjuvantly to improve tolerability and optimize surgical outcomes, particularly when sphincter-sparing surgery is an endpoint. The goal in rectal cancer treatment is to optimize diseasefree and overall survival while minimizing the risk of local recurrence and toxicity from both radiation and systemic therapy. Optimal patient outcomes depend on multidisciplinary involvement for tailored therapy. The successful management of rectal cancer requires a multidisciplinary approach, with the involvement of enterostomal nurses, gastroenterologists, medical and radiation oncologists, radiologists, pathologists and surgeons. The identification of patients who are candidates for combined modality treatment is particularly useful to optimize outcomes. This article provides an overview of the diagnosis, staging and multimodal therapy of patients with rectal cancer for primary care providers. | Wolfgang B Gaertner Mary R Kwaan Robert D Madoff Genevieve B Melton | 2015 | World Journal of Gastroenterology2015，21，25： | 13 |
| 2 | Multidisciplinary and evidence-based management of fistulizing perianal Crohn's disease显示文摘Perianal symptoms are common in patients with Crohn's disease and cause considerable morbidity. The etiology of these symptoms include skin tags, ulcers, fissures, abscesses, fistulas or stenoses. Fistula is the most common perianal manifestation. Multiple treatment options exist although very few are evidence-based. The phases of treatment include: drainage of infection, assessment of Crohn's disease status and fistula tracts, medical therapy, and selective operative management. The impact of biological therapy on perianal Crohn's disease is uncertain given that outcomes are conflicting. Operative treatment to eradicate the fistula tract can be attempted once infection has resolved and Crohn's disease activity is controlled. The operative approach should be tailored according to the anatomy of the fistula tract. Definitive treatment is challenging with medical and operative treatment rarely leading to true healing with frequent complications and recurrence. Treatment success must be weighed against the risk of complications, specially anal sphincter injury. A full understanding of the etiology and all potential therapeutic options is critical for success. Multidisciplinary management of fistulizing perianal Crohn's disease is crucial toimprove outcomes. | Ricardo Sordo-Mejia Wolfgang B Gaertner | 2014 | World Journal of Gastrointestinal Pathophysiology2014，5，3： | 5 |
| 3 | Iron catalyzed Michael addition: Chloroferrate ionic liquids as efficient catalysts under microwave conditions显示文摘The iron containing ionic liquid 1-butyl-3-methylimidazolium tetrachloroferrate ([C4mim]Cl/FeCl3; = 0.5) proved to be an efficient catalyst for the solvent-free metal catalyzed Michael addition of β-keto esters and enones. Due to the ionic structure of the catalyst, a significant acceleration of the reaction rate was observed under microwave conditions. Furthermore, recycling of the ionic liquid catalyst could be performed after simply distilling off the products. | VASILOIU Maria GAERTNER Peter BICA Katharina | 2012 | Science China Chemistry2012，55，8： | 2 |
| 4 | 汽车14V电气能量管理系统及其应用显示文摘针对传统的车辆电气系统中,发电机的输出电压与蓄电池的状态难以监测和部分电负载不可控制的问题,本文中对14V电气能量管理(14V-EEM)系统进行研究。该系统可在发动机和蓄电池的有利工作状态下,适时主动地调节发电机的输出电压和控制部分与安全无关的大功率电负载,在满足整车电气能量需求的同时,提高了整车燃油经济性和整车电气网络可靠性。最后以一汽红旗H7某款车型作为14V-EEM系统运行载体,进行了NEDC工况下的测试。结果表明,油耗约降低2%,蓄电池的电平衡为正值,达到了预期效果。 | 纪光霁 韩玉涛 王晶淼 Gaertner Christian | 2016 | 汽车工程2016，38，4： | 2 |
| 5 | The Evolving Role of Laparoscopy in Colonic Diverticular Disease: A Systematic Review显示文摘 | Wolfgang B. Gaertner Mary R. Kwaan Robert D. Madoff David Willis George E. Belzer David A. Rothenberger Genevieve B. Melton | 2013 | World Journal of Surgery2013，，3： | 2 |
| 6 | Structural Determinants of Job Satisfaction and Organizational Commitment in Turnover Models 显示文摘 | Gaertner S | 1999 | Human Resource Management Review1999，9，4： | 1 |
| 7 | A meta - analysis ofantecedents and correlates of employee turnover: Update, moderatortests,and research implications for the millennium 显示文摘 | GRIFFETH R W HOM P W GAERTNER S | 2000 | Journal ofManagement2000，26，3： | 1 |
| 8 | Amended recombina- nt cells (ARCs) expressing bovine IFN-gamma: an economical and highly effective adjuvant system 显示文摘 | Gaertner FH Babiuk LA Mutwiri G et ol | 2009 | Vaccine2009，27，9： | 1 |
| 9 | Perspec- tives on curriculum needs in laboratory-animal medi- cine显示文摘 | Turner PV Colby LA Gaertner DJ | 2009 | Journal of Veterinary Medical Education2009，36，1： | 1 |
| 10 | Applications of chiral ionic liquids显示文摘 | Bica K Gaertner P | 2008 | Eur J Org Chem2008，19，： | 1 |
| 11 | Advances in pharmacotherapy for opioid-induced constipation-a systematic review显示文摘 | Siemens W Gaertner J Becker G | 2015 | Expert Opin Pharmacother2015，16，4： | 1 |
| 12 | Risk of bladder cancer in foundry workers:a meta-analysis显示文摘 | Gaertner RRW Thériault GP | 2002 | Occup Environ Med2002，59，10： | 1 |
| 13 | Load-related bonemodelling at the interface of orthodontic micro-implants显示文摘 | Büchter A Wiechmann D Gaertner C | 2006 | ClinOral Implants Res2006，17，6： | 1 |
| 14 | Visceral adhesions to hernia prostheses显示文摘 | Gaertner WB Bonsack ME Delaney JP | 2010 | Hernia2010，14，4： | 1 |
| 15 | Site-specific attachment of functionalized poly(ethylene glycol) to the amino terminus of proteins显示文摘 | Gaertner HF Offord RE | 1996 | Biocongucate Chem1996，7，： | 1 |
| 16 | A meta-analysis of antecedents and correlates of emplotee turnover: update, moderator test, and research implications for the next millennium显示文摘 | Griffeth R W Hom P W Gaertner S | 2000 | Journal of Management2000，26，： | 1 |
| 17 | A Meta-analysis of Antecedents and Correlates of Employee Turnover : Update, Modera- tor Tests, and Research Implications for the Next Millennium显示文摘 | Griffeth R W Hom P W Gaertner S | 2000 | Journal of management2000，26，3： | 1 |
| 18 | Development of a generalized parameter window for cold spray deposifion显示文摘 | Schmidt T Gaertner F Assadi H | 2006 | Acta Materialia2006，54，： | 1 |
| 19 | Inter- group threat and outgroup attitudes: a meta-analytic review显示文摘 | RIEK BM MANIA EW GAERTNER SL | 2006 | Pets Soc Psychol Rev2006，10，4： | 1 |
| 20 | Structural determinants of job satisfaction and organizational commitment in turnover models显示文摘 | Gaertner S | 1999 | Human Resource Management Review1999，9，： | 1 |
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