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| 1 | Spleen-preserving distal pancreatectomy with conservation of the splenic artery and vein显示文摘Preservation of the spleen at distal pancreatectomy has recently attracted considerable attention.Since our first successful trial,spleen-preserving distal pancreatectomy with conservation of the splenic artery and vein for tumors of the pancreas and chronic pancreatitis has been performed more frequently.The technique for spleen-preserving distal pancreatectomy with conservation of the splenic artery and vein are outlined.The splenic vein is identified behind the pancreas and within the thin connective tissue membrane.The connective tissue membrane is cut longitudinally above the splenic vein.An important issue is to remove the splenic vein from the body of the pancreas toward the spleen,since a different approach may be very difficult.The pancreas is preferably removed from the splenic artery toward the head of the pancreas itself.This procedure is much easier than removing the pancreas from the vein side.One patient had undergone distal gastrectomy for duodenal ulcer,with reconstruction by Billroth Ⅱ tehcnique.If distal pancreatectomy with splenectomy had been performed for the lesion of the distal pancreas at the time,the residual stomach would also have to be resected.The potential damage done to the patient by reconstruction of the gastrointestinal tract in combination with distal pancreatectomy and splenectomy would have been much greater than with distal pancreatectomy only with preservation of the spleen and residual stomach.Benign lesions as well as low-grade malignancy of the body and tail of the pancreas may be a possible indication for this procedure. | Wataru Kimura Toshiyuki Moriya Jinfeng Ma Yukinori Kamio Toshihiro Watanabe Mitsukiro Yano Hiroto Fujimoto Koji Tezuka Ichiro Hirai Akira Fuse | 2007 | World Journal of Gastroenterology2007，13，10： | 24 |
| 2 | Pancreatic schwannoma:Case report and an updated 30-year review of the literature yielding 47 cases显示文摘Pancreatic schwannomas are rare neoplasms.Authors briefly describe a 64-year-old female patient with cystic pancreatic schwannoma mimicking other cystic tumors and review the literature.Databases for PubMed were searched for English-language articles from 1980 to 2010 using a list of keywords,as well as references from review articles.Only 41 articles,including 47 cases,have been reported in the English literature.The mean age was 55.7 years(range 20-87 years),with 45%of patients being male.Mean tumor size was 6.2 cm(range 1-20 cm).Tumor location was the head(40%),head and body(6%),body(21%),body and tail(15%),tail(4%),and uncinate process(13%).Thirty-four percent of patients exhibited solid tumors and 60%of patients exhibited cystic tumors.Treatment included pancreati-coduodenectomy(32%),distal pancreatectomy(21%),enucleation(15%),unresectable(4%),refused opera-tion(2%)and the detail of resection was not specified in 26%of patients.No patients died of disease with a mean follow-up of 15.7 mo(range 3-65 mo),although 5(11%)patients had a malignancy.The tumor size was significantly related to malignant tumor(13.8±6.2 cm for malignancy vs 5.5±4.4 cm for benign,P=0.001) and cystic formation(7.9±5.9 cm for cystic tumorvs 3.9 ±2.4 cm for solid tumor,P=0.005).The preoperative diagnosis of pancreatic schwannoma remains difficult.Cystic pancreatic schwannomas should be considered in the differential diagnosis of cystic neoplasms and pseudocysts.In our case,intraoperative frozen section confirmed the diagnosis of a schwannoma.Simple enucleation may be adequate,if this is possible. | Toshiyuki Moriya Wataru Kimura Ichiro Hirai Akiko Takeshita Koji Tezuka Toshihiro Watanabe Masaomi Mizutani Akira Fuse | 2012 | World Journal of Gastroenterology2012，18，13： | 8 |
| 3 | Toll-like receptor 9 gene mutations and polymorphisms in Japanese ulcerative colitis patients显示文摘Abnormal innate immune responses toward luminal bacteria play an important role in the pathogenesis of inflammatory bowel disease.It has been demonstrated that bacteria having CpG DNA ameliorate experimental colitis in mice,and Toll-like receptor 9 (TLR9) signaling mediates the anti-inflammatory effects in mouse colonic inflammation.A gene variation in NOD2/CARD15 has been reported in Crohn's disease (CD) patients in Western countries,but this variation has not been identified in Japanese CD patients.Therefore,we hypothesized that TLR9 is a key factor in the development of ulcerative colitis (UC),and we investigated gene mutations and polymorphisms of TLR9 in Japanese UC patients.Three single nucleotide polymorphisms (SNPs) in TLR9 were identified in healthy controls,and were assessed in 48 UC patients and 47 healthy controls.Control subjects were matched for age,sex and date of blood sampling from among a subgroup of participants.We found that TLR9-1486CC,1174GG and 2848AA increase the risk of UC [odds ratio (OR) 2.64,95% confidence interval (95% CI):1.73-6.53,P=0.042],and TLR9-1486TT,1174AA and 2848GG decrease the risk of UC (OR 0.30,95% CI:0.10-0.94,P=0.039),although there were no correlations between SNPs and disease phenotype or TLR9 mRNA expression.These findings suggest that TLR9 polymorphisms are associated with increased susceptibility to UC. | Kaori Fuse Kyoko Katakura Natsumi Sakamoto Hiromasa Ohira | 2010 | World Journal of Gastroenterology2010，16，46： | 4 |
| 4 | Cardiac output and circulating blood volume analysis by pulse dye-densitometry显示文摘 | Takehiko Iijima Takuo Aoyagi Yasuhide Iwao Junichi Masuda Masayoshi Fuse Naoki Kobayashi Hiroshi Sankawa | 1997 | Journal of Clinical Monitoring1997，，2： | 2 |
| 5 | Proposal of a Multi-core Model for Polymer Nanocomposite Dielectrics显示文摘 | Tanaka T Kozako M Fuse N | 2005 | IEEE Transactions on Dielectrics and Electrical Insulation2005，12，4： | 1 |
| 6 | N-terminal pro-brain natriuretic Peptide as a useful diagnostic marker of acute Kawasaki disease in children 显示文摘 | Shiraishi M Fuse S Mori T | 2013 | Circ J2013，77，8： | 1 |
| 7 | Proposal of a mul- ti-core model for polymer nanocomposite dielectrics显示文摘 | TANAKA T KOZAKO M FUSE N | 2005 | IEEE Transactions on Dielectrics and Electrical Insula- tion2005，12，4： | 1 |
| 8 | Clinical significance of vascular endothelial growth factor in patients with primary lung cancer 显示文摘 | Kishirol Kato S Fuse D | 2002 | Respirology2002，7，2： | 1 |
| 9 | Thrombopoietin activates the growth of megakeryoblasts in patients with chronic myeloproliferative diseases and myelodysplastic syndrome显示文摘 | Hesimoto S Toba K Fuse I | 2000 | EurJ Hematol2000，64，： | 1 |
| 10 | The effects of cyclosporin azathioprine and mizoribine on male reproduction in rats显示文摘 | Iwasaki M Fuse H Katayama T | 1996 | Nippon Hinyokika Gakkai Zasshi1996，87，1： | 1 |
| 11 | Magnetic resonance imaging to diagnose segmental testicular infarction显示文摘 | Kodama K Yotsuyanagi S Fuse H | 2000 | J Urol2000，163，3： | 1 |
| 12 | 显示文摘 | Miyagi T Fuse H Takashima M | 2001 | Hinyokika Kiyo2001，47，6： | 1 |
| 13 | Proposal of a multi-core model for polymer nanocomposite dielectrics显示文摘 | Tanaka T Kozako M Fuse N | 2005 | IEEE Transactions on Di- electrics and Electrical Insulation2005，12，4： | 1 |
| 14 | Hematospermia: etiolo- gy, diagnosis, and treatment显示文摘 | Hideki Fuse Akira Komiya Tetsuo Nozaki | 2011 | Reprod Med Biol2011，10，3： | 1 |
| 15 | Successful cochlear implantation in prelingual profound deafness resulting from the common 233delC mutation of the GJB2 gene in the Japanese显示文摘 | Matsushiro N Doi K fuse Y | 2002 | Laryngoscope2002，112，2： | 1 |
| 16 | Short - term prognostic value of initial serum levels of interleukin - 10 in patients with acute myocarditis 显示文摘 | Fuse K Kodama M Okura Y | 2005 | Ettr J Heart Fail2005，，： | 1 |
| 17 | The contemporary European zinc cycle:1-year stocks and flows显示文摘 | Spatari S Bertram M Fuse K | 2003 | Resources Conservation & Recycling2003，39，： | 1 |
| 18 | Surgical management for metastat- ic liver tumors显示文摘 | Hirai I Kimura W Fuse A | 2006 | Hepatogastroenterology2006，53，71： | 1 |
| 19 | Enhanced expression and production of monocyte chemoattractant protein-1 in myocardifis显示文摘 | Fuse K Kodama M Hanawa H | | 0，，03： | 1 |
| 20 | Osmoregulation in the parasitic nematode Pseudoterranova decipiens显示文摘 | FUSE M DAVEY K SOMMERVILLE R | 1993 | Journal of Experimental Biology1993，175，1： | 1 |
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