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| 1 | Single grain Rb-Sr dating of euhedral and cataclastic pyrite from the Qiyugou gold deposit in western Henan, central China显示文摘The Rb-Sr isotopic dating of pyrite mineral from ore deposits can directly provide mineralization age. However, many geological factors may affect the Rb-Sr isotopic system,which baffles application of this method. Employing ultra-low procedural blank Rb-Sr method,we have dated pyrites separated from the No. 4 breccia pipe of the Qiyugou gold deposit,western Henan Province. Single grains of euhedral pyrite crystal with few microcracks yield an isochron age of 126 ± 11 Ma, which represents time of the main mineralization stage of the deposit. Pyrite grains of cataclastic type show nevertheless scattered Rb-Sr isotopic composition and no reasonable isochron can be defined. Crystal morphology and mineral inclusion studies reveal that Rb and Sr of pyrite mineral probably are preserved mainly in biotite, K-feldspar, and sericite mineral inclusions. The dating results likely suggest that cataclastic pyrite is not suitable for the Rb-Sr dating due to modification of the Rb-Sr isotopic system by later hydrothermal activity of fluid. | HAN YiGui LI XiangHui ZHANG ShiHong ZHANG YuanHou CHEN FuKun | 2007 | Chinese Science Bulletin2007，52，13： | 27 |
| 2 | Numerical simulation of the influences of sinker weight on the deformation and load of net of gravity sea cage in uniform flow显示文摘A numerical model for determining fishing net configuration and load is developed, based on the lumped masses method. The model is used to analyze the influences on the net of gravity sea cage by different sinker weights in uniform flow. The net of gravity sea cage is simulated under different current velocities and sinker weights. In order to verify the validity of the numerical results, model test results made by Lader and Enerhaug are cited and compared with the numerical ones. The results of numerical simulation agree well with the experimental ones and the agreement is within an error range of 13% under different velocities and sinker weights. The numerical results indicate that increasing the sinker weight can effectively reduce the net deformation, but the total drag force on the net will increase accordingly. Results will give references for better knowledge of the hydrodynamic behavior of gravity sea cage. | LI Yucheng ZHAO Yunpeng GUI Fukun TENG Bin DONG Guohai | 2006 | Acta Oceanologica Sinica2006，25，3： | 16 |
| 3 | Ultra-low procedural blank and the single-grain mica Rb-Sr isochron dating显示文摘Both low procedural blank and high-precision measurements of isotopic ratios are crucial for the analysis of micro samples. This study reports a chemical procedure of ultra-low blank for the high precision measurement of Sr isotopic ratios on micro samples (<1 ng level) using a new-type thermal ionization mass spectrometer IsoProbe-T, with a case study of single-grain Rb-Sr isochron dating on phlogopite from the Fuxian kimberlite in Liaoning Province. This method can be employed in studies of high resolution Rb-Sr geochronology and Sr isotopic geochemistry and thus will broaden application of the Rb-Sr isotopic system to earth sciences. | LI Qiuli HEN Fukun WANG Xiuli LI Xianghui LI Chaofeng | 2005 | Chinese Science Bulletin2005，50，24： | 15 |
| 4 | Elevated expression of mature miR-21 and miR-155 in cancerous gastric tissues from Chinese patients with gastric cancer显示文摘Objective:MicroRNA (miRNA) expression is deregulated in many types of human cancers.We sought to investigate the expression patterns of the miRNAs,miR-21,miR-145 and miR-155 in sporadic gastric cancer in a Chinese population.Methods:Total RNA was extracted from archived gastric cancer tissues and adjacent non-cancerous tissues from 20 pairs of paraffin-embedded specimens.Expression levels of miR-21,miR- 145 and miR-155 were detected by quantitative reverse transcriptase PCR using a specific stem-loop primer,with U6 as the internal reference gene.Results:The expression of miR-21 and miR-155 in gastric cancer samples was significantly higher than in paired non-cancerous samples(P<0.05).There was no statistically significant difference in expression levels of miR-145 between cancerous and non-cancerous tissues(P>0.05).Conclusion:In Chinese sporadic gastric cancer tissues,the expressions of the oncogenic miR-21 and miR-155 were significantly up-regulated,while the expression of the tumor suppressor miR-145 was decreased,although this decrease was not statistically significant.Thus there is specificity in the miRNA expression pattern in gastric cancers in the Chinese population. | Li Liu Qi Chen Rensheng Lai Xiaobin Wu Xiaoyu Wu Fukun Liu Guohua Xu Yong Ji | 2010 | The Journal of Biomedical Research2010，24，3： | 11 |
| 5 | Determination on ^(87)Sr/^(86)Sr ratio and stratigraphic dating of single-grain foraminifera显示文摘The Sr isotopic composition of foraminifera has been used in studies of chronstratigraphy and sedi- mentary geochemistry. However, it is difficult to sample foraminifera without overprinting of later diagenesis, which contains enough amount of Sr for isotopic measurement. Analysis of single-grain foraminifera was successively conducted by a combination of low Sr procedural blank and high precision determination of 87Sr/86Sr ratio. This combi- nation of single-grain foraminifera can be significant for the study and application of Sr isotopic composition of fo- raminifera. Measured foraminifera of this study, having a size between 250 μm and 400 μm, were sampled from the carbonate basement of a ferromanganese crust in western Pacific. Mean value of 87Sr/86Sr ratios of the analyzed sin- gle-grain foraminifera is 0.709150 ±0.000013 with internal precision between 4 ppm and 8 ppm for each measurement run. Average value of total procedural blank of Sr is 14 pg. It is significant but difficult to date foraminifera in carbonate basements of ferromanganese crusts. Based on the ob- tained value of 87Sr/86Sr ratio, the analyzed foraminifera can be dated at 0.91 +0.33/?0.39 Ma. | TONG Jinggui LI Shengrong LI Xiannhui LI Qiuli FANG Nianqiao CHU Fengyou CHEN Fukun | 2006 | Chinese Science Bulletin2006，51，17： | 6 |
| 6 | Expression and characterization of two secreted His6-tagged endo-β-1,4- glucanases from the mollusc Ampullaria crossean in Pichia pastoris显示文摘 | Rui Guo Ming Ding Siliang Zhang Genjun Xu Fukun Zhao | 2008 | Acta Biochimica et Biophysica Sinica2008，40，5： | 5 |
| 7 | A Harmful-Intrusion Detection Method Based on Background Reconstruction and Two-Dimensional K-S Test in an Optical Fiber Pre-Warning System显示文摘为光纤维侵入警告前系统(OFIPS ) 的关键技术和主要困难是有害侵入的信号的抽取。在被阶段敏感的光时间域反射计处理以后(-OTDR), 颤动信号能 preliminarily 被提取。通常,这些包括噪音和侵入。这里,侵入能被划分成有害、无害的侵入。关于信号特征的仔细的学习,有害侵入的一个有效抽取方法在纸被建议。在背景重建的部分,第一,所有侵入信号被经常的虚惊率(CFAR ) 首先检测。我们然后重建由提取警报点,时间和振幅的由二部合成的信息的背景。这保证察觉背景由侵入信号组成。在二维的 Kolmogorov-Smirnov (K-S ) 测试的部分,第二提取了侵入以便从所有提取有害的,我们设计一个分离方法。它基于有害侵入的信号特征,它是更短的时间间隔和更高的振幅。在实际 OFIPS,察觉方法在一些典型场面被使用,它包括很多无害的侵入,例如构造地点和忙道路。结果证明我们能有效地提取有害侵入。 | Fukun BI Tong ZHENG Hongquan QU Liping PANG | 2016 | Photonic Sensors2016，6，2： | 5 |
| 8 | A coarse-to-fine image registration method based on visual attention model显示文摘Image registration is fundamental and crucial to remote sensing.However getting highly accurate registration performance automatically and fast for large-field images consistently is a challenge.As a work around to this problem,we propose a new image registration concept based on visual attention in this paper.This concept employs the advantages of feature-based or area-based methods to improve the precision and efficiency of image registration.The key concept of proposed integrated scheme is to make optimum use of the highly prominent details in the full scene by means of visual attention computational mechanism.To testify the validation,comparisons with other classical methods are carried out on real-world images.The experimental results show that the proposed method can effectively perform on multi-view/multi-temporal remote sensing images with outstanding precision and time saving performance. | FENG Jing MA Long BI FuKun ZHANG XueJing CHEN He | 2014 | Science China(Information Sciences)2014，57，12： | 5 |
| 9 | Recent updates on cancer immunotherapy显示文摘Traditional cancer therapies include surgery,radiation,and chemotherapy,all of which are typically nonspecific approaches.Cancer immunotherapy is a type of cancer treatment that helps the immune system fight cancer.Cancer immunotherapy represents a standing example of precision medicine:immune checkpoint inhibitors precisely target the checkpoints;tumor infiltrating lymphocytes,TCR T cells,and CAR T cells precisely kill cancer cells through tumor antigen recognition;and cancer vaccines are made from patient-derived dendritic cells,tumor cell DNA,or RNA,or oncolytic viruses,thus offering a type of personalized medicine.This review will highlight up-to-date advancement in most,if not all,of the immunotherapy strategies. | Ming Liu Fukun Guo | 2018 | Precision Clinical Medicine2018，1，2： | 5 |
| 10 | Reservoir space of the Es_3~3–Es_4~1shale in Dongying sag显示文摘The Es33–Es41shales in Dongying sag are source rocks with large reserves of shale oil and gas. For the identification of development characteristics and geological significance of the reservoir space, FMI logging,core observation, thin section analysis, X-ray diffraction, fluorescence microscopy, scanning electron microscopy, mercury porosimetry, low-temperature nitrogen adsorption, atomic force microscopy, and conventional physical property testing were used to study the petrology and reservoir space of the Es33–Es41shale in Dongying sag. The results suggest that the shale is rich in carbonate minerals. Phanerocrystalline stratiform and lamellar argillaceous limestone and calcareous claystone are the oil- and gas-bearing lithofacies. The oil in the micropores is mainly present as membranes and clots. The shale reservoir space has a network structure with veins, carbonate and clay minerals, and micropores among pyrite and the matrix. The results provide the geological framework for future shale oil and gas exploration in Dongying sag. | Hao Yunqing Chen Fukun Zhu Jingquan Zhang Shoupeng | 2014 | International Journal of Mining Science and Technology2014，24，4： | 4 |
| 11 | Detection of oil spills in a complex scene of SAR imagery显示文摘We present a method for detecting oil spills in a complex scene of SAR imagery,including segmenting oil spills,and avoiding false alarms.Segmentation is carried out using a multi-time and multi-hierarchical method by dividing the complex sea surface into bright sea and dark sea.Gray-based and edge-based segmentations are done to extract oil spills from bright and dark sea,respectively.The proposed method can extract complete oil spills,obtain better visual results,and increase detection probability more accurately than the traditional method.Based on the surrounding features and the oil spills’features,dark land spots and low contrast dark spots are removed efficiently,thus reducing false alarms.The experimental results demonstrate that the proposed algorithm has fast computation speed,high detection accuracy,and is very useful and effective for detecting oil spills in SAR imagery. | FENG Jing CHEN He BI FuKun LI JunXia WEI Hang | 2014 | Science China(Technological Sciences)2014，57，11： | 4 |
| 12 | Tracing the sources of particles in the East Rongbuk ice core from Mt. Qomolangma显示文摘Sr-Nd-Pb isotopic tracer was applied, for the first time, to identifying the sources of the particles in the East Rongbuk ice core from Mt. Qomalangma (Everest). The results show that the particles in the dirty layers originate mainly from local sources, while the particles in the non-dirty layers are consistent with the features of dust from the arid regions in northwestern India. The HYSPLIT model shows that the air trajectory goes first through northwestern India before reaching the drilling site of ice core when dust storms occur in northwestern India, confirming northwestern India as a possible source of dust in the East Rongbuk ice core. | XU JianZhong HOU ShuGui CHEN FuKun REN JiaWen QIN DaHe | 2009 | Chinese Science Bulletin2009，54，10： | 4 |
| 13 | Harmful Intrusion Detection Algorithm of Optical Fiber Pre-Warning System Based on Correlation of Orthogonal Polarization Signals显示文摘目前,预付测量基于的光纤维侵入的研究经常的虚惊率(CFAR ) 算法。尽管这些常规方法克服非静止的随机的信号的干扰,仍然在实际应用程序有很多虚惊。这是因为虚惊和侵入的直角的极化信号上没有特定的学习。为了推进,减少虚惊,我们用单个模式的纤维的 birefringence 分析光纤维信号的关联。这篇论文基于二个直角的极化信号的关联建议有害侵入察觉算法。区分虚惊和侵入的建议方法使用关联系数,它能减少虚惊。真实数据的实验,从实际环境镇定,证明在关联的差别是一个柔韧的特征。而且,结果证明建议算法能减少虚惊并且当它在光纤维警告前系统(OFPS ) 被使用时,保证察觉表演。 | Fukun BI Chong FENG Hongquan QU Tong ZHENG Chonglei WANG | 2017 | Photonic Sensors2017，7，3： | 4 |
| 14 | A Novel Algorithm of Water Region Detection in SAR Image Based on Bag of Visual Words and Local Pattern Histogram显示文摘Water region detection based on SAR images is a difficult problem for its computing complexity.This paper proposes a novel water region detection method in SAR image of complex scenery. The algorithm takes advantages of Bag of visual words(BOV) to precisely describe the homogeneous region in complex scenery. Local pattern histogram(LPH) and single-class Support vector machine(SVM) are adopted to determine the edge information of water region precisely. The feature extraction is calculated block by block, which reduces computing workload and interference from noise. The experiments based on SAR images of real complex scenery show that the proposed method achieves higher accuracy and robustness. | FENG Jing CHEN Liang WEI Hang BI Fukun CHEN He | 2016 | Chinese Journal of Electronics2016，25，5： | 3 |
| 15 | Identification, expression, and characterization of the highly conserved D-xylose isomerase in animals显示文摘d 木糖是为动物的必要的糖。从一个软体动物的 xylanase, Ampullaria crossean,被我们的实验室以前报导。这 xylanase 能降级木聚糖进 d 木糖。但是仍然在我们它的新陈代谢的小径上的知识有差距。问题是木糖怎么进入戊糖小径吗?在 genomic 数据库和生物信息的工具的帮助下,我们发现一些动物例如细菌,有高度保存的 d 木糖 isomerase (EC 5.3.1.5 ) 。从海喷射的木糖 isomerase, Ciona intestinalis,不同类地在 Escherichia coli 被表示并且净化了证实它的功能。recombinant 酶面对 Mg2+ 有好热稳定性。在最佳温度和最佳 pH 环境,它 d 木糖上的特定的活动是 0.331 mol/mg/min。这酶在许多广泛地存在动物,而是它消失在像两栖纲的 Xenopus laevis 的染色体。它的顺序高度被保存。从动物的木糖 isomerases 是为进化的学习的很有趣的蛋白质。 | Ming Ding Yigang Teng Qiuyu Yin Wei Chen Fukun Zhao | 2009 | Acta Biochimica et Biophysica Sinica2009，41，2： | 3 |
| 16 | Purification and characterization of a novel endo-β-1,4-glucanase, AfEG22, from the giant snail, Achatina fulica frussac显示文摘在这研究,我们证实了那至少三 endo -- 1,4-glucanases 在巨大的蜗牛的消化果汁存在, Achatina fulica ferussac,由刚果红染色试金。这些酶之一,新奇 endo -- 1,4-glucanase (AfEG22 ) ,是由胶化过滤,阴离子交换,和恐水病的相互作用层析的净化的 29.5 褶层。净化的酶的 carboxymethyl 纤维素(CMC ) hydrolytic 活动是 12.3 U/mg 蛋白质。AfEG22 的分子的团是 MALDI-TOF 决定的 22081 Da。N 终端氨基酸定序揭示了 EQRCTNQGGILKYYNT 的一个序列,它没在强风数据库与任何蛋白质有重要相同。为向 CMC 的 hydrolytic 活动的最佳的 pH 和温度是 pH 4.0 和 | Yigang Teng Qiuyu Yin Ming ding Fukun Zhao | 2010 | Acta Biochimica et Biophysica Sinica2010，42，10： | 3 |
| 17 | Acoustic emission characteristics and stress release rate of coal samples in different dynamic destruction time显示文摘Considering the importance of the prediction of rock burst disasters, and in order to grasp the law of acoustic emission(AE) of coal samples in different dynamic destruction time, the SH-II AE monitoring system was adopted to monitor the failure process of coal samples. The study of the change rule of the AE numbers, energy, ‘b' value and spectrum in the micro crack propagation process of the coal samples shows that as dynamic damage time went by, AE presented high-energy counts and the accumulated counts increased during the compression phase. The AE energy and cumulative counts increased during the elastic stage. The AE blank area increased gradually and the blank lines were more and more obvious in the molding stage. The AE counts and energy showed a trend of decrease in the residual damage phase.AE ‘b' values gradually became sparse, and the large scale cracks percentage compared with micro cracks decreased and the degree of damage decreased. The AE frequency spectrum peak went from the residual damage phase to the molding phase, and finally it was nearly stable, besides the bandwidth of the main frequency is gradually narrowed. Also, the frequency peak changed from single peak frequency to bi-peak frequency and to the single peak frequency. Uniaxial compressive strength is more sensitive than the elastic modulus to dynamic damage time. | Xiao Fukun Liu Gang Zhang Ze Shen Zhiliang Zhang Fengrui Wang Yifei | 2016 | International Journal of Mining Science and Technology2016，26，6： | 3 |
| 18 | A Two-Level Detection Algorithm for Optical Fiber Vibration显示文摘光纤维颤动被协调光时间领域思考技术检测。除了颤动信号,反映的信号包括喧嚷和噪音,它导致高虚惊率。平均经常的虚惊率算法的房间有高计算速度,而是它的察觉表演将在象多重目标那样的 nonhomogeneous 环境被拒绝。顺序统计常数虚惊率算法在多重目标环境有一个明显的优点,但是它有更低的计算速度。一个聪明的二水平的察觉算法基于平均以连续方法,和平均经常的虚惊率和统计常数虚惊率分别地被保存的顺序的性能的房间的察觉速度工作的经常的虚惊率和目统计常数虚惊率的房间被介绍。通过适应选择,平均的房间在同类的环境被使用,并且二水平的察觉算法在 nonhomogeneous 环境被采用。我们的蒙特卡罗模拟结果证明就不同信号噪音比率而言,建议算法比顺序统计的给更好的察觉概率。 | Fukun BI Xuecong REN Hongquan QU Ruiqing JIANG | 2015 | Photonic Sensors2015，5，3： | 2 |
| 19 | The existence and multiplicity of solutions of a fractional Schrdinger-Poisson system with critical growth显示文摘In this paper, we study the existence and multiplicity of solutions for the following fractional Schr¨odinger-Poisson system:ε^(2s)(-?)~su + V(x)u + ?u = |u|~2_s~*-2 u + f(u) in R^3,ε^(2s)(-?)~s? = u^2 in R^3,(0.1)where 3/4< s < 1, 2_s~*:=6/(3-2s)is the fractional critical exponent for 3-dimension, the potential V : R^3→ R is continuous and has global minima, and f is continuous and supercubic but subcritical at infinity. We prove the existence and multiplicity of solutions for System(0.1) via variational methods. | Yuanyang Yu Fukun Zhao Leiga Zhao | 2018 | Science China Mathematics2018，61，6： | 2 |
| 20 | Trace elementand strontium isotope constraints on sedimentary environmentof Ediacaran carbonates in southern Anhui, South China 显示文摘 | Zhao Yanyan Zheng Yongfei Chen Fukun | 2009 | Chem Geol2009，265，34： | 1 |
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