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| 1 | Fibroadhesive scarring of grafted collagen scaffolds interferes with implant–host neural tissue integration and bridging in experimental spinal cord injury显示文摘Severe traumatic spinal cord injury(SCI)results in a devastating and permanent loss of function,and is currently an incurable condition.It is generally accepted that future intervention strategies will require combinational approaches,including bioengineered scaffolds,to support axon growth across tissue scarring and cystic cavitation.Previously,we demonstrated that implantation of a microporous type-I collagen scaffold into an experimental model of SCI was capable of supporting functional recovery in the absence of extensive implant–host neural tissue integration.Here,we demonstrate the reactive host cellular responses that may be detrimental to neural tissue integration after implantation of collagen scaffolds into unilateral resection injuries of the adult rat spinal cord.Immunohistochemistry demonstrated scattered fibroblast-like cell infiltration throughout the scaffolds as well as the presence of variable layers of densely packed cells,the fine processes of which extended along the graft–host interface.Few reactive astroglial or regenerating axonal profiles could be seen traversing this layer.Such encapsulation-type behaviour around bioengineered scaffolds impedes the integration of host neural tissues and reduces the intended bridging role of the implant.Characterization of the cellular and molecular mechanisms underpinning this behaviour will be pivotal in the future design of collagen-based bridging scaffolds intended for regenerative medicine. | Haktan Altinova Sebastian Hammes Moniek Palm Jose Gerardo-Nava Pascal Achenbach Ronald Deumens Emmanuel Hermans Tobias Fuhrmann Arne Boecker Sabien Geraldine Antonia van Neerven Ahmet Bozkurt Joachim Weis Gary Anthony Brook | 2019 | Regenerative Biomaterials2019，6，2： | 4 |
| 2 | 作为添加剂的颗粒状有机硅树脂在热塑性塑料中的应用显示文摘描述了一种以超高分子量(uhmw)的聚二甲基硅氧烷(PDMS)为基料的新型、多功能固体有机硅添加剂,着重描述了这些新型颗粒状有机硅树脂作为添加剂应用于热塑性塑料挤出。通过实例说明了颗粒状有机硅树脂能非常有效地改善热塑性塑料的加工性和流动性,尤其适用于充填的聚烯烃混合物。此外,它们能进一步提高冲击强度和抗张强度等机械性能,并且对于改善表面光滑性和抗磨损性也十分有效。 | Rudolf Hager Michael Geck Oliver Fuhrmann | 2004 | 塑料助剂2004，，6： | 3 |
| 3 | Automated classification of duodenal imagery in celiac disease using evolved Fourier feature vectors显示文摘 | Andreas Vécsei Thomas Fuhrmann Michael Liedlgruber Leonhard Brunauer Hannes Payer Andreas Uhl | 2009 | Computer Methods and Programs in Biomedicine2009，，2： | 2 |
| 4 | Experimental proof of Joule heating-induced switched-back regions in OLEDs显示文摘Organic light-emitting diodes(OLEDs)have become a major pixel technology in the display sector,with products spanning the entire range of current panel sizes.The ability to freely scale the active area to large and random surfaces paired with flexible substrates provides additional application scenarios for OLEDs in the general lighting,automotive,and signage sectors.These applications require higher brightness and,thus,current density operation compared to the specifications needed for general displays.As extended transparent electrodes pose a significant ohmic resistance,OLEDs suffering from Joule self-heating exhibit spatial inhomogeneities in electrical potential,current density,and hence luminance.In this article,we provide experimental proof of the theoretical prediction that OLEDs will display regions of decreasing luminance with increasing driving current.With a two-dimensional OLED model,we can conclude that these regions are switched back locally in voltage as well as current due to insufficient lateral thermal coupling.Experimentally,we demonstrate this effect in lab-scale devices and derive that it becomes more severe with increasing pixel size,which implies its significance for large-area,high-brightness use cases of OLEDs.Equally,these non-linear switching effects cannot be ignored with respect to the long-term operation and stability of OLEDs;in particular,they might be important for the understanding of sudden-death scenarios. | Anton Kirch Axel Fischer Matthias Liero Jurgen Fuhrmann Annegret Glitzky Sebastian Reineke | 2020 | Light(Science & Applications)2020，9，1： | 2 |
| 5 | Genomic rearrange- ments in OPAl are frequent in patients with autosomal domi- nant optic atrophy 显示文摘 | Fuhrmann N Alavi MV Bitoun P | 2009 | Med Genet2009，46，8： | 1 |
| 6 | Arsenic distribution and speciation in the fronds of the hyperaceumulator Pteris vittata显示文摘 | Lombi E Zhao F J Fuhrmann M | 2002 | New Phytologist2002，156，2： | 1 |
| 7 | Assessment of quality of lifein patients undergoing orthognathic surgery 显示文摘 | Bock JJ Odemar F Fuhrmann RA | 2009 | J Orofac Orthop2009，70，5： | 1 |
| 8 | High- resolution array comparative genomic hybridization of single micrometastatic tumor cells 显示文摘 | Fuhrmann C Schmidt-Kittler O Stoecklein NH | 2008 | Nucleic Acids Res2008，36，7： | 1 |
| 9 | Biphoton-indueed refractive index change in 4-amino-4' -nitroazobenzene/polycarbonate 显示文摘 | BACH H ANDERLE K FUHRMANN T | 1996 | J Phys Chem1996，100，： | 1 |
| 10 | Digital transversal slice imaging in dentalmaxillofacial radiology: from pantomography to cone-beam computed tomography 显示文摘 | Fuhrmann A Schulze D Rother U | 2003 | Int J Comput Dent2003，6，2： | 1 |
| 11 | Mcta-analysis of heart valve abnormalities in Parkinson's disease patients treated with do- pamine agonists显示文摘 | Simonis G Fuhrmann JT Strasser RH | 2007 | Mov Disord2007，22，13： | 1 |
| 12 | Derivation of oo- eytes from mouse embryonic stem cells 显示文摘 | Htibner K Fuhrmann G Christenson LK et at | 2003 | Science2003，300，5623： | 1 |
| 13 | Association between mycophenolic acid 12-h trough levels and clinical endpoints inpatients with autoimmune disease on mycophenolatemofetil显示文摘 | NEUMANN I FUHRMANN H FANG I F | 2008 | Nephrol Dial Transplant2008，23，11： | 1 |
| 14 | Transmit beamforming for MIMO radar systems using signal cross-correlation 显示文摘 | Fuhrmann D Antonio G S | 2008 | IEEE Transactions on Aerospace and Electronic Systems2008，44，1： | 1 |
| 15 | Current practice in conventiontal and Digital intraoral radiography:problems and solutions 显示文摘 | Fuhrmann AW | 2006 | Int J Corn- put Dent2006，9，1： | 1 |
| 16 | New POU dimer configuration mediates antagonistic control of an osteopontin preimplantation enhancer by Oct-4 and Sox-2 显示文摘 | Botquin V Hess H Fuhrmann G | 1998 | Genes Dev1998，12，13： | 1 |
| 17 | Crosslinkable polymers for nanocrystal stabilization显示文摘 | Fuhrmann K Gauthier M A Leroux J C | 2010 | J Contr Rel2010，148，： | 1 |
| 18 | Maximum likelihood narrow band direction finding and the EM algorithm 显示文摘 | MILLER M I FUHRMANN D R | 1990 | IEEE Acoustics Speech and Signal Processing1990，38，9： | 1 |
| 19 | Derivation of oocytes from embryonic stem cells显示文摘 | Hubner K Fuhrmann G ChristensonL K | 2003 | Science2003，300，： | 1 |
| 20 | A parametric method for determining the number of signals in narrow-band direction finding 显示文摘 | Wu Q Fuhrmann D R | 1991 | IEEE Trans on Signals Processing1991，39，8： | 1 |
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