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| 1 | Gastric intestinal metaplasia is associated with gastric dysplasia but is inversely correlated with esophageal dysplasia显示文摘AIM To determine which clinical factors might be associated with gastric intestinal metaplasia(IM) in a North American population.METHODS Pathology and endoscopy databases at an academicmedical center were reviewed to identify patients with and without gastric IM on biopsies for a retrospective cohort study. Patient demographics, insurance status, and other clinical factors were reviewed.RESULTS Four hundred and sixty-eight patients with gastric IM(mean age: 61.0 years ± 14.4 years, 55.5% female) and 171 without gastric IM(mean age: 48.8 years ± 20.8 years, 55.0% female) were compared. The endoscopic appearance of atrophic gastritis correlated with finding gastric IM on histopathology(OR = 2.05, P = 0.051). Gastric IM was associated with histologic findings of chronic gastritis(OR = 2.56, P < 0.001), gastric ulcer(OR = 6.97, P = 0.015), gastric dysplasia(OR = 6.11, P = 0.038), and gastric cancer(OR = 6.53, P = 0.027). Histologic findings of Barrett's esophagus(OR = 0.28, P = 0.003) and esophageal dysplasia(OR = 0.11, P = 0.014) were inversely associated with gastric IM. Tobacco use(OR = 1.73, P = 0.005) was associated with gastric IM.CONCLUSION Patients who smoke or have the endoscopic finding of atrophic gastritis are more likely to have gastric IM and should have screening gastric biopsies during esophagogastroduodenoscopy(EGD). Patients with gastric IM are at increased risk for having gastric dysplasia and cancer, and surveillance EGD with gastric biopsies in these patients might be reasonable. | Justin M Gomez James T Patrie Wissam Bleibel Jeanetta W Frye Bryan G Sauer Vanessa M Shami Edward B Stelow Christopher A Moskaluk Andrew Y Wang | 2017 | World Journal of Gastrointestinal Endoscopy2017，9，2： | 3 |
| 2 | Overexprcssion of tumor necrosis factor- alpha activites both anti and proapoptosis pathways in the myocardium 显示文摘 | Kubota T Miyagishima M Frye CS | 2001 | J Mol Cell Cardiol2001，33，7： | 2 |
| 3 | The Invisible Hand and the Grabbing Hand 显示文摘 | Frye T Shleifer A | 1997 | The American Economic Review1997，87，2： | 1 |
| 4 | Dilated cardiomyopathy in transgenic mice with cardiac-specific overexpression of tumor necrosis factor-alpha显示文摘 | KUBOTA T MCTIEMAN C F FRYE C S | 1997 | Circ Res1997，81，： | 1 |
| 5 | Cardiac-specific overexpression of TNF-α causes lethal myocarditis in transgenic mice 显示文摘 | Kubota T Metieman C F~ Frye C S | 1997 | J Card Fail1997，3，2： | 1 |
| 6 | Open-label aripiprazole in the treatment of acute bipolar depression : a prospective pilot trial显示文摘 | MCELROY SL SUPPES T FRYE MA | 2007 | J Affect Disord2007，101，13： | 1 |
| 7 | Overexpression of tumor necrosis factor - alpha activates both anti - and pro - apoptotic pathways in the myocardium 显示文摘 | Kubota T Miyagishima M Frye CS | 2001 | J Mol Cell Cardiol2001，33，7： | 1 |
| 8 | The invisible hand and the grabbing hand显示文摘 | Frye T Shleifer A | 1997 | American Economic Review1997，87，2： | 1 |
| 9 | Anti - tumor necrosis factor - alphe antibody limits heart failure in a transgenic model显示文摘 | Kadokami T Frye C Lemster B | 2001 | Circulations2001，104，： | 1 |
| 10 | The Invisible Hand and the Grabbing Hand显示文摘 | Frye T Shleifer A | | 0，，02： | 1 |
| 11 | The Invisible Hand and the Grabbing Hand 显示文摘 | Frye T Shleifer A | 1997 | American Economic Review1997，87，2： | 1 |
| 12 | Subsurface gas hydrates in the northern Gulf of Mexico显示文摘 | Boswell R Collett T S Frye M | 2012 | Marine and Petroleum Geology2012，34，1： | 1 |
| 13 | Effect of St John's Wort on imatinib mesylate pharmacokinetics&ast显示文摘 | Frye R Fitzgerald S Lagattuta T | 2004 | Clinical Pharmacology&Therapeutics2004，76，4： | 1 |
| 14 | The invisible Hand and the Grabbing hand 显示文摘 | FRYE T SHLE1FER A | 1997 | American Economic Review1997，，87： | 1 |
| 15 | Vitamin E biopotency:comparison of various‘natural-derived’and chemically synthesized-tocopherols显示文摘 | Scherf H Machlin L J Frye T M | 1996 | Animal Food Science Technology1996，59，13： | 1 |
| 16 | Analyzing organic vapors in exhaled breath using a suHace acoustic wave sensor array with preconcentration: Selectionand characterization of the preconcentrator adsorbent显示文摘 | Groves W A Zellers E T Frye G C | 1998 | Analytica Chimica Acta1998，371，23： | 1 |
| 17 | Epithelial defensins impair adenoviral infection:implication for adenovirus-mediated gene therapy显示文摘 | GROOP R FRYE M WAGNER T O | 1999 | Hum Gene Ther1999，10，6： | 1 |
| 18 | Overexpression of tumor necrosis factor-α activates both anti and pro-apoptotic pathways in the myocardium显示文摘 | Kubota T Miyagishima M Frye C | 2001 | J Mol Cell Cardiol2001，33，： | 1 |
| 19 | Anti tumor necrosis factor -alpha antibody limits heart failure in a transgenic model显示文摘 | Kadokami T Frye C Lemster B | 2001 | Circulation2001，104，： | 1 |
| 20 | Analysis of the systemic and intrathecal humoral immune response in progressive multiJbca| leukoencephalopathy显示文摘 | Weber T Trebst C Frye S | 1997 | Infect Dis1997，176，1： | 1 |
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