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| 1 | Gastric intestinal metaplasia is associated with gastric dysplasia but is inversely correlated with esophageal dysplasia显示文摘AIM To determine which clinical factors might be associated with gastric intestinal metaplasia(IM) in a North American population.METHODS Pathology and endoscopy databases at an academicmedical center were reviewed to identify patients with and without gastric IM on biopsies for a retrospective cohort study. Patient demographics, insurance status, and other clinical factors were reviewed.RESULTS Four hundred and sixty-eight patients with gastric IM(mean age: 61.0 years ± 14.4 years, 55.5% female) and 171 without gastric IM(mean age: 48.8 years ± 20.8 years, 55.0% female) were compared. The endoscopic appearance of atrophic gastritis correlated with finding gastric IM on histopathology(OR = 2.05, P = 0.051). Gastric IM was associated with histologic findings of chronic gastritis(OR = 2.56, P < 0.001), gastric ulcer(OR = 6.97, P = 0.015), gastric dysplasia(OR = 6.11, P = 0.038), and gastric cancer(OR = 6.53, P = 0.027). Histologic findings of Barrett's esophagus(OR = 0.28, P = 0.003) and esophageal dysplasia(OR = 0.11, P = 0.014) were inversely associated with gastric IM. Tobacco use(OR = 1.73, P = 0.005) was associated with gastric IM.CONCLUSION Patients who smoke or have the endoscopic finding of atrophic gastritis are more likely to have gastric IM and should have screening gastric biopsies during esophagogastroduodenoscopy(EGD). Patients with gastric IM are at increased risk for having gastric dysplasia and cancer, and surveillance EGD with gastric biopsies in these patients might be reasonable. | Justin M Gomez James T Patrie Wissam Bleibel Jeanetta W Frye Bryan G Sauer Vanessa M Shami Edward B Stelow Christopher A Moskaluk Andrew Y Wang | 2017 | World Journal of Gastrointestinal Endoscopy2017，9，2： | 3 |
| 2 | Overexprcssion of tumor necrosis factor- alpha activites both anti and proapoptosis pathways in the myocardium 显示文摘 | Kubota T Miyagishima M Frye CS | 2001 | J Mol Cell Cardiol2001，33，7： | 2 |
| 3 | Overexpression of tumor necrosis factor - alpha activates both anti - and pro - apoptotic pathways in the myocardium 显示文摘 | Kubota T Miyagishima M Frye CS | 2001 | J Mol Cell Cardiol2001，33，7： | 1 |
| 4 | Neuronal pathology in the hippocampal area of patients with bipolar disorder: a study with proton magnetic resonance spectroscopic imaging 显示文摘 | Bertolino A Frye M Callicott JH | 2003 | Biol Psychiatry2003，53，10： | 1 |
| 5 | Effect of feeding high levels of protein and calcium in rat rations on magnesium defieieney syndrome显示文摘 | COLBY R W FRYE C M | 1951 | American Journal of Physiology1951，166，： | 1 |
| 6 | Phase II multi-institutional trial of the histone deacetylase inhibitor romidepsin as monotherapy for patients with cutaneous T-cell lymphoma显示文摘 | PIEKARZ RL FRYE R TURNER M | 2009 | J Clin Oncol2009，27，32： | 1 |
| 7 | Analysis of flexibly connection frames显示文摘 | FRYE M J MORRIS G A | 1975 | Canada Journal of Civil Engineering1975，2，3： | 1 |
| 8 | Extraesophageal GERD显示文摘 | FRYE J W VAEZI M F | 2008 | Gsatroenterol Clin North Am2008，37，： | 1 |
| 9 | Subsurface gas hydrates in the northern Gulf of Mexico显示文摘 | Boswell R Collett T S Frye M | 2012 | Marine and Petroleum Geology2012，34，1： | 1 |
| 10 | Therapeutic Recreation,its Theory,Philosophy,and Practice显示文摘 | FRYE V PETERS M | 1974 | American Journal of Physical Medicine&Rehabilitation1974，53，3： | 1 |
| 11 | MYC in mammalian epidermis: how can an onengene stimulate differentiation 显示文摘 | Watt FM Frye M Benitah SA | 2008 | Nat Rev Cancer2008，8，3： | 1 |
| 12 | Alliance Portfolios and Shareholder Value in Post-IPO Firms: The Moderating Roles of Portfolio Structure and Firm-Level Uneertainty显示文摘 | MOURI N SARKAR M B FRYE M | 2012 | Journal of Business Venturing2012，27，3： | 1 |
| 13 | Comparison of coronary revascularization procedures in octogenarians: a systematic review and meta-analysis 显示文摘 | McKellar S H Brown M L Frye R L | 2008 | Nat Clin Praet Cardiovasc Med2008，5，11： | 1 |
| 14 | Combined PET/CT image characteristics for radiotherapy tumor response in lung cancer显示文摘 | Vaidya M Creach KM Frye J | 2011 | Radiother On-col2011，16，： | 1 |
| 15 | Vitamin E biopotency:comparison of various‘natural-derived’and chemically synthesized-tocopherols显示文摘 | Scherf H Machlin L J Frye T M | 1996 | Animal Food Science Technology1996，59，13： | 1 |
| 16 | The performance of bank-managed mutual funds显示文摘 | Frye M B | 2001 | Journal of Financial Research2001，24，3： | 1 |
| 17 | Salmonella enterica serovar Typhimurium re quires the Lpf,Pef, and Tafi fimbriae for biofilm for- mation on HEp-2 tissue culture cells and chicken in- testinal epithelium 显示文摘 | LEDEBOER N A FRYE J G MCCLELLAND M | 2006 | Infect Immun2006，74，6： | 1 |
| 18 | Epithelial defensins impair adenoviral infection:implication for adenovirus-mediated gene therapy显示文摘 | GROOP R FRYE M WAGNER T O | 1999 | Hum Gene Ther1999，10，6： | 1 |
| 19 | Neuronal pathology in the hippocampal area of patients with bipolar disorder: a study with proton magnetic resonance spectroscopic imaging 显示文摘 | Bertolino A Frye M Callicott J H | 2003 | Biol Psychiatry2003，53，10： | 1 |
| 20 | Overexpression of tumor necrosis factor-α activates both anti and pro-apoptotic pathways in the myocardium显示文摘 | Kubota T Miyagishima M Frye C | 2001 | J Mol Cell Cardiol2001，33，： | 1 |
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