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| 1 | 纳米金属镍的制备与磁性研究显示文摘采用微波polyol还原法成功地制备了单分散5~10nm镍球颗粒,由高分辨率电子显微镜(HRTEM)观察证实,5nm镍的颗粒面间距为0.2033nm,与文献报道的镍的FCC结构(100)面的0.2034nm比较吻合[JCPDS:4-850]。通过在不同温度下测量零场冷(ZFC)和场冷(FC,1600kA·m-1)所获样品的磁滞回线,发现纳米镍从铁磁性过渡到超顺磁性的相变温度Tpt=100K,在Tpt温度以上,磁滞回线都发生偏置。 | 刘先松 陈鲁国 黄凯 周圣强 Udi Meridor Aviad Frydman Aharon Gedanken | 2008 | 稀有金属材料与工程2008，37，3： | 6 |
| 2 | Protein misfolding in neurodegenerative diseases:implications and strategies显示文摘A hallmark of neurodegenerative proteinopathies is the formation of misfolded protein aggregates that cause cellular toxicity and contribute to cellular proteostatic collapse.Therapeutic options are currently being explored that target different steps in the production and processing of proteins implicated in neurodegenerative disease,including synthesis,chaperone-assisted folding and trafficking,and degradation via the proteasome and autophagy pathways.Other therapies,like mTOR inhibitors and activators of the heat shock response,can rebalance the entire proteostatic network.However,there are major challenges that impact the development of novel therapies,including incomplete knowledge of druggable disease targets and their mechanism of action as well as a lack of biomarkers to monitor disease progression and therapeutic response.A notable development is the creation of collaborative ecosystems that include patients,clinicians,basic and translational researchers,foundations and regulatory agencies to promote scientific rigor and clinical data to accelerate the development of therapies that prevent,reverse or delay the progression of neurodegenerative proteinopathies. | Patrick Sweeney Hyunsun Park Marc Baumann John Dunlop Judith Frydman Ron Kopito Alexander McCampbell Gabrielle Leblanc Anjli Venkateswaran Antti Nurmi Robert Hodgson | 2017 | Translational Neurodegeneration2017，6，1： | 4 |
| 3 | 微波辅助polyol法制备的纳米镍颗粒显示文摘采用微波辅助polyol还原法制备了单分散的纳米Ni颗粒。分别用X射线衍射(XRD)和透射电镜(TEM)观测样品的相结构和微观形貌,用振动样品磁强计(VSM)测试Ni颗粒的磁性。XRD显示样品为面心立方结构,TEM观察显示金属镍颗粒的形貌是理想的球型。当把反应温度提高到400℃,并且在实验过程中加入适量的PVP时,发现镍颗粒呈现出一种毛茸茸的多毛形态,这种分散均匀的单一态形貌类似于纳米头发的结构。同时,VSM测试结果表明球型纳米Ni颗粒具有典型的铁磁性。 | 徐小兵 刘先松 Udi Meridor Aviad Frydman Aharon Gedanken | 2008 | 磁性材料及器件2008，39，6： | 4 |
| 4 | Late onset fulminant Wilson's disease:A case report and review of the literature显示文摘Wilson’s disease(WD)is an autosomal recessive inherited disorder of hepatic copper metabolism.WD can be present in different clinical conditions,with the most common ones being liver disease and neuropsychiatric disturbances.Most cases present symptoms at<40years of age.However,few reports exist in the literature on patients in whom the disease presented beyond this age.In this report,we present a case of late onset fulminant WD in a 58-year-old patient in whom the diagnosis was established clinically,by genetic analysis of the ATP7B gene disclosing rare mutations(G1099S and c.1707+3ins T)as well as by high hepatic copper content.We also reviewed the relevant literature.The diagnosis of WD with late onset presentation is easily overlooked.The diagnostic features and the geneticbackground in patients with late onset WD are not different from those in patients with early onset WD,except for the age.Effective treatments for this disorder that can be fatal are available and will prevent or reverse many manifestations if the disease is discovered early. | Ella Weitzman Orit Pappo Peretz Weiss Moshe Frydman Yael Haviv-Yadid Ziv Ben Ari | 2014 | World Journal of Gastroenterology2014，20，46： | 2 |
| 5 | Ig G4-related disease manifesting as an acute gastric-pericardial fistula显示文摘Ig G4-related disease is a recently recognized entity linked initially to autoimmune pancreatitis and has been subsequently described in nearly every organ system. Men over the age of 50 represent the most affected demographic group and a comprehensive set of diagnostic criteria has been developed to aid treating clinicians. Though elevated levels of Ig G4 in the serum are suggestive of the disease, definitive diagnosis is made on histopathology. Treatment is tailored to the clinical presentation with corticosteroid therapy known to have proven efficacy. Gastric manifestations of the Ig G4-related disease primarily come in two varieties, notably chronic ulceration or pseudotumor formation. Autoimmune pancreatitis conveys increased risk for Ig G4-related disease of the stomach, which is independent of Helicobacter pylori status. In this case report, we present an acute gastric-pericardial fistula secondary to Ig G4-related disease that required urgent operative management. To our knowledge, this is the first report in the medical literature describing this complication of Ig G4-related disease. | James Frydman Shahar Grunner Yoram Kluger | 2014 | World Journal of Gastroenterology2014，20，44： | 2 |
| 6 | 单分散Ni球制备及Ni/NiO的磁性研究显示文摘使用微波辅助Poly方法制备了直径范围在100nm~180nm单分散的Ni球,用磁力显微镜(MFM)测其磁结构。进一步对Ni球表面氧化获得了高度球化的NicoreNiOshell结构,采用XRD,TEM,XPS和EDAX对其进行了测量分析,并用VSM和SQUID进一步讨论了铁磁/反铁磁的界面耦合效应。同时,估算了磁性交换偏置耦合场与颗粒尺寸的关系。 | 刘先松 周圣强 黄凯 Udi Meridor Aviad Frydman Aharon Gedanken | 2006 | 稀有金属材料与工程2006，35，9： | 2 |
| 7 | Interactions between natural polyamines and tRNA: an 15N NMR analysis 显示文摘 | FRYDMAN L ROSSOMANDO P C FRYDMAN V | 1992 | Proc Natl Acad Sci USA1992，89，19： | 1 |
| 8 | Labor induction in women at term with mifepristone (RU486):a double-blind, randomized, placebo controlled study显示文摘 | Frydman R Lelaidier G Baton Saint Mleux G | 1992 | Obstet Gynecol1992，80，6： | 1 |
| 9 | Anti-Mullerian hormone concentrations in the follicular fluid of the preovulatory follicle are predictive of the implantation potential of the ensuing embryo obtained by in vitro fertilization显示文摘 | Fanchin R Mendez LD Frydman N Gougeon A di Clemente N Frydman R Taieb J | 2007 | J Clin Endocrinol Metab2007，92，： | 1 |
| 10 | The influence of vegetation on soil strength显示文摘 | OPERSTEIN V FRYDMAN S | 2000 | Proceedings of the ICE-Ground Improvement2000，4，2： | 1 |
| 11 | Induction of DNA topoisomerase Ⅱ-mediated DNA cleavage by β-lapachone and related naphtnoquinones显示文摘 | Frydman B Marton LJ Sun JS | 1997 | Cancer res1997，57，4： | 1 |
| 12 | Different polyamine analogue effects in four human breast cancer cell lines 显示文摘 | Holst C M Frydman B Marton L J | 2006 | Toxicology2006，223，12： | 1 |
| 13 | Genetic aspects of Wilsons disease显示文摘 | Frydman M | 1990 | J Gastroenterol Hepatol1990，5，4： | 1 |
| 14 | Bis (Ethyl)-cis-6, 7-dehydrospermine: a new drug for treatment and prevention of Cryptosporidium parvum infection of mice deficient in T-cell receptor alpha显示文摘 | Waters WR Frydman B Matron LJ | 2000 | Antimicrob Agents Chemother2000，44，10： | 1 |
| 15 | Expression of Na +/I - symporter and Pendred syndrome genes in trophoblast cells显示文摘 | Bidart JM Lacroix L Evain- Brion D Caillou B Lazar V Frydman R Bellet D Filetti S Schlumberger M | 2000 | J Clin Endocrinol Metab2000，85，11： | 1 |
| 16 | Analysis of electrochemical noise by power spectral density applied to corrosion studies显示文摘 | Bertocci U Frydman J Gabrielli C | 1998 | J Electrochemist Soc1998，145，8： | 1 |
| 17 | Uhrafast 2D NMR spectroscopy using sinusoidal gradients: principles and Ex Vivo brain investigations显示文摘 | Noa Sela Hadassa Degani Lucio Frydman | 2004 | Magnetic Resonance in Med2004，52，： | 1 |
| 18 | Genetic and bio- chemical analyses of Israeli osteogenesis imperfecta patients 显示文摘 | Ries-Levavi L Ish-Shalom T Frydman M | 2004 | Hum Mutat2004，23，4： | 1 |
| 19 | When does Privatization work? The Impact of Private Ownership on Corporate Performance in the Transition Economies显示文摘 | Frydman Roman Gray Marek Hessel Rapaczynski | 1999 | The Quarterly Journal of Economics1999，，114： | 1 |
| 20 | Nerve injuries显示文摘 | Frydman WL | | 0，，： | 1 |
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