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	题名	作者	年代	出处	被引量
1	Soluble HLA-G molecules are increased in lymphoproliferative disorders 显示文摘	Sebti Y Le Friec G Pangault C	2003	Hum Immunol2003，64，9：	1
2	Capacity of myeloid and plasmacytoid dendritic cells especially at mature stage to express and secrete HLA - G molecules 显示文摘	Le Friec G Gins F Sebti Y Guilloux V Panganlt C Fauchet R Amiot L	2004	J Leukoc Biol2004，76，6：	1
3	Detection of HLA - G in serum and graft biopsy associated with fewer acute rejections following combined liver-kidney transplantation: possible implications for monitoring patients 显示文摘	Creput C Le Friec G Bahri R Amiot L Charpentier B Carosella E Rouas - Freiss N Durrbach A	2003	Hum Immunol2003，64，11：	1
4	Lung macrophages and dendritic cells express HLA - G molecules in pulmonary diseases 显示文摘	Pangault C Le Friec G Caulet - Maugendre S Lena H Amiot L Guilloux V Onno M Fauchet R	2002	Hum Immunol2002，63，2：	1
5	C3 a modulates IL-lb secretion in human monocytes by regulating atp efflux and subsequent nlrp 3 inflammasome activation 显示文摘	Asgari E Le friec G Yamamoto H	2013	Blood2013，122，20：	1
6	A complement a day keeps the Fox (p3) away显示文摘	Le Friec G KohlJ Kemper C	2013	Nat Immunol2013，14，2：	1
7	The CD46-Jagged 1 intera-ction is critical for human TH1 immunity 显示文摘	Le Friec G Sheppard D Whiteman P	2012	Nat Immunol2012，13，12：	1
8	Lung macrophages and dendritic cells express HLA-G mole c2ules in pulmonary diseases 显示文摘	Pangauh C Le Friec G Caulet MS	2002	Hum Immunol2002，63，2：	1
9	Detection of HLAG in serum and graft biopsy associated with fewer acute rejections following combined Iiver-kidney transplantation: possible implications for monitoring patients显示文摘	Creput C Le Friec G Bahri R	2003	Hum Immunol2003，64，：	1
10	The Thl life cycle: molecular control of IFN-%, to IL-10 switching显示文摘	Cope A Le Friec G Cardone J	2011	Trends Immuno 12011，32，6：	1
11	Capacity of myeloid and plasmacytoid dendritic cells especially at mature stage to express and secrete HLA-G molecules显示文摘	Le Friec GL Gros F Sebti Y	2004	J Leuk Biol2004，76，：	1
12	Modulation of HLA-G antigens expression in myelomonoeytic cells 显示文摘	Onno M Le Friec G Pangault C	2000	Hum Immunol2000，61，：	1
13	Modulation of HLA-G antigensexpression by human cytomegalovirus:specific induction in activatedmacrophagas harboring human cytomegalovirus infection显示文摘	Onno M Pangault C Le Friec G	2000	Immunol2000，164，12：	1
14	Generation of a Double KO Mouse by Simultaneous Targeting of the Neighboring Genes Tmem176a and Tmem176b Using CRISPR/Cas9:Key Steps from Design to Genotyping显示文摘The CRISPR/Cas9 system has been tailored to a revolutionary genetic tool because of its remarkable simplicity and efficacy.While complex genome editing in the mouse since the 1990 s has been dominated by the use of embryonic stem(ES) cells,CRISPR/Cas9 now offers a versatile and fast approach to precisely modify virtually any DNA regions directly in mouse zygotes.Yet,this relative simplicity does not preclude a conscientious preparatory work that is often neglected when initiating a project.Here,we describe the key steps leading to successful generation of a double knockout(KO) mouse by simultaneously targeting two homolog genes,Tmem176 a and Tmem176 b,which are located in the same genomic locus.Additionally,we show that similar efficiency can be obtained in a mixed genetic background or directly in the C57BL/6 inbred strain.Thus,presented as a detailed case study that should be helpful to the non-specialists,we focus on the genotyping strategy to anticipate the various possibilities.	Aurélie Lemoine Gaёlle Chauveau-Le Friec Francina Langa Cédric Louvet	2016	Journal of Genetics and Genomics2016，43，5：	1
15	Complement regulator CD46 temporally regulates cytokine production by conventional and unconventional T cells显示文摘	Cardone J Le Friec G Vantourout P	2010	Nat Immunol2010，11，9：	1
16	Detection of HLA-G in serumand graft biopsy associated with fewer acute rejections following com-bined liver-kidney transplantation : possible implications for monito-ring patients显示文摘	Creput C Le Friec G Bahri R	2003	Hum Immunol2003，64，11：	1
17	The CD46-Jagged 1 in- teraction is critical for human TH1 immunity显示文摘	Le Friec G Sheppard D Whiteman P	2012	Nature Immunology2012，13，：	1
18	Complement regu- lator CD46 temporally regulates cytokine production by conven- tional and unconventional T ceils 显示文摘	Cardone J Le Friec G Vantourout P et 01	2010	Nat Immunol2010，11，9：	1
19	Modulation of HLA-G antigens expression by human cytomegalovirus:specific induction in activated macrophages harboring human cytomegalovirus infection显示文摘	Onno M Pangault C Le Friec G	2000	Immunol2000，164，12：	1
20	Modulation of HLA-G antigens expression by human cytomegalovirus:specific induction in activated macrophages harboring human cytomegalovirus infection显示文摘	Onno M Pangault C Le Friec G		0，，12：	1

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