维普期刊资源整合服务平台（V6.5）

155篇 您的检索式：作者名="Cardone J"

选中清除导出查看参考文献查看引证文献引用追踪共8页首页上一页第1页下一页末页 /8 跳转

	题名	作者	年代	出处	被引量
1	Evidence for the involvement of NOD2 in regulating colonic epithelial cell growth and survival显示文摘AIM: To investigate the function of NOD2 in colonic epithelial cells (CEC). METHODS: A combination of in vivo and in vitro analyses of epithelial cell turnover in the presence and absence of a functional NOD2 protein and, in response to enteric Salmonella typhimurium infection, were used. shRNA interference was also used to investigate the consequences of knocking down NOD2 gene expression on the growth and survival of colorectal carcinoma cell lines. RESULTS:In the colonic mucosa the highest levels of NOD2 expression were in proliferating crypt epithelial cells. Muramyl dipeptide (MDP), that is recognized by NOD2, promoted CEC growth in vitro . By contrast,the growth of NOD2-deficient CECs was impaired. In vivo CEC proliferation was also reduced and apoptosis increased in Nod2-/- mice, which were also evident following enteric Salmonella infection. Furthermore, neutralization of NOD2 mRNA expression in human colonic carcinoma cells by shRNA interference resulted in decreased survival due to increased levels of apoptosis. CONCLUSION: These findings are consistent with the involvement of NOD2 protein in promoting CEC growth and survival. Defects in proliferation by CECs in cases of CD may contribute to the underlying pathology of disrupted intestinal homeostasis and excessive inflammation.	Sheena M Cruickshank Louise Wakenshaw John Cardone Peter D Howdle Peter J Murray Simon R Carding	2008	World Journal of Gastroenterology2008，14，38：	3
2	Meta-analysis of gray matter ab- normalities in autism spectrum disorder 显示文摘	Via E Padua J Cardoner N	2011	Arch Gen Psychiatry2011，68，4：	1
3	Gene frequenciesof the HPA-15(Gov)platelet alloantigen system in Brazilians显示文摘	Cardone J D Chiba A K Boturo-Neto E	2004	Transfus Med2004，14，6：	1
4	MiR-155 gene: A typical multifunctional microRNA显示文摘	Faraoni I Antonetti FR Cardone J	2009	Biochim Biophys Acta2009，1792，6：	1
5	Topical capsaiein for treatment of hemodialysis -related pruritus显示文摘	BRENEMAN D L CARDONE J S BLUMSACKLTLR F	1992	Am Acad Dermatol1992，26，：	1
6	Genome-wide strategies for detecting multiple loci that influence complex diseases显示文摘	Marchini J Donnelly P Cardon L R	2005	Nat Genet2005，37，4：	1
7	Practical modeling of hurricane surface wind fields显示文摘	Thompson E F Cardone V J	1996	Journal of Water- way Port Coastal and Ocean Engineering1996，122，4：	1
8	miR-155 gene: a typical multifunctional microRNA 显示文摘	Faraoni I Antonetti FR Cardone J	2009	Biochim Biophys Acta2009，1792，6：	1
9	The effects of human population structure on large genetic association studies 显示文摘	Marchini J Cardon LR Phillips MS	2004	Nat Genet2004，36，：	1
10	Impact of QuikSCAT Surface Marine Winds on Wave Hindcasting, Rosenstiel School of Marine and Atmospheric Science显示文摘	Cardone V J Cox A T Harris E L	2005	1-242005，124，：	1
11	Molecular characterisation of the Arabidopsis SBP-box genes显示文摘	Cardon G Hohmann S Klein J	1999	Gene1999，237，：	1
12	Topical capsaicin for treatment of hemodialysis-related pruritus 显示文摘	Breneman D L Cardone J S Blumsack R F	1992	J Am Acad Dermatol1992，26，1：	1
13	Plasticity in the developing auditory cortex: evidence from children with sensorineural hearing loss and auditory neuropathy spectrum disorder显示文摘	Cardon G Campbell J Sharma A	2012	J Am Acad Audiol2012，23，：	1
14	miR-155 gene : a typical multifunctional microRNA 显示文摘	Faraoni I Antonetti FR Cardone J	2009	Biochim Biophys Acta2009，1792，6：	1
15	miR-155 gene : a typical multifunetional mieroRNA 显示文摘	Faraoni I Antonetti FR Cardone J	2009	Bioehim Biophys Aeta2009，1792，：	1
16	SHIMMER:a spatial heterodyne spectrometer for remote sensing of earth's middle atmosphere显示文摘	Harlander J Roesler F L Cardon J G	2002	Appl Opt2002，41，7：	1
17	Kinetics of the coesite-quartz transition:application to the exhumation of ultrahigh-pressure rocks显示文摘	Perrillat J P Daniel I Lardeaux J M Cardon H		0，，：	1
18	miR-155 gene: A typi- cal muhifunctional microRNA 显示文摘	Faraoni I Antonetti FR Cardone J	2009	Biochim Biophys Acta2009，1792，6：	1
19	Population stratification and spurious allelic association显示文摘	Lon R Cardon Lyle J Palmer	2003	2003 (9357)2003，，9357：	1
20	T cell deficiency leads to cognitive dysfunction: implications for therapeutic vaccination for schizophrenia and other psychiatric conditions显示文摘	Kipnis J Cohen H Cardon M	2004	Proc Natl Acad Sci USA2004，101，21：	1

返回顶部每页显示：

共8页首页上一页第1页下一页末页 /8 跳转

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费

用户提示