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| 1 | Comparison between endoscopic sphincterotomy vs endoscopic sphincterotomy associated with balloon dilation for removal of bile duct stones:A systematic review and meta-analysis based on randomized controlled trials显示文摘AIM To compare gallstones removal rate and incidence of bleeding, pancreatitis, use of mechanical lithotripsy, cholangitis and perforation between isolated sphincterotomy vs sphincterotomy associated with balloon dilation of papilla in choledocholithiasis through the meta-analysis of randomized clinical trials. METHODS We conducted a systematic review according to the PRISMA guidelines. Literature search was restricted to randomized controlled trials(RCTs) on Med Line, Cochrane Library, LILACS, and EMBASE database platforms in July 2017. The manual search included references of retrieved articles. We extracted data focusing on outcomes: The primary endpoint was the stones removal rate; Secondary endpoints were rates of pancreatitis, bleeding, use of mechanical lithotripsy(ML), perforation and cholangitis. RESULTS Eleven RCTs with 1824 patients were included. EST was associated with more post-endoscopic retrograde cholangiopancreatography(ERCP) bleeding [FE RD-0.02, CI(-0.03,-0.00), I2 = 33%, P = 0.05] and more need of mechanical lithotripsy in general [RE RD-0.16, CI(-0.25,-0.06), I2 = 90%, P = 0.002] and in subgroup analysis of stones greater than 15 mm [RE RD-0.20, CI(-0.38,-0.02), I2 = 82%, P = 0.003]. Incidence of pancreatitis [FE RD-0.01, CI(-0.03, 0.01), I2 = 0, P = 0.36], cholangitis [FE RD-0.00, CI(-0.01, 0.01), I2 =0, P = 0.97] and perforation [FE RD-0.01, CI(-0.01, 0.00), I2 = 0, P = 0.23] was similar between the groups as well as similar stone removal rates in general [FE RD-0.01, CI(-0.01, 0.04), I2 = 0, P = 0.23] and pooled analysis of stones greater than 15 mm [FE RD-0.02, CI(-0.02, 0.07), I2 = 11%, P = 0.31]. CONCLUSION Through meta-analysis of randomized clinical trials we found that isolated sphincterotomy was associated with more post-ERCP bleeding and more need for mechanical lithotripsy. However, there was no statistical difference in the stone removal rate between isolated sphincterotomy and sphincterotomy associated with balloon dilation in the approach to remove gallstones. | Cesar Capel de Clemente Junior Wanderley Marques Bernardo Tomazo Prince Franzini Gustavo Oliveira Luz Marcos Eduardo Lera dos Santos Jonah Maxwell Cohen Diogo Turiani Hourneaux de Moura Fábio Ramalho Tavares Marinho Martin Coronel Paulo Sakai Eduardo Guimaraes Hourneaux de Moura | 2018 | World Journal of Gastrointestinal Endoscopy2018，10，8： | 8 |
| 2 | Endoscopic ultrasound-guided vs endoscopic retrograde cholangiopancreatography biliary drainage for obstructed distal malignant biliary strictures: A systematic review and meta-analysis显示文摘BACKGROUND For palliation of malignant biliary obstruction(MBO), the gold-standard method of biliary drainage is endoscopic retrograde cholangiopancreatography(ERCP)with the placement of metallic stents. Endoscopic ultrasound(EUS)-guided drainage is an alternative that is typically reserved for cases of ERCP failure.Recently, however, there have been robust randomized clinical trials(RCTs)comparing EUS-guided drainage and ERCP as primary approaches to MBO.AIM To compare EUS guidance and ERCP in terms of their effectiveness and safety in palliative biliary drainage for MBO.METHODS This was a systematic review and meta-analysis, in which we searched the MEDLINE, Excerpta Medica, and Cochrane Central Register of Controlled Trials databases. Only RCTs comparing EUS and ERCP for primary drainage of MBO were eligible. All of the studies selected provided data regarding the rates of technical and clinical success, as well as the duration of the procedure, adverse events, and stent patency. We assessed the risk of biases using the Jadad score and the quality of evidence using the Grading of Recommendations Assessment,Development and Evaluation criteria.RESULTS The database searches yielded 5920 records, from which we selected 3 RCTs involving a total of 222 patients(112 submitted to EUS and 110 submitted to ERCP). In the EUS and ERCP groups, the rate of technical success was 91.96%n and 91.81%, respectively, with a risk difference(RD) of 0.00%(95%CI:-0.07, 0.07;P = 0.97; I^2 = 0%). The clinical success was 84.81% and 85.53% in the EUS and ERCP groups, respectively, with an RD of-0.01%(95%CI:-0.12, 0.10; P = 0.90; I^2 =0%). The mean difference(MD) for the duration of the procedure was-0.12%(95%CI:-8.20, 7.97; P = 0.98; I^2 = 84%). In the EUS and ERCP groups, there were14 and 25 adverse events, respectively, with an RD of-0.06%(95%CI:-0.23, 0.12; P= 0.54; I^2 = 77%). The MD for stent patency was 9.32%(95%CI:-4.53, 23.18; P =0.19; I^2 = 44%). The stent dysfunction rate was significantly lower in the EUS t group(MD =-0.22%; 95 CI:-0.35,-0.08; P = 0.001; I^2 = 0%).CONCLUSION EUS represents an interesting alternative to ERCP for MBO drainage,demonstrating lower stent dysfunction rates compared with ERCP. Technical and clinical success, duration, adverse events and patency rates were similar. | Fernanda P Logiudice Wanderlei M Bernardo Facundo Galetti Vitor M Sagae Carolina O Matsubayashi Antonio C Madruga Neto Vitor O Brunaldi Diogo T H de Moura Tomazo Franzini Spencer Cheng Sergio E Matuguma Eduardo G H de Moura | 2019 | World Journal of Gastrointestinal Endoscopy2019，11，4： | 6 |
| 3 | 20例原发性脑脓肿立体定向治疗的临床观察显示文摘目的探讨立体定向引流技术治疗原发性脑脓肿的临床效果。方法回顾分析20例原发性脑脓肿患者立体定向治疗资料,脓液进行细菌培养病原体分析。结果本组病人无1例死亡,术前颅内压增高者症状很快消失,2例术后发生癫痫。随访1~15年,所有患者均未出现脓肿复发,局灶性神经功能缺损者病例症状完全消失。16例吸取脓液的细菌培养结果为阴性4,例培养阳性患者分别是葡萄球菌、β-溶血性链球菌、肺炎球菌和非溶血性链球菌。结论无菌的脑脓肿即使没有存活的细菌仍然可能表现出自我维持增长的病变趋势。立体定向引流治疗可通过吸取病灶内壁周围的感染刺激因子而达到治疗目的。 | 马辉 夏鹤春 付健敏 孙涛 贾培磊 Carlo Marras Angelo Franzini | 2010 | 宁夏医科大学学报2010，32，9： | 5 |
| 4 | γ-Glutamyltransferase activity in human atherosclerotic plaques—Biochemical similarities with the circulating enzyme显示文摘 | Maria Franzini Alessandro Corti Barbara Martinelli Antonella Del Corso Michele Emdin Giuliano F. Parenti Mattia Glauber Alfonso Pompella Aldo Paolicchi | 2008 | Atherosclerosis2008，，1： | 2 |
| 5 | Brainstem caverno-mas:long-term results of microsurgical resection in 52patients显示文摘 | Ferroli P Sinisi M Franzini A | 2005 | Neurosurgery2005，56，6： | 1 |
| 6 | Brainstem cavemomas: long- term results of microsurgical resection in 52 Patients 显示文摘 | Ferroli P Sinisi M Franzini A | 2005 | Neuresurgery2005，56，6： | 1 |
| 7 | Perceived peer norms, casual sex and AIDS risk prevention 显示文摘 | Winslow RW Franzini LW Hwang J | 1992 | J Appl Soc Psychol1992，22，23： | 1 |
| 8 | Role of m-icrovascular decompression in trigeminal neuralgia and multiple sclerosis显示文摘 | BROGGI G FERROLI P FRANZINI A | 1999 | Lancet1999，354，： | 1 |
| 9 | Opelative findings and out- comes of microvascular decompression for trigeminal neuralgia in 35 patients affected by multiple sclerosis 显示文摘 | Broggi G Fen'oli P Franzini A | 2004 | Neurosurgery2004，55，4： | 1 |
| 10 | Microvascular decompression for trigeminal neuralgia: Comments on a series of 250 case,including 10 paients with multiple sclerosis显示文摘 | BROGGI G FERROLI P FRANZINI A | 2000 | J Neurol Neurosurg Psychiatry2000，68，： | 1 |
| 11 | Deep-brain stimulation of the nucleus accumbens in obsessive compulsive disorder: clini- cal, surgical and electrophysiological considerations in two con- secutive patients显示文摘 | Franzini A Messina G Gambini G | 2010 | Neurol Sci2010，31，3： | 1 |
| 12 | Supratentorial cavernous angiomas and epileptic seizures : preoperative course and postoperative outcome显示文摘 | Casazza M Broggi G Franzini A | 1996 | Neurosurgery1996，39，1： | 1 |
| 13 | ADMA is independent- ly related to flow-mediated vasodilation in subjects at low cardiovas- culm risk 显示文摘 | Ardigo D St eblinger M Franzini L | 2007 | Eur J Clin lnvest2007，37，4： | 1 |
| 14 | Brainstem cavernomas: long term results of mierosurgical resection in 52 patients显示文摘 | Ferroli P Sinisi M Franzini A | 2005 | Neurosurgery2005，56，6： | 1 |
| 15 | Brainstem cavernomas:long-term results of microsurgical resection in 52 patients显示文摘 | Ferroli P Sinisi M Franzini A | 2005 | Neurosurgery2005，56，6： | 1 |
| 16 | Linear pontine and trigeminal root lesions and trigeminal neuralgia显示文摘 | Ferroli P Farina L Franzini A | 2001 | J Arch Neurol2001，58，： | 1 |
| 17 | Heath care costs and utilization of vul- nerable elderly people reported to Adult Protective Services for self-- neglect显示文摘 | Franzini I Dyer CB | 2008 | J Am Geriatr Soc2008，56，4： | 1 |
| 18 | A Simple Method to Evaluate the Matrix Effects in X-ray Fluorescence Analysis显示文摘 | FRANZINI M LEONI L SAITfA M | 1972 | X-ray Spectrometry1972，1，4： | 1 |
| 19 | Hypothalamic stimulation for intractable cluster headache:long-term experience显示文摘 | Leone M Franzini A Broggi G | 2006 | Neurology2006，67，1： | 1 |
| 20 | Does the presence ofapontine trigeminal lesion represent an absolute contra-indication for microvascular decompression in drug re-sistant trigeminal neuralgia显示文摘 | Ferroli P Franzini A Farina L | 2002 | J Neurol Neurosurg Psy-chiatry2002，72，： | 1 |
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