|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Comparison of inhaled milrinone, nitric oxide and prostacyclin in acute respiratory distress syndrome显示文摘AIM To evaluate the safety and efficacy of inhaled milrinone in acute respiratory distress syndrome(ARDS).METHODS Open-label prospective cross-over pilot study where fifteen adult patients with hypoxemic failure meeting standard ARDS criteria and monitored with a pulmonary artery catheter were recruited in an academic 24-bed medico-surgical intensive care unit. Random sequential administration of i NO(20 ppm) or nebulized epoprostenol(10 μg/mL) was done in all patients. Thereafter, inhaled milrinone(1 mg/mL) alone followed by inhaled milrinone in association with inhaled nitric oxide(iN O) was administered. A jet nebulization device synchronized with the mechanical ventilation was use to administrate the epoprostenol and the milrinone. Hemodynamic measurements and partial pressure of arterial oxygen(PaO_2) were recorded before and after each inhaled therapyadministration.RESULTS The majority of ARDS were of pulmonary cause(n = 13) and pneumonia(n = 7) was the leading underlying initial disease. Other pulmonary causes of ARDS were: Post cardiopulmonary bypass(n = 2), smoke inhalation injury(n = 1), thoracic trauma and pulmonary contusions(n = 2) and aspiration(n = 1). Two patients had an extra pulmonary cause of ARDS: A polytrauma patient and an intra-abdominal abscess Inhaled nitric oxide, epoprostenol, inhaled milrinone and the combination of inhaled milrinone and i NO had no impact on systemic hemodynamics. No significant adverse events related to study medications were observed. The median increase of PaO 2 from baseline was 8.8 mmH g [interquartile range(IQR) = 16.3], 6.0 mm Hg(IQR = 18.4), 6 mm Hg(IQR = 15.8) and 9.2 mm Hg(IQR = 20.2) respectively with i NO, epoprostenol, inhaled milrinone, and i NO added to milrinone. Only i NO and the combination of inhaled milrinone and i NO had a statistically significant effect on PaO 2. CONCLUSION When comparing the effects of inhaled NO, milrinone and epoprostenol, only NO significantly improved oxygenation. Inhaled milrinone appeared safe but failed to improve oxygenation in ARDS. | Martin Albert Daniel Corsilli David R Williamson Marc Brosseau Patrick Bellemare Stéphane Delisle Anne QN Nguyen France Varin | 2017 | World Journal of Critical Care Medicine2017，6，1： | 4 |
| 2 | The CONSTANS gene of arabidopsis promotes flowering and encodes a protein showing similarities to zinc finger transcription factors显示文摘 | Joanna Putterill Frances Robson Karen Lee Rüdiger Simon George Coupland | 1995 | Cell1995，，6： | 2 |
| 3 | Influence of Coal Nature and Structure on Ash Size Formation Characteristic and Related Pollutant Emissions During CFB Combustion显示文摘The size distribution of coal particles in a Circulating Fluidized Bed (CFB) boiler plays a crucial role in the complicated combustion, heat exchange and pollutant emissions in such a plat. Therefore, it is fundamental to study the different factors having influence on the size distribution of coal particles. Above all, the coal itself and in particular, the coal combination phenomenon is a very influent factor. In the frame of this work, the coal nature (elementary composition) and coal internal structure (mineral components) are studied in detail. At this intermediary stage, experiments on three typical Chinese coals on a l.5 MWt CFBC pilot plant have been made. Some primary fragmentation tests have also been made in a small lab scale fluidized bed reactor. The results from the hot pilot test show i) the variation of coal ash distributions and other CFB performance data due to the cyclone and the coal characteristics and ii) the variation of desulfurization efficiency with limestone. Whereas the bench scale primary fragmentation test, likely linked to the caking propriety of a coal, does not seem to change considerably the char size distribution. | Min QIAN Arnaud BOELLE Philippe JAUD ( Electricite de France Division R&D, 6 quai Watier B.P.49 78401 Chatou, France ) Yongjie NA Qinggang LU Shaolin BAO ding CUI Weihong JIAO Huanming ZHAO (Institute of Engineering Thermophysics, Chinese Academ | 2000 | Journal of Thermal Science2000，9，3： | 2 |
| 4 | Vascular events after spinal cord injury: contribution to secondary pathogenesis显示文摘 | Angelika E M Martin R W Frances D | 2000 | Phys Ther2000，80，7： | 1 |
| 5 | Friendship within entrepreneurial teams and its association with team and venture performance显示文摘 | Deborah H Frances and William R Sandberg | 2000 | Entrepreneurship Theory and Practice2000，25，2： | 1 |
| 6 | Electrical and luminescence properties of (CdZn)Te single crystals prepared by the vertical gradient freezing method 显示文摘 | HOSCHL P IVANOV Y M BELAS E FRANC J RILL R G HLIDEK P MORAVEC P ZVARA M SITTER H TOTH A L | 1998 | J Cryst Growth1998，，： | 1 |
| 7 | Mental ac- counting and changes in price: the frame depend- ence of reference dependence显示文摘 | Heath T B Chatterjee S France K R | 1995 | Journal of Con- sumer Research1995，22，1： | 1 |
| 8 | Assumptions underlying agile software-development processes 显示文摘 | Turk D France R Rumpe B | 2005 | Journal of Database Management2005，16，4： | 1 |
| 9 | Tumour necrosis factor α: a potential target for the therapy of solid tumours显示文摘 | Peter W Szlosarek Frances R Balkwill | 2003 | Lancet Oncology2003，，9： | 1 |
| 10 | Benthic-pelagic coupling and postdepositional processes as revealed by the distribution of opal in sediments:The case of the Ríade Vigo (NW Iberian Peninsula)显示文摘 | Bernardez P Frances G Prego R | | 0，，： | 1 |
| 11 | Central serous papillopathy by optic nerve head drusen显示文摘 | Suelyes AM Franc(e)s-Munoz E Gallego-Pinazo R | | 0，，： | 1 |
| 12 | Historical changes inlevels of organic pollutants in sediment cores from brno reser-voir,czech republic显示文摘 | Franc U E Sehwarzbauer J Lana R et a1 | 2009 | Water Air Soil Pollution2009，14，： | 1 |
| 13 | Opal content in the Ria de Vigo and Galician continental shelf:biogenic silica in the muddy fraction as an accurate paleoproductivity proxy显示文摘 | Bernardez P Prego R Frances G | | 0，，10： | 1 |
| 14 | Aspect-oriented approach to early design modeling 显示文摘 | France R Ray I Georg G | 2004 | IEEE Software2004，151，2： | 1 |
| 15 | A UML-based pattern specification technlque显示文摘 | France R B Kim D K Ghosh S | 2004 | IEEE Transactions on Software Engineering2004，30，3： | 1 |
| 16 | Changes in lactate-producing and lactate-utilizing bacteria in relation to pH in the rumen of sheep during stepwise adaption to a high-concentrate diet 显示文摘 | Mackie R I Frances M Gilchrist C | 1979 | App Environ Microbio1979，38，3： | 1 |
| 17 | The use fraeral techniques for flow regime identification 显示文摘 | FRANCE F ACIKGOZ M LAHEY R T | 1991 | Int J Multiphase Flow1991，17，4： | 1 |
| 18 | An asse-ssment of a microcolumn chromatographic method for the measurement of haemoglobin A1显示文摘 | Baumgart R France MW UaConaill D | 1980 | Ann Clin Biochem1980，17，2： | 1 |
| 19 | Impact of maternal influenza vaccination during pregnancy on the incidence of acute respiratory illness visits among infants显示文摘 | France EK Smith-Ray R McClure D | 2006 | Arch Pediatr Adolese Med2006，160，12： | 1 |
| 20 | Historical changes in levels of organic pollutants in sediment cores from Bino Reservoir,Czech Republic显示文摘 | Franc U E Schwarzbauer J Lana R | 2009 | Water Air Soil Pollution2009，14，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员