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| 1 | Right ventricular septal pacing: Safety and efficacy in a long term follow up显示文摘AIM: To evaluate the safety and efficacy of the permanent high interventricular septal pacing in a long term follow up, as alternative to right ventricular apical pacing. METHODS: We retrospectively evaluated:(1) 244 patients(74 ± 8 years; 169 men, 75 women) implanted with a single(132 pts) or dual chamber(112 pts) pacemaker(PM) with ventricular screw-in lead placed at the right ventricular high septal parahisian site(SEPTAL pacing);(2) 22 patients with permanent pacemaker and low percentage of pacing(< 20%)(NO pacing);(3) 33 patients with high percentage(> 80%) right ventricular apical pacing(RVA). All patients had a narrow spontaneous QRS(101 ± 14 ms). We evaluated New York Heart Association(NYHA) class, quality of life(Qo L), 6 min walking test(6MWT) and left ventricular function(end-diastolic volume, LV-EDV; end-systolic volume, LVESV; ejection fraction, LV-EF) with 2D-echocardiography. RESULTS: Pacing parameters were stable duringfollow up(21 mo/patient). In SEPTAL pacing group we observed an improvement in NYHA class, Qo L score and 6MWT. While LV-EDV didn't significantly increase(104 ± 40 m L vs 100 ± 37 m L; P = 0.35), LV-ESV slightly increased(55 ± 31 m L vs 49 ± 27 m L; P = 0.05) and LV-EF slightly decreased(49% ± 11% vs 53% ± 11%; P = 0.001) but never falling < 45%. In the RVA pacing control group we observed a worsening of NYHA class and an important reduction of LV-EF(from 56% ± 6% to 43% ± 9%, P < 0.0001).CONCLUSION: Right ventricular permanent high septal pacing is safe and effective in a long term follow up evaluation; it could be a good alternative to the conventional RVA pacing in order to avoid its deleterious effects. | Eraldo Occhetta Gianluca Quirino Lara Baduena Rosaria Nappo Chiara Cavallino Emanuela Facchini Paolo Pistelli Andrea Magnani Miriam Bortnik Gabriella Francalacci Gabriele Dell’Era Laura Plebani Paolo Marino | 2015 | World Journal of Cardiology2015，7，8： | 5 |
| 2 | Classification of European mtDNA from an analysis of three European poplations 显示文摘 | Torroni A Huoponen K Francalacci P | 1996 | Genet Soc Amer1996，144，： | 1 |
| 3 | Classification of European mtDNA from an analysis of three European poplations显示文摘 | Torroni A Huoponen K Francalacci P | 1996 | Genet Soc Amer1996，144，4： | 1 |
| 4 | The effect of neoadjuvant chemotherapy on hormone receptor status,HER2/neu and prolactin in breast cancer显示文摘 | Pedrini JL Francalacci Savaris R Casales Schorr M | | 0，，06： | 1 |
| 5 | Ancestral European roots of Helicobacter pylori in India显示文摘 | DEVI S M AHMED I FRANCALACCI P | 2007 | BMC Genomics2007，8，1： | 1 |
| 6 | Classification of European mtDNAs from analysis of three European populations显示文摘 | Tortoni A Huoponen K Francalacci P | 1996 | Genetics1996，144，4： | 1 |
| 7 | Peopling of three Mediterranean islands (Corsica,Sardinia, and Sicily) inferred by Y-chromosome biallelic variability显示文摘 | Francalacci P Morelli L Underhill PA | 2003 | Am J Phys Anthropol2003，121，3： | 1 |
| 8 | DNA recovery from ancient tissues: problems and perspectives显示文摘 | P. Francalacci | | Human Evolution0，，： | 1 |
| 9 | Classification of European mtDNAs from an analysis of three European populations显示文摘 | Torroni A Huoponen K Francalacci P | 1996 | Genetics1996，144，： | 1 |
| 10 | Prevention of Ventricular Desynchronization by Permanent Para-Hisian Pacing After Atrioventricular Node Ablation in Chronic Atrial Fibrillation显示文摘 | Eraldo Occhetta Miriam Bortnik Andrea Magnani Gabriella Francalacci Cristina Piccinino Laura Plebani Paolo Marino | 2006 | Journal of the American College of Cardiology2006，，10： | 1 |
| 11 | Classification of European mtDNAs from an analysis of three European populations显示文摘 | Torroni A Huoponen K Francalacci P | 1996 | Genetics1996，144，： | 1 |
| 12 | Prevention of Ventricular Desynchronization by Permanent Para-Hisian Pacing After Atrioventricular Node Ablation in Chronic Atrial Fibrillation显示文摘 | Eraldo Occhetta Miriam Bortnik Andrea Magnani Gabriella Francalacci Cristina Piccinino Laura Plebani Paolo Marino | 2006 | Journal of the American College of Cardiology2006，，10： | 1 |
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