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| 1 | What do the recent American Heart Association/American College of Cardiology Foundation Clinical Practice Guidelines tell us about the evolving management of coronary heart disease in older adults?显示文摘Biological aging predisposes older adults to increased cardiovascular disease (CHD) and greater disease complexity. Given the high age-related prevalence of CHDand age-related compounding factors, the recently updatedAmerican HeartAssociation/American College of Cardiology Foundation CHD-related guidelines increased their focus on older patients. These guidelines are predominately evidence-based (using data from quality randomized clinical trials) and are organized to delineate medications and procedures that best treat particular cardiovascular diseases.While such rationale and thought work well in young and middle aged adults, they become problematic in patientswho are very old. Data pertaining to adults aged ≥80 are virtually absent from most randomized clinical trials, and even in the instances when very old patients were included, eligibility criteria typically excluded candidates with co-morbidities and complexities of customary CHD patients. While medications and interventions yielding benefit in clinical trials should theoretically produce the greatest benefits for patients with high intrinsic risk, age-related cardiovascular complexities also increase iatrogenic risks. Navigating between the potential for high benefit and high risk in “evidence-based”cardiovascular management remains a key Geriatric Cardiology challenge. In this review we consider the expanded Geriatric Cardiology content of current guidelines, acknowledging both the progress that has been made, as well as the work that still needs to be accomplished to truly address the patient-centered priorities of older CHDpatients. | Daniel Forman Nanette K Wenger | 2013 | Journal of Geriatric Cardiology2013，10，2： | 3 |
| 2 | A diet containing glycine improves survival in endotoxin shock in the rat显示文摘 | Iimuro Y Forman DT | 1996 | Am J Physiol1996，271，1： | 1 |
| 3 | An exaggerated hypertensive response to glycopyrrolate therapy for bradycardia associated with high-dose dexmedetomidine 显示文摘 | Mason K P Zgleszewski S Forman R E | 2009 | AnesthAnalg2009，108，3： | 1 |
| 4 | Aggregating individual judgments and priorities with the analytic hierarchy process 显示文摘 | FORMAN E PNEUMATI K | 1998 | European JOurnal of Operational Research1998，108，： | 1 |
| 5 | Nature conserved in changing landscapes with and without spatial planning显示文摘 | Forman R T S K Collinge | 1997 | Landscape and Urban Planning1997，37，12： | 1 |
| 6 | 2013 AHA老年动脉粥样硬化性心血管疾病患者的二级预防科学声明显示文摘自2002年首次提出老年心血管疾病二级预防科学声明以来,更多的成年人处于老龄化阶段,每年花费于动脉粥样硬化性心血管疾病(ASCVD)的费用将剧增。因此,对老年ASCVD人群,有效的二级预防措施极其重要。 | Fleg JL Forman DE Berra K 刘春霞 | 2014 | 心血管病学进展2014，35，3： | 1 |
| 7 | Integral Nursing:an emerging framework for engaging the evolution of the profession显示文摘 | Forman J Megel ME | 2003 | Nurs Outlook2003，51，3： | 1 |
| 8 | Endogenous bile acids are ligands for the nuclear receptor FXR/BAR显示文摘 | Wang H Chen J Hollister K Sowers LC Forman BM | 1999 | Mol Cell1999，3，： | 1 |
| 9 | Expression of human immunodeficiency virus type 1 Gag protein precursor and envelope proteins from a vesicular stomatitis virus recombinant: high-level production of virus-like particles containing HIV envelope 显示文摘 | Haglund K Forman J Krausslich H G | 2000 | Virology2000，268，： | 1 |
| 10 | Effect of vitamin D supple- mentation on blood pressure in blaeks显示文摘 | Forman JP Scott JB Ng K | 2013 | Hypertension2013，61，4： | 1 |
| 11 | Adenosine attenuates reperfusion injury following regional myocardial ischaemia 显示文摘 | Forman M B Velasco C E Jackson E K | 1993 | Cardiovasc Res1993，27，1： | 1 |
| 12 | Purpura Fulminans:Recognition,Diagnosis and Management显示文摘 | Chalmers E Cooper P Forman K | 2011 | Arch Dis Child2011，96，11： | 1 |
| 13 | Scale - Dependent Proximity of Wildlife Habitat in a Spatially - Neutral Bayesian Model 显示文摘 | Milne B T Johnston K M Forman R T T | 1989 | Landscape Ecology1989，2，2： | 1 |
| 14 | Purpura fulminans: recognition, diagnosis and management 显示文摘 | Chalmers E Cooper P Forman K | 2011 | e ADC2011，96，11： | 1 |
| 15 | A diet containing glycine improves survival in endotoxin shock in the rat 显示文摘 | Ikejima K Iimuro Y Forman DJ | 1996 | Am J Physiol1996，271，11： | 1 |
| 16 | Aggregating individual judgments and priories with the analytic hierarchy process显示文摘 | Forman E Peniwati K | 1998 | European Journal of Operational Research1998，108，： | 1 |
| 17 | Unique response pathways are established by allosteric interactions among nuclear hormone receptors显示文摘 | Forman BM Umesono K Chen J | 1995 | Cell1995，81，： | 1 |
| 18 | Karyotypic analysis predicts outcome of preremission and postremission therapy in adult acute myeloid leukemia:a Southwest Oncology Group/Eastern Cooperative Oncology Group Study显示文摘 | Slovak ML Kopecky K J Cassileth PA Harrington DH Theil KS Mohamed A Paietta E Willman CL Head DR Rowe JM Forman SJ Appelbaum FR | 2000 | Blood2000，96，13： | 1 |
| 19 | Aggregating individual judgments and priorities with the analytic hierarchy process显示文摘 | Forman E Peniwati K | 1998 | European Journal of Operational Research1998，108，： | 1 |
| 20 | Uique response pathways are established by allosteric interactions among nuclear hormone receptor显示文摘 | Forman BM Umesono K Chen J | 1995 | Cell1995，81，： | 1 |
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