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| 1 | Extrahepatic complications to cirrhosis and portal hypertension: Haemodynamic and homeostatic aspects显示文摘In addition to complications relating to the liver, patients with cirrhosis and portal hypertension develop extrahepatic functional disturbances of multiple organ systems. This can be considered a multiple organ failure that involves the heart, lungs, kidneys, the immune systems, and other organ systems. Progressive fibrosis of the liver and subsequent metabolic impairment leads to a systemic and splanchnic arteriolar vasodilatation. This affects both the haemodynamic and functional homeostasis of many organs and largely determines the course of the disease. With the progression of the disease, the circulation becomes hyperdynamic with cardiac, pulmonary as well as renal consequences for dysfunction and reduced survival. Infections and a changed cardiac function known as cirrhotic cardiomyopathy may be involved in further aggravation of other complications such as renal failure precipitatingthe hepatorenal syndrome.Patients with end-stage liver disease and related complications as for example the hepatopulmonary syndrome can only radically be treated by liver transplantation.As a bridge to this treatment,knowledge on the mechanisms of the pathophysiology of complications is essential for the choice of vasoactive drugs,antibiotics,drugs with specific effects on fibrogenesis and inflammation,and drugs that target specific receptors. | S?ren M?ller Jens H Henriksen Flemming Bendtsen | 2014 | World Journal of Gastroenterology2014，20，42： | 14 |
| 2 | 六氯化苯对汤氏纺锤水蚤毒性影响的比较研究显示文摘本文通过1987年6月在丹麦国家环保局海洋污染实验室进行的六氯化苯(γ-HCH)对桡足类汤氏纺锤水蚤(Acartia tonsa)的急性、亚急性和生命周期试验,评价了六氯化苯对汤氏纺锤水蚤的毒性。试验结果表明,γ-HCH对汤氏纺锤水蚤的96h LC_(50)为17μg/L。当,γ-HCH浓度为3μg/L时,产卵量明显受到影响。在生命周期试验中,当γ-HCH浓度为10μg/L时,从无节幼体Ⅵ期到成体,汤氏纺锤水蚤的生长会受到明显影响,而对雌性成体的半数影响浓度(EC_(50))为0.8μg/L。通过对试验方法和结果的比较分析文中认为,汤氏纺锤水蚤的生命周期试验,敏感性高、操作简便、费用相对较低,将会是化学物质危害性评价中一个很有用的方法。 | 陈民山 Flemming Mhlenberg | 1991 | 海洋与湖沼1991，22，3： | 2 |
| 3 | No difference in portal and hepatic venous bacterial DNA in patients with cirrhosis undergoing transjugular intrahepatic portosystemic shunt insertion显示文摘 | Christian Mortensen Stine Karlsen Henning Gr?nb?k Dennis T. Nielsen Susanne Frevert Jens O. Clemmesen S?ren M?ller J?rgen S. Jensen Flemming Bendtsen | 2013 | Liver Int2013，，9： | 2 |
| 4 | Partial Cross Sections and Photoelectron Angular Distributions in the Region of 4s→5p and 5s→6p Resonances in Krypton and Xenon显示文摘 | Wu J Z Caldwell C D | 1991 | Phys Rev1991，44，： | 1 |
| 5 | Application of fluorescenfly labelled lectins for the visualization and biochemical characterization of polysaccharides in biofilms of Pseudomonas aeruginosa 显示文摘 | STRATHMAN M WINGENDER J FLEMMING H C | 2002 | J Microbiol Meth2002，50，3： | 1 |
| 6 | From the archives of the AFIP : benign musculoskeletal lipomatous lesions (Review) 显示文摘 | Murphey M D Carroll J F Flemming D J | 2004 | Radiographics2004，24，5： | 1 |
| 7 | Behavior of metal and alloys in the semi-solid state 显示文摘 | Flemming M C | 1991 | Metal Trans1991，22，： | 1 |
| 8 | Application of fluorescently labelled lectins for the visualization and biochemical characterization of polysaccharides in biofilms of Pseudomonas aeruginosa显示文摘 | Strathmann M Wingender J Flemming H C | 2002 | J Microbiol Methods2002，50，3： | 1 |
| 9 | Multiobjective optimization and multiple constraint handling with evolutionary algorithms,part II:application example显示文摘 | Fonseca C M Flemming P J | 1998 | Systems Man and Cybernetics1998，28，： | 1 |
| 10 | Enchon- droma versus chondrosarcoma in the appendicular skeleton: diffe- rentiating features 显示文摘 | MURPHEY M D FLEMMING D J BOYEA S R | 1998 | Radiographics1998，18，5： | 1 |
| 11 | Multiobjective optimisation and multiple constraint handling with evolutionary algorithms-part Ⅰ:a unified formulation and part Ⅱ:application example显示文摘 | FONESCA C M FLEMMING P J | 1998 | IEEE Trans on Systems Man and Cybernetics Part A:Systems and Humans1998，28，1： | 1 |
| 12 | Detection of heavy metals in bacterial biofilms and microbial flocs with the fluorescent complexing agent Newport Green显示文摘 | S Wuertz E Müller R Spaeth P Pfleiderer H-C Flemming | 2000 | Journal of Industrial Microbiology & Biotechnology2000，，2： | 1 |
| 13 | Expression level, tissue distribution pattern, and prognostic impact of vascular endothelial growth factors VEGF and VEGF- C and their receptors Fit-l, KDR, and Flt-4 in different subtypes of non-Hodgkin lymphomas 显示文摘 | Judit M Flemming B Bendix K | 2009 | Leuk Lymph2009，50，10： | 1 |
| 14 | Behavior of metal and alloys in the semi-solid state显示文摘 | FLEMMING M C | 1991 | Metal Trans1991，22，： | 1 |
| 15 | Behavior of metal and alloys in the semi-solid state显示文摘 | FLEMMINGS M C | 1991 | Metallurgical Transactions B1991，22，3： | 1 |
| 16 | Carvedilol or propranolol in portal hypertension? A randomized comparison显示文摘 | Lise Hobolth S?ren M?ller Henning Gr?nb?k Klaus Roelsgaard Flemming Bendtsen Erik Feldager Hansen | 2012 | Scandinavian Journal of Gastroenterology2012，，4： | 1 |
| 17 | Mannose binding lectin deficiency revisited显示文摘 | Peter G Flemming L Hans O M | 2003 | Molecular Immunology2003，1，： | 1 |
| 18 | Simultaneous extraction of te- tracycline, macrolide and sulfonamide antibiotics from agricultural soils using pressurised liquid extraction, followed by solid-phase ex- traction and liquid chromatography tandem mass spectrometry显示文摘 | Anne M J Bent H S Flemming I | 2004 | Jour- nal of Chromatography A2004，1038，12： | 1 |
| 19 | Benign musculoskeletal lipomatous lesions显示文摘 | Murphey M D Carroll J F Flemming D J | 2004 | RadioGraphic2004，24，： | 1 |
| 20 | Organotin - induced hemolysis, shape transformation and intramembranous aggregates in human erythrocytes 显示文摘 | GRAY B H PORVAZNIK M FLEMMING C | 1987 | Cell Biol Toxicol1987，3，1： | 1 |
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