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| 1 | Uppermost Permian reefs in Skyros(Greece) and Sichuan (China):Implications for the Late Permian extinction event显示文摘 | Flüegel E Reinhardt J | 1989 | Palaios1989，4，6： | 1 |
| 2 | Acute and chronic presentation of intestinal nonrotation in adults显示文摘 | Markus Flüe M.D. Urs Herzog M.D. Christoph Ackermann M.D. Peter Tondelli M.D. Felix Harder M.D | 1994 | Diseases of the Colon & Rectum1994，，2： | 1 |
| 3 | An atomic force microscopy study on the effect of bleaching agents on enamel surface显示文摘 | Hegedüs C Bistey T Flóra-Nagy E | 1999 | Dentistry1999，27，07： | 1 |
| 4 | How accurate is endorectal ultrasound in the preoperative staging of rectal cancer ?显示文摘 | Herzog U von Flüe M Tondelli P | 1993 | Dis Colon Rectum1993，36，2： | 1 |
| 5 | Effects of tiotropium onlung hyperinflation,dyspnoea and exercise tolerance in COPD显示文摘 | O’Donnell D E Flüge T Gerken F | 2004 | EurRespir J2004，23，6： | 1 |
| 6 | Is routine MR cholangiopancreatography (MRCP) justified prior to cholecystectomy?显示文摘 | C. A. Nebiker S. A. Baierlein S. Beck M. Flüe C. Ackermann R. Peterli | 2009 | Langenbeck’s Archives of Surgery2009，，6： | 1 |
| 7 | Transanal endoscopic microsurgical excision of rectal tumors: Indications and results显示文摘 | Nicolas Demartines Marcus O. Flüe Felix H. Harder | 2001 | World Journal of Surgery2001，，7： | 1 |
| 8 | Transanal endoscopic microsurgical excision of rectal tumors: Indications and results显示文摘 | Nicolas Demartines M.D. Marcus O. Flüe M.D. Felix H. Harder M.D | 2001 | World Journal of Surgery2001，，7： | 1 |
| 9 | An atomic force microscopy study on the effect of bleaching agents on enamel surface显示文摘 | Hegedüs C Bistey T Flóra-Nagy E | 1999 | J Dent1999，27，7： | 1 |
| 10 | How accurate is endorectal ultrasound in the preoperative staging of rectal cancer?显示文摘 | Herzog U von Flüe M Tondelli P | 1993 | Dis Colon Rectum1993，36，2： | 1 |
| 11 | Ultrastructure of the trabecular meshwork in untreated cases of primary open-angle glaucoma (POAG) 显示文摘 | ROHEN JW LüITJEN-DRECOLL E FLüGEL C | 1993 | Exp Eye Res1993，56，6： | 1 |
| 12 | Abdominal Actinomycosis: a Rare Complication after Laparoscopic Gastric Bypass显示文摘 | Sammy A. Baierlein Anja Wistop Christian Looser Thomas Peters Hans-Martin Riehle Markus Flüe Ralph Peterli | 2007 | Obesity Surgery2007，，8： | 1 |
| 13 | Long-Term Results After Stapled Hemorrhoidopexy: High Patient Satisfaction Despite Frequent Postoperative Symptoms显示文摘 | P. Fueglistaler M. O. Guenin I. Montali B. Kern R. Peterli M. Flüe C. Ackermann | 2006 | Diseases of the Colon & Rectum2006，，2： | 1 |
| 14 | Clinical and histopathological correlations of fecal calprotectin release in colorectal carcinoma显示文摘AIM:To determine calprotectin release before and after colorectal cancer operation and compare it to tumor and histopathological parameters.METHODS:The study was performed on patients with diagnosed colorectal cancer admitted for operation.Calprotectin was measured in a single stool sample before and three months after the operation using an enzymelinked immunosorbent assay(ELISA).Calprotectin levels greater than or equal to 50μg/g were considered positive.The compliance for collecting stool samples was assessed and the value of calprotectin was correlated to tumor and histopathological parameters of intra-and peri-tumoral inflammation.Surgical specimens were fixed in neutral buffered formalin and stained with hematoxylin and eosin.Staging was performed according to the Dukes classification system and the 7th edition tumor node metastasis classification system.Intra-and peri-tumoral inflammation was graded according to the Klintrup criteria.Immunohistochemical quantification was performed for MPO,CD45R0,TIA-1,CD3,CD4,CD8,CD57,and granzyme B.Statistical significance was measured using Wilcoxon signed rank test,Kruskal Wallis test and Spearman’s rank correlation coefficient as appropriate.RESULTS:Between March 2009 and May 2011,80 patients with colorectal cancer(46 men and 34 women,with mean age of 71±11.7 years old)were enrolled in the study.Twenty-six patients had rectal carcinoma,29 had left-side tumors,23 had right-side tumors,and2 had bilateral carcinoma.In total,71.2%of the patients had increased levels of calprotectin before the operation(median 205μg/g,range 50-2405μg/g)and experienced a significant decrease three months after the operation(46μg/g,range 10-384μg/g,P<0001).The compliance for collecting stool samples was 89.5%.Patients with T3 and T4 tumors had significantly higher values than those with T1 and T2 cancers(P=0.022).For all other tumor parameters(N,M,G,L,V,Pn)and location,no significant difference in calprotectin concentration was found.Furthermore,the calprotectin levels and histological grading of both peri-and intra-tumoral inflammation was not correlated.Additional testing with specific markers for lymphocytes and neutrophils also revealed no statistically significant correlation.CONCLUSION:Fecal calprotectin decreases significantly after colorectal cancer operation.Its value depends exclusively on the individual T-stage,but not on other tumor or histopathological parameters. | Frank Serge Lehmann Francesca Trapani Ida Fueglistaler Luigi Maria Terracciano Markus von Flüe Gieri Cathomas Andreas Zettl Pascal Benkert Daniel Oertli Christoph Beglinger | 2014 | World Journal of Gastroenterology2014，20，17： | 6 |
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