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| 1 | Biomarkers in Barrett's esophagus and esophageal adenocarcinoma:Predictors of progression and prognosis显示文摘Barrett’s esophagus is a well-known premalignant lesion of the lower esophagus that is characterized by intestinal metaplasia of the squamous epithelium. It is clinically important due to the increased risk (0.5% per annum) of progression to esophageal adenocarcinoma (EA), which has a poor outcome unless diagnosed early. The current clinical management of Barrett’s esophagus is hampered by the lack of accurate predictors of progression. In addition, when patients develop EA, the current staging modalities are limited in stratifying patients into different prognostic groups in order to guide the optimal therapy for an individual patient. Biomarkers have the potential to improve radically the clinical management of patients with Barrett’s esophagus and EA but have not yet entered mainstream clinical practice. This is in contrast to other cancers like breast and prostate for which biomarkers are utilized routinely to inform clinical decisions. This review aims to highlight the most promising predictive and prognostic biomarkers in Barrett’s esophagus and EA and to discuss what is required to move the field forward towards clinical application. | Chin-Ann J Ong Pierre Lao-Sirieix Rebecca C Fitzgerald | 2010 | World Journal of Gastroenterology2010，16，45： | 6 |
| 2 | 非甾体抗炎药应用中,环氧合酶2、不对称二甲基精氨酸与心血管危害的关系显示文摘已有大规模、安慰剂对照试验确定了非甾体类抗炎药(nonsteroidal anti—inflammatory drugs,NSAIDs)具有心血管危害性:这归因于环氧合酶2(cyclooxygenase,COX-2)的心脏保护产物受到抑制,尤其是前列环素(prostacyclin,PG12)。NSAID降低心脏保护作用的另一种机制可能是通过增强肾脏中甲基精氨酸的形成来限制一氧化氮在整个脉管系统中的作用。 | Ricciotti E Castro C Tang SY Briggs WTE West JA Malik D Rhoades SD Meng H Li X Lahens NF Sparks JA Karlson EW Weljie AM Griffin JL FitzGerald GA6 刘青 叶鹏 | 2018 | 中华高血压杂志2018，26，9： | 3 |
| 3 | Evidence for a disease-resistance pathway in rice similar to the NPR1-mediated signaling pathway in Arabidopsis显示文摘 | Chern M S Fitzgerald H A Yadav R C | 2001 | Plant J2001，27，2： | 2 |
| 4 | 查看详情显示文摘 | Beeson J C Fitzgerald L J Gullucci J C | | 0，，： | 2 |
| 5 | Supply chain methodology显示文摘 | Harland C Williams D Fitzgerald L | 1993 | Human Systems Management1993，12，： | 1 |
| 6 | The coxibs,selective inhibitors of cyclooxygenase-2显示文摘 | FITZGERALD GA PATRONO C | 2001 | N Engl J Med2001，345，6： | 1 |
| 7 | Donor impurity band exchange in dilute ferromagnetic oxides显示文摘 | Coey J M D Venkatesan M Fitzgerald C B | 2005 | Nat Mater2005，4，： | 1 |
| 8 | Platelet-active drugs : the rela- tionships among dose, effectiveness, and side effects:the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy 显示文摘 | Patrono C Coller B FitzGerald GA | 2004 | Chest2004，12，6： | 1 |
| 9 | Analysis of hem odynam ic and ventlatory effects of laparoscopic cholecy-stomy显示文摘 | Wittgen C M Andrus J Fitzgerald S D | 1991 | Arch Surg1991，123，8： | 1 |
| 10 | Respiratory disease associated with solid biomass fuel exposure in rural women and children:systematic re- view and meta-analysis显示文摘 | Po JT Fitzgerald JM Carlsten C | 2011 | Thorax2011，66，： | 1 |
| 11 | Looking Beyond the Terrestrial:The Potential of Seaweed Derived Bioactives to Treat Non-Communicable Diseases显示文摘 | Collins KG Fitzgerald GF Stanton C | 2016 | Mar Drugs2016，14，3： | 1 |
| 12 | Intratympanic Steroids for Idiopathic Sudden Sensorineural Hearing Loss显示文摘 | Fitzgerald D C | 2007 | Ann Otol Rhinol Laryngol2007，116，4： | 1 |
| 13 | An analysis of success factors and benefits of Partnering in construction显示文摘 | BLACK C AKINTOYE A FITZGERALD E | 2000 | International Journal of Project Management2000，，18： | 1 |
| 14 | Platelet-Ac- tiveDrugs: the relationships among dose, efectiveness and sideeffects: the Seventh ACCP Conference on An- tithrombotie and Thromholytic Therapy 显示文摘 | Patrono C Coller B FitzGerald GA | 2011 | Chest2011，126，3： | 1 |
| 15 | Ovarian activity in women taking an oral contraceptive containing 20 microg ethinyl estra- diol and 150 microg desogestreh Effects of low estrogen doses during the hormone free interval显示文摘 | Killick S R Fitzgerald C Davis A | 1998 | American Journal of Obstet- rics and Gynecology1998，179，1： | 1 |
| 16 | Localization of Neogenin protein during morphogenesis in the mouse emrbyo显示文摘 | Fitzgerald D P Seaman C Cooper H M | 2006 | Dev Dyn2006，235，6： | 1 |
| 17 | The efficacy of octreotide in the therapy of severe nonproliferative and early proliferative diabetic retinopathy:a randomized controlled study显示文摘 | Grant MB Mames RN Fitzgerald C | 2000 | Diabetes Care2000，23，： | 1 |
| 18 | Pelvic support, pel- vic symptoms, and patient satisfaction after colpocleisis显示文摘 | Fitzgerald M P Richter H E Bradley C S | 2008 | Int Uro- gynecol J Pelvic Floor Dys/unct2008，19，12： | 1 |
| 19 | Molecular mechanisms involved in in- flammasome activation 显示文摘 | Bryant C and Fitzgerald K A | 2009 | Trends Cell Biol2009，19，： | 1 |
| 20 | Com- mon severe infections in chronic granulomatous disease 显示文摘 | Marciano B E Spalding C Fitzgerald A | 2014 | Clin Infect Dis2014，，： | 1 |
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