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| 1 | Bone marrow mesenchymal stem cell therapy in ischemic stroke: mechanisms of action and treatment optimization strategies显示文摘Animal and clinical studies have confirmed the therapeutic effect of bone marrow mesenchymal stem cells on cerebral ischemia, but their mechanisms of action remain poorly understood. Here, we summarize the transplantation approaches, directional migration, differentiation, replacement, neural circuit reconstruction,angiogenesis, neurotrophic factor secretion, apoptosis, immunomodulation, multiple mechanisms of action,and optimization strategies for bone marrow mesenchymal stem cells in the treatment of ischemic stroke.We also explore the safety of bone marrow mesenchymal stem cell transplantation and conclude that bone marrow mesenchymal stem cell transplantation is an important direction for future treatment of cerebral ischemia. Determining the optimal timing and dose for the transplantation are important directions for future research. | Guihong Li Fengbo Yu Ting Lei Haijun Gao Peiwen Li Yuxue Sun Haiyan Huang Qingchun Mu | 2016 | Neural Regeneration Research2016，11，6： | 22 |
| 2 | Intermetallic Compounds in the Banded Structure and Their Effect on Mechanical Properties of Al/Mg Dissimilar Friction Stir Welding Joints显示文摘Dissimilar friction stir welding(FSW) between aluminum and magnesium alloy was performed, using various tool rotational speed(TRS) at a ?xed travel speed, with tool offset to aluminum to investigate the formation of intermetallic compounds(IMCs) in the banded structure(BS) zone and their effect on mechanical properties. Large quantities of IMCs, in the form of alternating bands of particles or lamellae, were found in the BS zone, where drastic material intermixing occurred during FSW. The BS microstructural characters in terms of the morphology of the bands and the quantity and distribution of IMC particles varied with TRS. All welds exhibited brittle fracture mode with their fracture paths propagating mainly in/along the IMCs in the BS. It is shown that these BS microstructural characters have signi?cant effect on the mechanical properties of the joints. Suggestions on tailoring the BS microstructure were proposed for improving the strength of the BS zone and the ?nal mechanical properties of the Al/Mg FSW joints. | Hui Shi Ke Chen Zhiyuan Liang Fengbo Dong Taiwu Yu Xianping Dong Lanting Zhang Aidang Shan | 2017 | Journal of Materials Science & Technology2017，33，4： | 8 |
| 3 | An efficient chemical reduction-induced assembly of Fe_(3)O_(4)@graphene fiber for wire-shaped supercapacitors with ultrahigh volumetric energy density显示文摘Benefiting from high flexibility and weavability,the wire-shaped supercapacitors(SCs)arouse tremendous interests for the applications in wearable/portable electronics.Graphene fiber(GF)is considered as a promising linear electrode for wire-shaped SCs.However,the bottleneck is how to develop the GF-based linear electrode with facile fabrication process while wellmaintaining satisfactory electrochemical performance.Herein,a novel Fe_(3)O_(4)@GF composite linear electrode is proposed via a chemical reduction-induced assembly approach,in which the GO and Fe_(3)O_(4) nanoparticles(NPs)realize the efficient selfassembly owing to the electrostatic and van der Waals interactions,as well as the sufficient reduction of GO during the preparation process.The resultant fiber-shaped architecture shows boosted charge-transfer kinetics,high flexibility and structural integrity.Such Fe_(3)O_(4)@GF linear electrode exhibits excellent electrochemical behaviors including a large volumetric specific capacitance(~250.75 F cm^(−3)),remarkable rate capability and favorable electrochemical kinetics in aqueous electrolyte,superior than previously reported GF-based linear electrodes.For real application,a high-performance wire-shaped SC with excellent flexibility and weavability is fabricated based on such Fe_(3)O_(4)@GF linear electrode and gel electrolyte,demonstrating ultrahigh volumetric energy density(18.8 mWh cm^(−3)),power density(4000 mW cm^(−3))and strong durability(~93.5%retention after 10000 cycles).Prospectively,the fabricated wire-shaped SC can maintain reliable electrochemical behaviors in various deformation states,showing its potentials in future portable and wearable devices. | XIAO Peng SHI MinJie XU Li TAO FengBo LI Yu ZHU HangTian LIU YuTing LI ZhiMin ZHOU YunPeng FENG Wei | 2021 | Science China(Technological Sciences)2021，64，10： | 1 |
| 4 | Network Invulnerability Enhancement Algorithm Based on WSN Closeness Centrality显示文摘Wireless Sensor Network(WSN)is an important part of the Internet of Things(IoT),which are used for information exchange and communication between smart objects.In practical applications,WSN lifecycle can be influenced by the unbalanced distribution of node centrality and excessive energy consumption,etc.In order to overcome these problems,a heterogeneous wireless sensor network model with small world characteristics is constructed to balance the centrality and enhance the invulnerability of the network.Also,a new WSN centrality measurement method and a new invulnerability measurement model are proposed based on the WSN data transmission characteristics.Simulation results show that the life cycle and data transmission volume of the network can be improved with a lower network construction cost,and the invulnerability of the network is effectively enhanced. | Qian Sun Fengbo Yang Xiaoyi Wang Jing Li Jiping Xu Huiyan Zhang Li Wang Jiabin Yu Xiao Peng Ruichao Wang | 2022 | Computers, Materials & Continua2022，，11： | 0 |
| 5 | Optimal Deployment of Heterogeneous Nodes to Enhance Network Invulnerability显示文摘Wireless sensor networks(WSN)can be used in many fields.In wireless sensor networks,sensor nodes transmit data in multi hop mode.The large number of hops required by data transmission will lead to unbalanced energy consumption and large data transmission delay of the whole network,which greatly affects the invulnerability of the network.Therefore,an optimal deployment of heterogeneous nodes(ODHN)algorithm is proposed to enhance the invulnerability of the wireless sensor networks.The algorithm combines the advantages of DEEC(design of distributed energy efficient clustering)clustering algorithm and BAS(beetle antenna search)optimization algorithm to find the globally optimal deployment locations of heterogeneous nodes.Then,establish a shortcut to communicate with sink nodes through heterogeneous nodes.Besides,considering the practical deployment operation,we set the threshold of the mobile location of heterogeneous nodes,which greatly simplifies the deployment difficulty.Simulation results show that compared with traditional routing protocols,the proposed algorithm can make the network load more evenly,and effectively improve energy-utilization and the fault tolerance of the whole network,which can greatly improve the invulnerability of the wireless sensor networks. | Qian Sun Fengbo Yang Xiaoyi Wang Jiping Xu Huiyan Zhang Li Wang Jiabin Yu Xiao Peng Ruichao Wang | 2022 | Computers, Materials & Continua2022，，11： | 0 |
| 6 | Dynamic Viscoelastic Properties of γ Rays Treated Bamboo Strip in Different Temperatures显示文摘The dynamic viscoelastic properties of bamboo were tested by dynamic mechanics analyzer (DMA),and the measurements were done in the temperature range of 40℃ to 300℃at frequencies of 3 Hz.The results showed that with the increase of irradiation dose,the decrease of storage modulus with increasing temperature became more dramatically.The decrease extent of storage modulus was the lowest for non-irradiated bamboo.Two mechanical relaxation processes were observed for all kinds of irradiated bamboo.The a relaxation process in lower temperature range was due to glass transition of hemicellulose and login,while the β relaxation process occurred in higher temperature range was based on glass transition of cellulose.The loss peak strength ofαrelaxation process went up as the irradiation dose increase,while the loss peak strength of β relaxation process became up first and then down,which was caused by the chemical reaction of the chief composition of bamboo. | Sun Fengbo Fei Benhua Jiang Zehui Cheng Haitao Yu Zixuan Chang Xiangzhen | 2012 | Chinese Forestry Science and Technology2012，11，3： | 0 |
| 7 | Continuously released Zn^(2+)in 3D-printed PLGA/β-TCP/Zn scaffolds for bone defect repair by improving osteoinductive and anti-inflammatory properties显示文摘Long-term nonunion of bone defects has always been a major problem in orthopedic treatment.Artificial bone graft materials such as Poly(lactic-co-glycolic acid)/β-tricalcium phosphate(PLGA/β-TCP)scaffolds are expected to solve this problem due to their suitable degradation rate and good osteoconductivity.However,insufficient mechanical properties,lack of osteoinductivity and infections after implanted limit its large-scale clinical application.Hence,we proposed a novel bone repair bioscaffold by adding zinc submicron particles to PLGA/β-TCP using low temperature rapid prototyping 3D printing technology.We first screened the scaffolds with 1 wt%Zn that had good biocompatibility and could stably release a safe dose of zinc ions within 16 weeks to ensure long-term non-toxicity.As designed,the scaffold had a multi-level porous structure of biomimetic cancellous bone,and the Young’s modulus(63.41±1.89 MPa)and compressive strength(2.887±0.025 MPa)of the scaffold were close to those of cancellous bone.In addition,after a series of in vitro and in vivo experiments,the scaffolds proved to have no adverse effects on the viability of BMSCs and promoted their adhesion and osteogenic differentiation,as well as exhibiting higher osteogenic and anti-inflammatory properties than PLGA/β-TCP scaffold without zinc particles.We also found that this osteogenic and anti-inflammatory effect might be related to Wnt/β-catenin,P38 MAPK and NFkB pathways.This study lay a foundation for the follow-up study of bone regeneration mechanism of Zn-containing biomaterials.We envision that this scaffold may become a new strategy for clinical treatment of bone defects. | Chunxu Li Fengbo Sun Jingjing Tian Jiahao Li Haidan Sun Yong Zhang Shigong Guo Yuanhua Lin Xiaodan Sun Yu Zhao | 2023 | Bioactive Materials2023，，6： | 0 |
| 8 | Suspension printing of liquid metal in yield-stress fluid for resilient 3D constructs with electromagnetic functions显示文摘Liquid metal is an ideal conductive material for soft electronics because of its high conductivity and fluidity at room temperature.However,the large surface tension and high mass density of liquid metal make forming three-dimensional(3D)dangling structures a challenging task.Reported here is a suspension printing strategy for direct deposition of galinstan-based liquid metal into 3D dangling structures with high shape fidelity and spatial resolution(~150μm).Acrylamide/nanoclay suspension served as a yieldstress fluid support bath,with selected hydrogen peroxide to immediately oxidize the gallium skin and strengthen the extruded liquid metal,thus continuous liquid metal filaments were deposited successfully.The subsequent photo-curing of acrylamide/nanoclay works as a resilient outer packaging,giving rise to a~500%tensile deformation for liquid metal-hydrogel composite.This suspension printing strategy should broaden the opportunity of using 3D and functional liquid metal constructs for soft yet resilient electromagnetic devices. | Qian Wu Fengbo Zhu Ziliang Wu Yu Xie Jin Qian Jun Yin Huayong Yang | 2022 | npj Flexible Electronics2022，6，1： | 0 |
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