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| 1 | Celecoxib-related gastroduodenal ulcer and cardiovascular events in a randomized trial for gastric cancer prevention显示文摘AIM: To evaluate the long-term risk of gastroduodenal ulcer and cardiovascular events induced by celecoxib in a population-based, randomized, double-blind, placebo-controlled study.METHODS: From 2004 to 2006, a total of 1024 Chinese patients (aged 35 to 64 years) with severe chronic atrophic gastritis, intestinal metaplasia or dysplasia were randomly assigned to receive 200 mg of celecoxib twice daily or placebo in Linqu County (Shandong Province, China), a high-risk area of gastric cancer. All gastroduodenal ulcer and cardiovascular events occurred were recorded and the patients were followed up for 1.5 years after treatment. At the end of the trial, a systematic interview survey about other adverse events was conducted. RESULTS: Gastroduodenal ulcer was detected in 19 of 463 (3.72%) patients who received celecoxib and 17 of 473 (3.31%) patients who received placebo, respectively (odds ratio = 1.13, 95% CI = 0.58-2.19). Cardiovascular (CV) events occurred in 4 patients who received celecoxib and in 5 patients who received placebo, respectively. Compared with those who received placebo, patients who received celecoxib had no signif icant increase in occurrence of CV events (hazard ratio = 0.84, 95% CI = 0.23-3.15). Among the adverse events acquired by interview survey, only the frequency of bloating was signif icantly higher in patients treated with celecoxib than in those treated with placebo. CONCLUSION: Treatment of gastric cancer with celecoxib is not associated with increased risk of gastroduodenal ulcer and cardiovascular events. | Guo-Shuang Feng Jun-Ling Ma Benjamin CY Wong Lian Zhang Wei-Dong Liu Kai-Feng Pan Lin Shen Xiao-Dong Zhang Jie Li Harry HX Xia Ji-You Li Shiu Kum Lam Wei-Cheng You | 2008 | World Journal of Gastroenterology2008，14，28： | 4 |
| 2 | Partitioning regularity of nonionic organic mixtures in organic phase/water system显示文摘The partitioning regularity of nonionic organic mixtures in organic phase/water system is revealed. The equation for calculating the partition coefficients of mixtures (KMD), together with the determination model, is derived from the equilibrium partitioning models (EPMs). Based on these derived equations, the KMD values of 20 mixtures containing halogenated benzenes are obtained. The results show that stronger hydrophobidty of an individual chemical in the mixture results in the stronger hydrophobidty of the mixture and the greater the proportion of this chemical, the stronger the hydrophobidty of the mixture will be. This partitioning regularity is helpful to the study of the toxicity for mixtures and the environmental behavior, such as transfer or accumulation, for mixed organic pollutants. | Lin, ZF Yu, HX Huang, LM Feng, JF Wang, LS | 2001 | Chinese Science Bulletin2001，46，17： | 2 |
| 3 | Cryptococeosis of lumbar verte- bra in a patient with rheumatoid arthritis and seleroderma : ease re- port and literature review 显示文摘 | Zhou HX Ning GZ Feng SQ | 2013 | B MC Infectious Diseases2013，13，： | 1 |
| 4 | Stearic acid/polymethyl metha- crylate composite as form-stable phase change materials for la- tent heat thermal energy storage 显示文摘 | Wang Y Xia TD Feng HX et a/ | 2011 | Renewable Energy2011，36，6： | 1 |
| 5 | Toxicity of concurrent chemoradiotherapy with cetuximab for locoregionally ad- vanced nasopharyngeal carcinoma显示文摘 | Feng HX Guo SP Li GR | 2014 | Med Oncol2014，31，9： | 1 |
| 6 | Brain edema after experimental intracerebral hemorrhage:role of hemoglobin degradation products显示文摘 | Feng PH Guo HX Richard FK | 2002 | Neurosurgery2002，96，： | 1 |
| 7 | Therapeutic effects of adeno- virus-mediated growth and differentiation actor-5 in a mice disc degeneration model induced by annulus needle puncture 显示文摘 | Liang HX Ma SY Feng G etal | 2010 | Spine J2010，10，1： | 1 |
| 8 | Brain edeme after exp-rimental intracerebral hemorrhage:role of hemoglobin degradation products显示文摘 | Guo HX Richard FK | 2002 | Neurosurgery2002，96，： | 1 |
| 9 | Down-regulation of catalase and oxidative modification of protein kinase CK2 lead to the failure of apoptosis repressor with caspase recruitment domain to inhibit cardiomyocyte hypertrophy显示文摘 | Murtaza I Wang HX Feng X | 2008 | J Bioil Chem2008，283，10： | 1 |
| 10 | Down-regulation of catalase and oxidative modification of protein kinase CK2 lead to the failure of apoptosis repressor with caspase recruitment domain to inhibit cardiomyocyte hypertrophy 显示文摘 | Murtaza I Wang HX Feng X | 2008 | J Biol Chem2008，283，10： | 1 |
| 11 | Toxicity of concurrent chemoradio- therapy with cetuximab for locoregionally advanced nasopharyngeal carcinoma 显示文摘 | Feng HX Guo SP Li GR | 2014 | Med Oncol2014，31，9： | 1 |
| 12 | HER2-enriched tumors have the highest risk of local recurrence in Chinese patients treated with breast conservation therapy显示文摘 | Jia WJ Jia HX Feng HY | 2014 | Asian Pac J Cancer Prey2014，15，1： | 1 |
| 13 | Microsurgical treatment of cerebral falx meningioma 显示文摘 | Sun HX Feng LX | 2010 | Henan Journal of Surgery2010，16，4： | 1 |
| 14 | Therapeutic effects of adenovirus - mediated growth and differentiation factor -5 in a mice disc degener- ation model induced by annulus needle puncture 显示文摘 | Liang HX Ma SY Feng G | 2010 | Spine J2010，1，： | 1 |
| 15 | Strategies for maximizing free-radical grafting reaction yields 显示文摘 | HUGH LI HX FENG LF | 2003 | Appl Polym Sei2003，88，7： | 1 |
| 16 | Rate of the activated anionic polymerisation of E-caprolactam onto an isocyanate bearing polypropylene in the melt显示文摘 | HUGH LI HX FENG LF | 2005 | Polymer2005，46，13： | 1 |
| 17 | EFFECTS OF GAS FLOW RATE ON CLARK-TYPE OXYGEN GAS SENSOR显示文摘EFFECTS OF GAS FLOW RATE ON CLARK-TYPE OXYGEN GAS SENSOR￥ShanJunLIU;HanXiSHEN(DepartmentofChemistry,NankaiUniversity,Tianjin,... | Liu, SJ Shen, HX Qiu, YH Wang, H Feng, JX | 1995 | Chinese Chemical Letters1995，6，6： | 0 |
| 18 | GAS FLOW INJECTION DETERMINATION OF NITROGEN DIOXIDE USING GALVANIC COULOMETRIC DETECTOR显示文摘GASFLOWINJECTIONDETERMINATIONOFNITROGENDIOXIDEUSINGGALVANICCOULOMETRICDETECTOR￥ShanJunLIU;HanXiSHEN(DepartmentofChemistry,Nan... | Liu, SJ Shen, HX Ding, XC Feng, JX | 1995 | Chinese Chemical Letters1995，6，11： | 0 |
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