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| 1 | 肿瘤坏死因子α基因多态性与中国人自身免疫肝病相关性研究显示文摘目的 探讨肿瘤坏死因子α(TNFα)启动子基因多念性与中国人自身免疫性肝炎(AIH)、原发性胆汁性肝硬化(PBC)发病的相关性。 方法 采用序列特异性聚合酶链式反应方法分析49例AIH、58例PBC患者外周血单核细胞基因组DNA TNFα启动子-308、238 G/A基因多态性,并与160例正常对照组比较。 结果 正常对照组中国人与白种人TNFα*2携带率差异较大。虽然从百分率上可以看出中国人PBC患者TNF α*2携带率低于正常对照组(10.34%与16.88%),但统计学上两者差异无显著性,TNFα-238位基因多态性分布也与正常对照组差异无显著性;AIH患者TNF α自动子-308、-238 G/A基因多态性均与正常人差异无显著性。 结论 不同人种自身免疫肝病的免疫相关基因不同,中国人AIH、PBC与TNFα启动子基因的多态性间不存在基因连锁关系。 | 范列英 仲人前 屠小卿 Thomas Pfeiffer Ralph Feltens 朱烨 周琳 | 2004 | 中华肝脏病杂志2004,12,3: | 15 |
| 2 | 维生素D受体基因多态性与中国人自身免疫肝病相关性研究显示文摘目的 探讨维生素D受体 (VDR)基因多态性与中国人自身免疫性肝炎 (AIH)和原发性胆汁性肝硬化 (PBC)发病的相关性。方法 采用限制性长度多态性分析 (restrictionfragmentlengthpolymorphismanalysis ,RFLP)法分析 4 9例AIH、5 8例PBC患者外周血单核细胞基因组DNAVDR外显子2和外显子 7~外显子 9处限制性内切酶FokI、BsmI、ApaI和TaqI基因多态性 ,并与 16 0例正常对照组比较。结果 FokI基因多态性与AIH相关 ,AIH患者ff表型携带者明显高于正常对照组 (34 7%vs18 8% ,P =0 0 19) ;BsmI基因多态性与PBC相关 ,PBC患者携带Bb表型者较正常人明显降低(5 2 %vs 17 5 % ,P =0 0 2 1) ,而bb表型者明显升高 (94 8%vs 80 6 % ,P =0 0 1)。结论 研究结果表明VDR基因多态性与中国人AIH、PBC发病间存在基因连锁。虽然VDR基因表型分布不同 ,但不同人种 ,包括高加索人均存在相似的基因连锁。 | 范列英 仲人前 屠小卿 朱烨 弓长丽 周琳 赵智贤 Ralph Feltens Thomas Pfeiffer | 2003 | 中华医学杂志2003,83,21: | 8 |
| 3 | Complementarity among species in horizontal versus vertical rooting space显示文摘Aims Many experiments have shown a positive effect of species richness on productivity in grassland plant communities.However,it is poorly understood how environmental conditions affect this relationship.We aimed to test whether deep soil and limiting nutrient conditions increase the complementarity effect(CE)of species richness due to enhanced potential for resource partitioning.Methods We grew monocultures and mixtures of four common grassland species in pots on shallow and deep soil,factorially combined with two nutrient levels.Soil volume was kept constant to avoid confounding soil depth and volume.Using an additive partitioning method,we separated biodiversity effects on plant productivity into components due to species complementarity and dominance.Important findings Net biodiversity and complementarity effects were consistently higher in shallow pots,which was unexpected,and at the low nutrient level.These two results suggest that although belowground partitioning of resources was important,especially under low nutrient conditions,it was not due to differences in rooting depths.We conclude that in our experiment(i)horizontal root segregation might have been more important than the partitioning of rooting depths and(ii)that the positive effects of deep soil found in other studies were due to the combination of deeper soil with larger soil volume. | Stefanie von Felten Bernhard Schmid | 2008 | Journal of Plant Ecology2008,1,1: | 6 |
| 4 | 严重创伤病人心肌肌钙蛋白Ⅰ释放的发生率及其意义显示文摘 | Alain R.Edouard Marie-Louise Felten Jean-Louis Hebert Claudine Cosson Laurent Martin Dan Benhamou 钟敏(译) 曾因明(审) | 2005 | 国外医学(麻醉学与复苏分册)2005,26,1: | 6 |
| 5 | Evaluation of three techniques for detection of low-level methicillin-resistant Staphylococcus aureus (MRSA) : a disk diffusion method with cefoxitin and moxalactam,the Vitek 2 system, and the MRSA-Screen latex agglutination test 显示文摘 | FELTEN A GRANDRY B LAGRANGE P H | 2002 | J Clin Microbiol2002,40,8: | 1 |
| 6 | Direct and inverse estimates for Bernstein polynomials显示文摘 | Felten M | 1998 | Constr Approx1998,14,: | 1 |
| 7 | Evaluation of three techniques for detetion of low - level methicillin - resistant Staphylococcus aureus (MRA):a disk diffusion method with cefoxitin and mexalactam , the Vitek 2 system, and the MRSA - screen latex agglutination test显示文摘 | Felten A Grandry B Lagrange P H | 2002 | Clin Microbiol2002,40,8: | 1 |
| 8 | Use of platinum and rhodium to improve oxide adherence on Ni-8Cr-6Al Alloys显示文摘 | Felten E J Pettit F S | 1976 | Oxidation of Metals1976,10,1: | 1 |
| 9 | Monitoring Response to Radiotherapy in Human Squamous Cell Cancer Bearing Nude Mice: Comparison of 2′-deoxy-2′-[18F]fluoro-d-glucose (FDG) and 3′-[18F]fluoro-3′-deoxythymidine (FLT)显示文摘 | Carla F. M. Molthoff Bianca M. Klabbers Johannes Berkhof Jasper T. Felten Marcelle Gelder Albert D. Windhorst Ben J. Slotman Adriaan A. Lammertsma | 2007 | Molecular Imaging and Biology2007,,6: | 1 |
| 10 | Numerical modeling of electrognetically-riven turbulent flows using LES methods 显示文摘 | FELTEN F FAUTRELLE Y TERRAIL Y D | 2004 | Applied Mathematical Modelling2004,28,1: | 1 |
| 11 | Noradrenergic lympatheticneural interactions with the immune system: structure and function显示文摘 | Felten DL Fehen SY Bellinger DL | 1987 | Immunol Rev1987,100,5: | 1 |
| 12 | Alloyed thick film gold conductor for high-reliability high-yield wire bonding显示文摘 | HOROWITZ S FELTEN J GERRY D | 1979 | IEEE Transactions on Components and Packaging Technologies1979,2,4: | 1 |
| 13 | Evalution of three techniques for detection of low-level methicillin-resistant Staphylococcus aureus: a disk diffusion method with cefoxitin and moxalactam, the Vitek 2 system, and the MRSA-Screen latex agglutination test 显示文摘 | FELTEN A GRANDRY B LAGRANGE PH | 2002 | J Clin Microbiol2002,40,8: | 1 |
| 14 | Students as co-creators of teaching Approaches, course design, and curricula: implications for academicdevel- opers 显示文摘 | Bovill C Cook-Sather A Felten P | 2011 | Intemational Journal for Academic Development2011,16,2: | 1 |
| 15 | Skeptical view of DRM and fair use显示文摘 | Felten E | 2003 | Communications of the ACM2003,46,4: | 1 |
| 16 | Numerical modelling of electro- gnetically-riven turbulent flows using LES methods 显示文摘 | Felten F Fautrelle Y Du Terrail Y Metais O | 2004 | Applied Mathematical Modelling2004,28,1: | 1 |
| 17 | WO3 films modified with functionalised multi-wall carbon nanotubes: Morphological, compositional and gas response studies显示文摘 | Bittencourt C Felten A Espinosa E H | 2006 | Sensors and Actuators B2006,115,1: | 1 |
| 18 | Understanding trusted computing; will its benefits outweigh its drawbacks 显示文摘 | Felten E W | 2003 | Security & Privacy Magazine (IEEE)2003,1,3: | 1 |
| 19 | IdentificationofTLC markers and quantification by HPLC-MS of various con-stituents in noni fruit powder and commercial noni-derived pro-ducts 显示文摘 | Potterat O Felten RV Dalsgaard PW | 2007 | J Agric Food Chemy2007,55,18: | 1 |
| 20 | Psychoneuroimmunology:interactions between the nervous system and the immune system显示文摘 | Ader R Cohen N Felten D | 1995 | Lancet1995,345,8942: | 1 |