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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomised, clinical SYNTAX trial显示文摘 | Friedrich W Mohr Marie-Claude Morice A Pieter Kappetein Ted E Feldman Elisabeth St?hle Antonio Colombo Michael J Mack David R Holmes Marie-angèle Morel Nic Van Dyck Vicki M Houle Keith D Dawkins Patrick W Serruys | 2013 | The Lancet . 2013 (9867)2013，，9867： | 2 |
| 3 | Molecular phy- logenetie characterization of microbial community imbalances in human inflammatory bowel diseases显示文摘 | Frank DN St Amand AL Feldman RA | 2007 | Proc Natl Acad Sei USA2007，104，13： | 1 |
| 4 | Stimulation of DNA synthesis and c-fos expression in corneal endothelium by insulin or insulin-like growth factor-I显示文摘 | Feldman ST Gately D Seely BL | 1993 | Invest Ophthalmol Vis Sci1993，34，6： | 1 |
| 5 | Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomised, clinical SYNTAX trial显示文摘 | Friedrich W Mohr Marie-Claude Morice A Pieter Kappetein Ted E Feldman Elisabeth St?hle Antonio Colombo Michael J Mack David R Holmes Marie-angèle Morel Nic Van Dyck Vicki M Houle Keith D Dawkins Patrick W Serruys | 2013 | The Lancet2013，，9867： | 1 |
| 6 | Molecular-phy- logenetic characterization of microbial community imbalances in human inflammatory bowel diseases显示文摘 | Frank DN St Amand AL Feldman RA | 2007 | Proc Natl Acad Sci U S A2007，104，13： | 1 |
| 7 | Molecular - phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases 显示文摘 | FRANF D N St AMANDA L FELDMAN R A | 2007 | Pmc Nat[ Acad Sci USA2007，104，13： | 1 |
| 8 | , Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases 显示文摘 | Frank DN St Amand AL Feldman RA | 2007 | Proc Natl Acad Sci USA2007，104，13： | 1 |
| 9 | Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases 显示文摘 | Frank DN St Amand AL Feldman RA | 2007 | Proc N atl Acad Sci USA2007，104，13： | 1 |
| 10 | Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomised, clinical SYNTAX trial显示文摘 | Friedrich W Mohr Marie-Claude Morice A Pieter Kappetein Ted E Feldman Elisabeth St?hle Antonio Colombo Michael J Mack David R Holmes Marie-angèle Morel Nic Van Dyck Vicki M Houle Keith D Dawkins Patrick W Serruys | 2013 | The Lancet2013，，9867： | 1 |
| 11 | Anterior-posterior strain variation in normally hydrated and swollen rabbit cornea 显示文摘 | Hennighausen H Feldman ST Bille JF | 1998 | Invest Ophthalmol Vis Sci1998，39，2： | 1 |
| 12 | Anatomical and clinical characteristics to guide decision making between coronary artery bypass surgery and percutaneous coronary intervention for individual patients: development and validation of SYNTAX score II显示文摘 | Vasim Farooq David van Klaveren Ewout W Steyerberg Emanuele Meliga Yvonne Vergouwe Alaide Chieffo Arie Pieter Kappetein Antonio Colombo David R Holmes Michael Mack Ted Feldman Marie-Claude Morice Elisabeth St?hle Yoshinobu Onuma Marie-angèle Morel Hector | 2013 | The Lancet2013，，9867： | 1 |
| 13 | Moleeular-phylogenetie characterization of microbial community imbalanees in human in- flammatory bowel diseases 显示文摘 | Frank DN St Amand AL Feldman RA | 2007 | Proe Natl Aead Sei USA2007，104，13： | 1 |
| 14 | Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases显示文摘 | Frank DN St Amand AL Feldman RA | 2007 | Proc Natl Acad Sci USA2007，104，13： | 1 |
| 15 | Anterior-posterior strain variation in normally hydrated and swollen rabbit cornea显示文摘 | Hennighausen H Feldman ST Bille JF | 1998 | Invest Ophthalmol Vis Sci1998，39，： | 1 |
| 16 | Molecular-phylogenetic characterization of microbialcommunity imbalances in human inflammatory bowel disea-ses 显示文摘 | Frank DN St Amand AL Feldman RA etal | 2007 | Proc Natl Acad Sci USA2007，104，13： | 1 |
| 17 | Molecular-phyloge-netic characterization of microbial community imbalances in humaninflammatory bowel diseases显示文摘 | Frank DN St Amand AL Feldman RA | 2007 | Proc Natl Acad Sci U S A2007，104，13： | 1 |
| 18 | Molecular-phyloge-netic characterization of microbial community imbalances in human inflammatory bowel diseases显示文摘 | Frank DN St Amand AL Feldman RA | | 0，，： | 1 |
| 19 | Five-Year Outcomes in Patients With Left Main Disease Treated With Either Percutaneous Coronary Intervention or Coronary Artery Bypass Grafting in the Synergy Between Percutaneous Coronary Intervention With Taxus and Cardiac Surgery Trial显示文摘 | Marie-Claude Morice Patrick W. Serruys A. Pieter Kappetein Ted E. Feldman Elisabeth St?hle Antonio Colombo Michael J. Mack David R. Holmes James W. Choi Witold Ruzyllo Grzegorz Religa Jian Huang Kristine Roy Keith D. Dawkins Friedrich Mohr | 2014 | Circulation2014，，： | 1 |
| 20 | Treatment of postherpetic neuralgia显示文摘 | Frucht PJ Feldman ST Brown SI | 1997 | Acta Ophthalmol Scand1997，75，： | 1 |
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