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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | The Internet Revolution and the Geography of Innovation显示文摘 | Feldman M P | 2002 | International Social Sciences Journal2002，54，3： | 1 |
| 3 | Competing on standards? Entrepreneurship, intellectual property, and platform technologies 显示文摘 | Simcoe T Graham S J H Feldman M P | 2009 | Journal of Economics & Management Strategy2009，18，： | 1 |
| 4 | Psychopathology in offspring of mothers with borderline personality disorder:a pilot study显示文摘 | Weiss M Zelkowitz P Feldman RB | 1996 | Can J Psychiatry1996，41，5： | 1 |
| 5 | Central cardiovascular effects of alpha-adrenergic drugs: differences between catecholamines and imidazolines 显示文摘 | Bousquet P Feldman J Schwartz J | 1984 | J Pharmacol Exp Ther1984，230，1： | 1 |
| 6 | Validation of a physical activity questionnaire (CHAMPS) as an indicator of postoperative recovery after laparoscopic cholecystectomy 显示文摘 | Feldman LS Kaneva P Demyttenaere S | 2009 | Surgery2009，146，1： | 1 |
| 7 | The Ex-ante assess- ment of knowledge spillovers: government R&D policy, economic incentives and private firm behavior显示文摘 | FELDMAN M P KELLEY M R | 2006 | Re- search Policy2006，35，10： | 1 |
| 8 | The new economies of innovation, spillovers and agglomeration : a review of empirical studies 显示文摘 | FELDMAN M P | 1999 | Economics of Inno- vation and New Technology1999，，08： | 1 |
| 9 | R&D Spillovers and the Geography of Innovation and Production显示文摘 | Audretsch D B Feldman M P | 1996 | The American Economic Review1996，，： | 1 |
| 10 | High temperature, high pressure electrostatic precipitation显示文摘 | Bush J R Feldman P L Robinson M | 1979 | Journal of the Air Pollution Control Association1979，29，4： | 1 |
| 11 | Creating a Cluster while Building a Firm : Entrepreneurs and the Formation of Industrial Clusters 显示文摘 | Feldman M P Francis J Bercovitz J | 2005 | Regional Studies2005，39，： | 1 |
| 12 | Knowledge Spillovers and The Geography of Innovation and Production显示文摘 | M P FELDMAN | 1996 | American Economic Review1996，86，： | 1 |
| 13 | Innovation in Cities:Science-based Diversity,Specialization and Localized Competition显示文摘 | Feldman M P Audretsch D B | 1999 | European Economic Review1999，43，： | 1 |
| 14 | Innovation in Cities: Science-Based Diversity, Specialization and Localized Competition 显示文摘 | AUDRETSCH D B FELDMAN M P | 1999 | European Economic Re- view1999，43，2： | 1 |
| 15 | Antiangiogenic gene therapy of cancer utilizing a recombinant adenovirus to elevate systemic endostatin levels in mice显示文摘 | Feldman A L Restifo N P Alexander H R | 2000 | Cancer Res2000，，60： | 1 |
| 16 | Decliningprevalence of cervicovaginal human papillomavirus infection with age is independent of other fish factors显示文摘 | Burk RD Kelly P Feldman J | 1996 | Sex Transm Dis1996，23，4： | 1 |
| 17 | Innovation in Cities: Science-based Diversity, Specialization and Localized Competition 显示文摘 | Feldman Maryann P & Audretsch David B | 1999 | European Economic Review1999，43，2： | 1 |
| 18 | Hierarchi- cal task assignment and communication algorithms for unmanned aerial vehicle flocks 显示文摘 | BEN-ASHER Y FELDMAN S GURFIL P | 2008 | Jouranl of Aerospace Computing Informantion and Communication2008，5，8： | 1 |
| 19 | The Entrepreneurial Event Revisited: Finn Formation in a Regional Context 显示文摘 | Feldman M P | 2001 | Industrial and Corporate Change2001，10，4： | 1 |
| 20 | Incomplete resolution of ST-segment elevation is a marker of transient microcirculatory dysfunction after stenting for acute myocardial infarction显示文摘 | Feldman LJ Coste P Furber A | 2003 | Circulation2003，107，： | 1 |
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