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12篇 您的检索式：作者名="Farthmann"

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		题名	作者	年代	出处	被引量
	1	Mesh implantation for pelvic or- gan prolapse improves quality of life显示文摘	Yesil N Watennann K Farthmann J	2014	Arch Obstet Gyneco12014，289，4：	1
	2	EXPRESSION OF FLIP IN HUMAN COLON CARCINOMAS: A NEW MECHANISM OF IMMUNE EVASION显示文摘Objective: It has been proposed that Fas ligand (FasL) may play an important role in immune escape of tumors and FLIP is an important mediator of Fas/FasL pathway. In this study, the expression of FLIP was determined in human colon carcinoma cell lines and tissue to investigate the new mechanism of immune evasion of human colon carcinomas. Methods: RT-PCR and immunohistochemistry (IHC) were performed to investigate the expression of FLIP in human colon carcinoma cell lines SW480, LS174 and twenty human primary colon carcinoma specimens. Results: It was shown that SW480 cells, LS174 cells and primary colon carcinoma specimen constitutively expressed FLIP at the mRNA and protein level. The expression of FLIP was not found in the epithelial cells of normal colon mucosa. Conclusion: FLIP was expressed in human primary colon carcinoma specimens but not in the normal counterpart. It suggested that the expression of FLIP may occur during the malignant transformation from normal colon epithelial cells to colon carcinoma cells. Tumor cells might obtain the ability to resist the Fas-mediated apoptosis by expressing FLIP. The expression of FLIP might contribute to the formation of colon carcinomas.	邢宝才 S. Wimmenauer EH. Farthmann	2005	Chinese Journal of Cancer Research2005，17，3：	1
	3	Video-assisted thoracic surgery (VATS) evaluation of intrathoracic disease in patients with FIGO III and IV stage ovarian cancer显示文摘	Klar M Farthmann J Bossart M	2012	Gynecol Oncol2012，126，3：	1
	4	FasL EXPRESSION IN HUMAN COLON CARCINOMAS显示文摘Objective: The Fas and Fas ligand (FasL) play an important role in maintaining immune privilege on malignant tumors. In present study, we investigated the expression of FasL in SW480 and LS174 human colon carcinoma cell lines and twenty primary colon carcinoma specimens. Methods: The expression of FasL in human colon carcinoma cell lines and primary colon carcinomas specimens was detected by immunohistochemistry and Reverse Transcription-PCR (RT-PCR). Results: We found that all of detected human colon carcinoma cell lines and primary colon carcinoma specimens constitutively expressed FasL at the mRNA and protein level. However, the expression of FasL was not found in normal colon epithelial cells. Conclusion: The expression of FasL may occur during malignant transformation from normal colon epithelial cells to colon carcinoma cells. Our results suggest that tumor cells kill cytotoxic T lymphocytes (CTLS) and natural killer (NK) cells by expression of FasL. It may be a new mechanism for tumor cells to escape the host’s immune surveillance. The expression of FasL may contribute to the formation of colon carcinomas.	邢宝才王怡 S Wimmenauer E H Farthmann 黄信孚	2002	Chinese Journal of Cancer Research2002，14，1：	1
	5	Fractures in neo nates as a result of birth trauma caused by caesarean section 显示文摘	Rasenack R M? llmann C Farthmann J	2010	Z Geburtshilfe Neonatol2010，214，5：	1
	6	Mesh implantation for pelvic organ prolapse improves quality of life 显示文摘	Yesil N Watermann K Farthmann J	2014	Arch Obstet Gynecol2014，289，4：	1
	7	Video-assisted thoracic surgery(VATS)evaluation of intrathoracic disease in patients with FIGO III and IV stage ovarian cancer显示文摘	Klar M Farthmann J Bossart M	2012	Gynecologic Oncology:An International Journal2012，126，3：	1
	8	Elevated plasma levels of transforming growth factor (TGF)-betal and TGF-beta2 in patients with disseminated malignant melanoma 显示文摘	Krasagakis K Th? lke D Farthmann B	1998	Br J Cancer1998，77，9：	1
	9	Epidemiology and pathophysiology of intra abdominal infections (IAI)显示文摘	Farthmann EH Schoffel U	1998	Infection1998，26，5：	1
	10	Prognostic relevance of uPAR-del4/5 and TIMP-3 mRNA expression levels in breast cancer显示文摘	Kotzsch M Farthmann J Meye A	2005	Eur J Cancer2005，41，17：	1
	11	Detection of biliary origin of acute pancreatitis显示文摘	Prof. Dr. Jürgen Sch?lmerich MD Volker Gross MD Thorstein Johannesson MD Günter Brobmann MD Klaus Rückauer MD Bertold Wimmer MD Wolfgang Gerok MD Eduard Heinrich Farthmann MD	1989	Digestive Diseases and Sciences1989，，6：	1
	12	Prognostic relevance of uPARdel4/5 and TIMP-3 mRNA expression levels in breast cancer显示文摘	Kotzsch M Farthmann J Meve A	2005	Eur J Cancer2005，41，17：	1

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