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| 1 | Modeling the influence of forced ventilation on the dispersion of droplets ejected from roadheader-mounted external sprayer显示文摘In order to reveal the influence of forced ventilation on the dispersion of droplets ejected from roadheader-mounted external sprayer,the paper studies the air-flowing field and the droplet distribution under the condition of gentle breeze and normal forced ventilation in heading face using the particle tracking technology of computational fluid dynamics(CFD).The results show that air-flowing tendency in the same section presents great comparability in the period of gentle breeze and forced ventilation,and the difference mainly embodies in the different wind velocity.The influence of ventilation on the dispersion of droplets is faint under the gentle breeze condition.The droplet can be evenly distributed around the cutting head.However,under the normal forced ventilation,a large number of droplets will drift to the return air side.At the same time,droplet clusters are predominantly presented in the lower part of windward side and the middle of the leeward side around the cutting head.In contrast,the droplet concentration in other parts around cutting head decreases a lot and the droplets are unable to form close-grained mist curtain.So the dust escape channel is formed.In addition,the simulation results also reveal that the disturbance of air flow on the droplet distribution can be effectively relieved when using ventilation duct with Coanda effect(VDCE).Field experiment results show that the dust suppression efficiency of total dust and respirable dust increases respectively by 10.5%and 9.3%when using VDCE,which proves that it can weaken the influence of airflow on droplet dispersion. | Han Fangwei Wang Deming Jiang Jiaxing Zhu Xiaolong | 2014 | International Journal of Mining Science and Technology2014，24，1： | 10 |
| 2 | A new design of foam spray nozzle used for precise dust control in underground coal mines显示文摘In order to improve the utilization rate of foam,an arc jet nozzle was designed for precise dust control.Through theoretical analysis,the different demands of foam were compared amongst arc jets,flat jets and full cone jets when the dust source was covered identically by foam.It is proved that foam consumption was least when an arc jet was used.Foam production capability of an arc jet nozzle under different conditions was investigated through experiments.The results show that with the gas liquid ratio(GLR)increasing,the spray state of an arc jet nozzle presents successively water jet,foam jet and mist.Under a reasonable working condition range of foam production and a fixed GLR,foam production quantity increases at first,and then decreases with the increase of liquid supply quantity.When the inner diameter of the nozzle is 14 mm,the best GLR is 30 and the optimum liquid supply quantity is0.375 m^3/h.The results of field experiments show that the total dust and respirable dust suppression efficiency of arc jet nozzles is 85.8%and 82.6%respectively,which are 1.39 and 1.37 times higher than the full cone nozzles and 1.20 and 1.19 times higher than the fiat nozzles. | Han Fangwei Wang Deming Jiang Jiaxing Zhu Xiaolong | 2016 | International Journal of Mining Science and Technology2016，26，2： | 4 |
| 3 | Application of foam to suppress rock dust in a large cross-section rock roadway driven with roadheader显示文摘 | Hetang Wang Deming Wang Wanxing Ren Xinxiao Lu Fangwei Han Yikun Zhang | 2013 | Advanced Powder Technology2013，，1： | 1 |
| 4 | Neutrosophic Adaptive Clustering Optimization in Genetic Algorithm and Its Application in Cubic Assignment Problem显示文摘In optimization theory,the adaptive control of the optimization process is an important goal that people pursue.To solve this problem,this study introduces the idea of neutrosophic decision-making into classical heuristic algorithm,and proposes a novel neutrosophic adaptive clustering optimization thought,which is applied in a novel neutrosophic genetic algorithm(NGA),for example.The main feature of NGA is that the NGA treats the crossover effect as a neutrosophic fuzzy set,the variation ratio as a structural parameter,the crossover effect as a benefit parameter and the variation effect as a cost parameter,and then a neutrosophic fitness function value is created.Finally,a high order assignment problem in warehousemanagement is taken to illustrate the effectiveness of NGA. | Fangwei Zhang Shihe Xu Bing Han Liming Zhang Jun Ye | 2023 | Computer Modeling in Engineering & Sciences2023，，3： | 0 |
| 5 | Use of recombinant microRNAs as antimetabolites to inhibit human non-small cell lung cancer显示文摘During the development of therapeutic microRNAs(miRNAs or miRs),it is essential to define their pharmacological actions.Rather,miRNA research and therapy mainly use miRNA mimics synthesized in vitro.After experimental screening of unique recombinant miRNAs produced in vivo,three lead antiproliferative miRNAs against human NSCLC cells,miR-22-3p,miR-9-5p,and miR-218-5p,were revealed to target folate metabolism by bioinformatic analyses.Recombinant miR-22-3p,miR-9-5p,and miR-218-5p were shown to regulate key folate metabolic enzymes to inhibit folate metabolism and subsequently alter amino acid metabolome in NSCLC A549 and H1975 cells.Isotope tracing studies further confirmed the disruption of one-carbon transfer from serine to folate metabolites by all three miRNAs,inhibition of glucose uptake by miR-22-3p,and reduction of serine biosynthesis from glucose by miR-9-5p and-218-5p in NSCLC cells.With greater activities to interrupt NSCLC cell respiration,glycolysis,and colony formation than miR-9-5p and-218-5p,recombinant miR-22-3p was effective to reduce tumor growth in two NSCLC patient-derived xenograft mouse models without causing any toxicity.These results establish a common antifolate mechanism and differential actions on glucose uptake and metabolism for three lead anticancer miRNAs as well as antitumor efficacy for miR-22-3p nanomedicine,which shall provide insight into developing antimetabolite RNA therapies. | Yixin Chen Mei-Juan Tu Fangwei Han Zhenzhen Liu Neelu Batra Primo N.Lara Hong-Wu Chen Huichang Bi Ai-Ming Yu | 2023 | Acta Pharmaceutica Sinica B2023，13，10： | 0 |
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