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| 1 | Effect of transjugular intrahepatic portosystemic shunt on pulmonary gas exchange in patients with portal hypertension and hepatopulmonary syndrome显示文摘AIM: To assess the impact of transjugular intrahepatic portosystemic shunt (TIPS) on pulmonary gas exchange and to evaluate the use of TIPS for the treatment of hepatopulmonary syndrome (HPS).METHODS: Seven patients, three of them with advanced HPS, in whom detailed pulmonary function tests were performed before and after TIPS placementat the University of Alabama Hospital and at the Hospital Clinic, Barcelona, were considered.RESULTS: TIPS patency was confirmed by hemodynamic evaluation. No changes in arterial blood gases were observed in the overall subset of patients. Transient arterial oxygenation improvement was observed in only one HPS patient, early after TIPS, but this was not sustained 4 mo later.CONCLUSION: TIPS neither improved nor worsened pulmonary gas exchange in patients with portal hypertension. This data does not support the use of TIPS as a specific treatment for HPS. However, it does reinforce the view that TIPS can be safely performed for the treatment of other complications of portal hypertension in patients with HPS. | Graciela Martínez-Pallí Britt B Drake Joan-Carles García-Pagán Joan-Albert Barberà Miguel R Arguedas Robert Rodriguez-Roisin Jaume Bosch Michael B Fallon | 2005 | World Journal of Gastroenterology2005，11，43： | 11 |
| 2 | Gender and racial differences in nonalcoholic fatty liver disease显示文摘Due to the worldwide epidemic of obesity, nonalcoholic fatty liver disease(NAFLD) has become the most com-mon cause of elevated liver enzymes. NAFLD represents a spectrum of liver injury ranging from simple steato-sis to nonalcoholic steatohepatitis(NASH) which may progress to advanced fibrosis and cirrhosis. Individuals with NAFLD, especially those with metabolic syndrome, have higher overall mortality, cardiovascular mortality, and liver-related mortality compared with the general population. According to the population-based studies, NAFLD and NASH are more prevalent in males and in Hispanics. Both the gender and racial ethnic differences in NAFLD and NASH are likely attributed to interaction between environmental, behavioral, and genetic fac-tors. Using genome-wide association studies, several genetic variants have been identified to be associated with NAFLD/NASH. However, these variants account for only a small amount of variation in hepatic steatosis among ethnic groups and may serve as modifiers of the natural history of NAFLD. Alternatively, these variants may not be the causative variants but simply markers representing a larger body of genetic variations. In this article, we provide a concise review of the gender and racial differences in the prevalence of NAFLD and NASHin adults. We also discuss the possible mechanisms for these disparities. | Jen-Jung Pan Michael B Fallon | 2014 | World Journal of Hepatology2014，6，5： | 10 |
| 3 | Vanishing bile duct syndrome in human immunodeficiency virus: Nevirapine hepatotoxicity revisited显示文摘Vanishing bile duct syndrome (VBDS) refers to a group of disorders characterized by prolonged cholestasis as a result of destruction and disappearance ofintrahepatic bile ducts. Multiple etiologies have been indentifi ed including infections, neoplastic disorders, autoimmune conditions and drugs. The natural history of this condition is variable and may involve resolution of cholestasis or progression with irreversible damage. VBDS is extremely rare in human immunodeficiency virus (HIV)-infected patients and anti-retroviral therapy has never been implicated as a cause. We encountered a young pregnant female with HIV and VBDS secondary to anti-retroviral therapy. Here, we report her clinical course and outcome. | Rajan Kochar Moises I Nevah Frank J Lukens Michael B Fallon Victor I Machicao | 2010 | World Journal of Gastroenterology2010，16，26： | 6 |
| 4 | Screening for hepatocellular carcinoma in patients with hepatitis C cirrhosis: a cost-utility analysis显示文摘 | Miguel R Arguedas Victor K Chen Mohamad A Eloubeidi Michael B Fallon | 2003 | The American Journal of Gastroenterology2003，，3： | 3 |
| 5 | Pulmonary Dysfunction in Chronic Liver Disease显示文摘 | Michael B Fallon Gary A Abrams | 2000 | Hepatology2000，，4： | 2 |
| 6 | Auditory hair cell explant co-cultures promote the differentiation of stem ceils into bipolar neurons显示文摘 | Coleman B Fallon JB Gillespie LN | 2007 | Exp Cell Res2007，313，： | 1 |
| 7 | Use of monodispersed, fluorescently labeled bacteria to estimate in situ protozoan bacterivory显示文摘 | SHERR B F SHERR E B FALLON R D | 1987 | ApplEnvir Microbiol1987，53，： | 1 |
| 8 | Chemoenzymatic production of 1, 5-dimethyl-2-piperidone显示文摘 | COOLING F B FAGER S K FALLON R D | 2001 | Journal of Molecular Catalysis B: Enzymatic2001，11，46： | 1 |
| 9 | Enhanced discrimination of ma-lignant from benign pancreatic disease by measuring the CA 19-9antigen on specific protein carriers显示文摘 | Yue T Maupin K A Fallon B | 2011 | PloS one2011，6，29： | 1 |
| 10 | Recurrent spontaneous cervical artery dissection显示文摘 | Schievink WI Mokri B O'Fallon WM | 1994 | N Engl J Med1994，330，6： | 1 |
| 11 | Methylene blue and cirrhosis:pathophysiologic insights,therapeutic dilemmas 显示文摘 | Michael B Fallon M D | 2000 | Ann Inter Med2000，133，9： | 1 |
| 12 | Self-reported prepregnancy maternal body mass index and infant birth-weight 显示文摘 | Murrin C Segonds P A Fallon U B | 2007 | Ir Meal J2007，100，8： | 1 |
| 13 | Needle decom- pression to avoid tension pneumoperitoneum and hemodynamic compromise after pneumatic reduction of pediatric intussuscep- tion显示文摘 | Fallon S C Kim E S Naik Mathuria B J | 2013 | Pediatr Radiol2013，43，6： | 1 |
| 14 | A robust morphological algorithm for automatic radiation field extraction and correlation of portal images显示文摘 | WANG H Fallone B G | 1994 | Medical physics1994，21，2： | 1 |
| 15 | Noninvasive Thermometry with a Clinical XRay CT Scanner显示文摘 | Fallone B G | 1982 | Medical Physics1982，9，4： | 1 |
| 16 | Feasibility study of electret dosimetry technique显示文摘 | Fallone B G Ryner L N | 1992 | Phys Med Biol1992，37，10： | 1 |
| 17 | Pharmacotherapy of somatoform disorder显示文摘 | Fallon B A | 2004 | Psych- ogases2004，56，4： | 1 |
| 18 | Improved modeling of surface charge distributions in electret ionization chambers显示文摘 | Fallone B G | 1994 | Rev Sci instrum1994，65，3： | 1 |
| 19 | The hepatopulmonary syndrome 显示文摘 | PALMA D T FALLON M B | 2006 | J Hepatol2006，45，： | 1 |
| 20 | Recurrent spontaneous cervical-artery dissection显示文摘 | Schievink WI Mokri B O'Fallon WM | 1994 | N Engl J Med1994，330，： | 1 |
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