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| 1 | Diagnostic endoscopic ultrasonography:Assessment of safety and prevention of complications显示文摘Endoscopic ultrasonography (EUS) has gained wide acceptance as an important, minimally invasive diagnostic tool in gastroenterology, pulmonology, visceral surgery and oncology. This review focuses on data regarding risks and complications of non-interventional diagnostic EUS and EUS-guided fine-needle biopsy (EUS-FNB). Measures to improve the safety of EUS und EUS-FNB will be discussed. Due to the specific mechanical properties of echoendoscopes in EUS, there is a low but noteworthy risk of perforation. To minimize this risk, endoscopists should be familiar with the specific features of their equipment and their patients' specific anatomical situations (e.g., tumor stenosis, diverticula). Most diagnostic EUS complications occur during EUS-FNB. Pain, acute pancreatitis, infection and bleeding are the primary adverse effects, occurring in 1% to 2% ofpatients. Only a few cases of needle tract seeding and peritoneal dissemination have been reported. The mortality associated with EUS and EUS-FNB is 0.02%. The risks associated with EUS-FNB are affected by endoscopist experience and target lesion. EUS-FNB of cystic lesions is associated with an increased risk of infection and hemorrhage. Peri-interventional antibiotics are recommended to prevent cyst infection. Adequate education and training, as well consideration of contraindications, are essential to minimize the risks of EUS and EUS-FNB. Restricting EUS-FNB only to patients in whom the cytopathological results may be expected to change the course of management is the best way of reducing the number of complications. | Christian Jenssen Maria Victoria Alvarez-Sánchez Bertrand Napoléon Siegbert Faiss | 2012 | World Journal of Gastroenterology2012，18，34： | 33 |
| 2 | Managementofearlyasymptomaticgastrointestinalstromaltumorsofthe stomach显示文摘Gastrointestinal stromal tumors(GIST) are the most common mesenchymal tumors of the digestive tract. Approximately two thirds of clinically manifest tumors occur in the stomach, nearly one third in the small bowel, and the rest in the colorectal region with a few cas-es in the esophagus. GIST originate within the smooth muscle layer in the wall of the tubular gastrointestinal tract and grow mostly toward the serosa, far less often toward the mucosa. In the latter case, ulceration may develop and can cause gastrointestinal bleeding as the cardinal symptom. However, most GIST of the stomach are asymptomatic. They are increasingly detected incidentally as small intramural or submucosal tumors during endoscopy and particularly during endoscopic ultra-sound. Epidemiological and molecular genetic findings suggest that early asymptomatic GIST of the stomach(< 1 cm) show self-limiting tumorigenesis. Thus, early(< 1 cm) asymptomatic gastric GIST(synonym: micro-GIST) are found in 20%-30% of the elderly. The mostlyelderly people with early gastric GIST have an excellent GIST-specific prognosis. Patients with early GIST of the stomach can therefore be managed by endoscopic sur-veillance. | Scherübl H Faiss S Knoefel WT Wardelmann E | 2014 | World Journal of Gastrointestinal Endoscopy2014，6，7： | 23 |
| 3 | Interventional endoscopic ultrasonography: an overview of safety and complications显示文摘 | María Victoria Alvarez-Sánchez Christian Jenssen Siegbert Faiss Bertrand Napoléon | 2014 | Surgical Endoscopy2014，，3： | 2 |
| 4 | New flexible endoscopic controlled stapler technique for the treatment of Zenker's diverticulum:A case series显示文摘AIM To report about the combination and advantages of a tapler-assisted diverticulotomy performed by flexible endoscopy.METHODS From November 2014 till December 2015 17 patients(8 female, 9 male, average age 69.8 years) with a symptomatic Zenker diverticulum(mean size 3.5 cm) were treated by inserting a new 5 mm fully rotatable surgical stapler(Micro Cutter30 Xchange, Cardica Inc.) next to an ultrathin flexible endoscope through an overtube. The Patients were under conscious sedation with the head reclined in left position, the stapler placed centrally and pushed forward to the bottom of the diverticulum. The septum was divided by the staple rows under flexible endoscopic control.RESULTS In eleven patients(64.7%) the stapler successfully divided the septum completely. Mean procedure time was 21 min, medium size of the septum was 2.8 cm(range 1.5 cm to 4 cm). In four patients the septum was shorter than 3 cm, in seven longer than 3 cm. To divide the septum, averagely 1.3 stapler cartridges were used. Two minor bleedings occurred. Major adverse events like perforation or secondary haemorrhage did not occur. After an average time of two days patients were discharged from the hospital. In 6 patients(35.3%) the stapler failed due to a thick septum or insufficient reclination of the head. Follow up endoscopy was performed after an average of two months in 9 patients; 4 patients(44.4%) were free of symptoms, 5 patients(55.6%) stated an improvement. A relapse of symptoms did not occur. CONCLUSION Flexible endoscopic Zenker diverticulotomy by using a surgical stapler is a new, safe and efficient treatment modality. A simultaneously tissue opening and occlusion prevents major complications. | Johanna Wilmsen Robert Baumbach Dietmar Stüker Vincens Weingart Frank Neser Stefan Karl Golder Christof Pfundstein Ellen Claudia Notzel Thomas Rosch Siegbert Faiss | 2017 | World Journal of Gastroenterology2017，23，17： | 2 |
| 5 | S3 Guideline: Sedation for gastrointestinal endoscopy 2008显示文摘 | A. Riphaus T. Wehrmann B. Weber J. Arnold U. Beilenhoff H. Bitter S. von Delius D. Domagk A. Ehlers S. Faiss D. Hartmann W. Heinrichs M.-L. Hermans C. Hofmann S. In der Smitten M. Jung G. K?hler M. Kraus J. Martin A. Meining J. Radke T. R?sch H. Seifert A | 2009 | Endoscopy2009，，09： | 1 |
| 6 | Capsule retention: A feared complication of wireless capsule endoscopy显示文摘 | Stefanos Karagiannis Siegbert Faiss Christos Mavrogiannis | 2009 | Scandinavian Journal of Gastroenterology2009，，10： | 1 |
| 7 | Endocopic ultrasonography of neuroendocrine tumous 显示文摘 | Zimmer T Scherubl H Faiss S | 2000 | Digestion2000，62，1： | 1 |
| 8 | Capsule endoscopy in refractory celiac disease显示文摘 | S. Daum U. Wahnschaffe R. Glasenapp M. Borchert R. Ullrich M. Zeitz S. Faiss | 2007 | Endoscopy2007，，05： | 1 |
| 9 | Pancreatic panniculitis in an 88-year-old man with neuroendocrine carcinoma显示文摘 | Preiss JC Faiss S Loddenkemper C | 2002 | Digestion2002，66，3： | 1 |
| 10 | Changes in cytokinin eontent and cytokinin oxidase activity in response to derepression of ipt gene transcription in transgenic Tobacco calli and plants显示文摘 | Moryka V Faiss M Strand M Kamínek M Schmülling T | | 0，，： | 1 |
| 11 | Identifikation der Papilla Vateri mit dem Kolon-Kapselendoskop显示文摘 | S. Karagiannis C. Dücker P. Dautel J. Strubenhoff S. Faiss | 2010 | Z Gastroenterol2010，，07： | 1 |
| 12 | Endoscopic ultra- sonography of neuroendocrine tumours显示文摘 | ZIMMER T SCHERQBL H FAISS S | 2000 | Digestion2000，62，1： | 1 |
| 13 | Prospective,randomized,multicenter trial on the antiproliferative effect of lanreotide,interferon alfa,and their combination for therapy of metastatic neuroendocrine gastroenteropancreatic tumors-the International Lanreotide and Interferon Alfa Study Group显示文摘 | Faiss S Pape UF Bohmig M | | J Clin Oncol0，21，3： | 1 |
| 14 | The missed colorectal cancer problem显示文摘 | Faiss S | 2011 | Dig Dis2011，291，： | 1 |
| 15 | Last word on Point:Counterpoint:Hypobaric hypoxia induces different responses from normobaric hypoxia 显示文摘 | Millet GP Faiss R Pialoux V | 2012 | J Applied Physiology2012，112，10： | 1 |
| 16 | Interferon-α versus somatostatin or the combination of both in metastatic neuroendocrine gut and pancreatic tumours 显示文摘 | Faiss S Scherubl H Riecken EO | 2003 | Digestion2003，57，1： | 1 |
| 17 | Endoscopic ultrasonography of neuroendocrine tumors显示文摘 | Zimmer T Scherubl H Faiss S | | 0，，： | 1 |
| 18 | Formation of irreversibly bound annexin A1 protein domains on POPC/POPS solid supported membranes显示文摘 | Faiss S Kastl K Janshoff A | 2008 | Biochim Biophys Acta2008，1778，78： | 1 |
| 19 | Capsule retention: A feared complication of wireless capsule endoscopy显示文摘 | Stefanos Karagiannis Siegbert Faiss Christos Mavrogiannis | 2009 | Scandinavian Journal of Gastroenterology2009，，10： | 1 |
| 20 | Endoscopic ultrasonography of neuroendocrine tumours显示文摘 | Zimmer T Scherubl H Faiss S | 2000 | Digestion2000，62，1： | 1 |
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