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2篇 您的检索式：作者名="Fabio Forlani"

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		题名	作者	年代	出处	被引量
	1	Cytoskeleton reorganization and ultrastructural damage induced by gliadin in a three-dimensional in vitro model显示文摘AIM: To evaluate the interplay between gliadin and LoVo cells and the direct effect of gliadin on cytoskeletal patterns.METHODS: We treated LoVo multicellular spheroids with digested bread wheat gliadin in order to investigate their morphology and ultrastructure (by means of light microscopy and scanning electron microscopy), and the effect of gliadin on actin (phalloidin fluorescence)and the tight-junction protein occludin and zonula occluden-1.RESULTS: The treated spheroids had deep holes and surface blebs, whereas the controls were smoothly surfaced ovoids. The incubation of LoVo spheroids with gliadin decreased the number of intracellular actin filaments, impaired and disassembled the integrity of the tight-junction system.CONCLUSION: Our data obtained from an 'in vivolike' polarized culture system confirm the direct noxious effect of gliadin on the cytoskeleton and tight junctions of epithelial cells. Unlike two-dimensional cell culture systems, the use of multicellular spheroids seems to provide a suitable model for studying cell-cell interactions.	Ersilia Dolfini Leda Roncoroni Luca Elli Chiara Fumagalli Roberto Colombo Simona Ramponi Fabio Forlani Maria Teresa Bardella	2005	World Journal of Gastroenterology2005，11，48：	3
	2	Tolerance to the fungal pathogen Rhizoctonia solani AG4 of transgenic tobacco expressing the maize ribosome-inactivating protein b-32显示文摘	MASSIMO MADDALONI FABIO FORLANI VIRGILIO BALMAS GIOVANNA DONINI LAURENCE STASSE LUCIANA CORAZZA MARIO MOTTO	1997	Transgenic Research1997，，6：	1

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