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| 1 | Polyoxypregnanes from the stems of Marsdenia tenacissima显示文摘From the stems of Marsdenia tenacissima two new polyoxypregnanes were isolated, their structures were elucidated by 1D, 2D- NMR as 11a,12b-di-O-tigloyl-tenacigenin B (1) and tenacigenoside E(2). | Qi Fa Li Xiao Ling Wang Li Sheng Ding Chang Zhang | 2007 | Chinese Chemical Letters2007，18，7： | 8 |
| 2 | Emerging Flexible Thermally Conductive Films:Mechanism,Fabrication,Application显示文摘Effective thermal management is quite urgent for electronics owing to their ever-growing integration degree,operation frequency and power density,and the main strategy of thermal management is to remove excess energy from electronics to outside by thermal conductive materials.Compared to the conventional thermal management materials,flexible thermally conductive films with high in-plane thermal conductivity,as emerging candidates,have aroused greater interest in the last decade,which show great potential in thermal management applications of next-generation devices.However,a comprehensive review of flexible thermally conductive films is rarely reported.Thus,we review recent advances of both intrinsic polymer films and polymer-based composite films with ultrahigh in-plane thermal conductivity,with deep understandings of heat transfer mechanism,processing methods to enhance thermal conductivity,optimization strategies to reduce interface thermal resistance and their potential applications.Lastly,challenges and opportunities for the future development of flexible thermally conductive films are also discussed. | Chang‑Ping Feng Fang Wei Kai‑Yin Sun Yan Wang Hong‑Bo Lan Hong‑Jing Shang Fa‑Zhu Ding Lu Bai Jie Yang Wei Yang | 2022 | Nano-Micro Letters2022，14，8： | 6 |
| 3 | Yttria-stabilized-zirconia hollow spheres prepared by atmospheric plasma spray显示文摘Yttria-stabilizecl-zirconia(YSZ) hollow spheres are widely utilized for their novel physical and chemical properties.However,developing a simple and low-cost method for preparing such hollow spheres still remains a great challenge.In this paper,an atmospheric plasma spray(APS) method is introduced,and the formation mechanism of hollow 7YSZ(ZrO_2-7wt%Y_2O_3) spheres is presented.The hollow sphere morphology was observed by scanning electron microscopy(SEM) when agglomerated and sintered 7YSZ powders were used.Additionally,additive composition changes,phase transformations,and the thermal behavior of 7YSZ powders were analyzed by energy dispersive spectroscopy(EDS),X-ray diffractometry(XRD),thermogravimetric analysis(TG) and differential scanning calorimeter analysis(DSC).Furthermore,the phase transformations of agglomerated and sintered 7YSZ powders,7YSZ hollow spheres that annealed at various temperatures for different times are analyzed. | Xiaofeng Zhang Kesong Zhou Fa Chang Chen Song Chunming Deng Siyuan Liang | 2014 | Particuology2014，12，3： | 4 |
| 4 | Noncoding RNAs in doxorubicin-induced cardiotoxicity and their potential as biomarkers and therapeutic targets显示文摘Anthracyclines,such as doxorubicin(DOX),are well known for their high efficacy in treating multiple cancers,but their clinical usage is limited due to their potential to induce fatal cardiotoxicity.Such detrimental effects significantly impact the overall physical condition or even induce the morbidity and mortality of cancer survivors.Therefore,it is extremely important to understand the mechanisms of DOX-induced cardiotoxicity to develop methods for the early detection of cytotoxicity and therapeutic applications.Studies have shown that many molecular events are involved in DOX-induced cardiotoxicity.However,the precise mechanisms are still not completely understood.Recently,noncoding RNAs(ncRNAs)have been extensively studied in a diverse range of regulatory roles in cellular physiological and pathological processes.With respect to their roles in DOX-induced cardiotoxicity,microRNAs(miRNAs)are the most widely studied,and studies have focused on the regulatory roles of long noncoding RNAs(lncRNAs)and circular RNAs(circRNAs),which have been shown to have significant functions in the cardiovascular system.Recent discoveries on the roles of ncRNAs in DOX-induced cardiotoxicity have prompted extensive interest in exploring candidate ncRNAs for utilization as potential therapeutic targets and/or diagnostic biomarkers.This review presents the frontier studies on the roles of ncRNAs in DOX-induced cardiotoxicity,addresses the possibility and prospects of using ncRNAs as diagnostic biomarkers or therapeutic targets,and discusses the possible reasons for related discrepancies and limitations of their use. | Hong-ge Fa Wen-guang Chang Xue-juan Zhang Dan-dan Xiao Jian-xun Wang | 2021 | Acta Pharmacologica Sinica2021，42，4： | 2 |
| 5 | Tetrabutylammonium salts of tritransition-metal-substituted A-α-tungstogermanate:Halogen-free and single-component catalysts for the coupling reaction of carbon dioxide and epichlorohydrin显示文摘经由二氧化碳和 epichlorohydrin 的联合反应的 chloropropylene 碳酸盐的绿合成用 tritransition-metal-substituted A 的没有卤素、单个部件的催化剂 tetrabutylammonium 盐被完成了 -- tungstogermanate [(n-C4H9 ) 4N ] 没有任何溶剂的 3H7GeW9M3 (H2O ) 3O37 (M = CuII, NiII, CoII 和 MnII ) 。催化活动显著地被取决于在 polyoxometalates 介绍的转变金属。[(n-C4H9 ) 4N ] 3H7GeW9Mn3 (H2O ) 3O37 在 3 h 为 chloropropylene 碳酸盐为 epichlorohydrin 和 98% 选择与 94.9% 变换展出了最高催化的活动。嘴巧的机制基于结果被建议。 | Fa Wang Chen Tao Dong Xiao Fang Li Tie Gang Xu Chang Wen Hu | 2011 | Chinese Chemical Letters2011，22，7： | 2 |
| 6 | STEREOSELECTIVE TOTAL SYNTHESIS OF(±)-4α(H)-EUDESMANE显示文摘The first stereoselective total synthesis of the biomarker(±)-4α(H)-eudesmane 1,starting from(-)-carvone in five steps,has been described. | Xin CHEN Fa Jun NAN Si Chang SHAO Li Yuan MIN Tong Shuang LI Yu Lin LI Key Laboratory of Applied Organic Chemistry and Institute of Organic Chemistry,Lanzhou University,Lanzhou 730000 | 1992 | Chinese Chemical Letters1992，3，12： | 2 |
| 7 | Microvoid formation of acrylic copolymer (PAC)/cellulose acetate(CA) blend fibers显示文摘 | Xiao Chang fa | 1990 | Journal of Applied Polymer Science1990，41，： | 1 |
| 8 | Epidemiological Survey of Hemoglobinopathies Based on Next-Generation Sequencing Platform in Hunan Province,China显示文摘Objective This study was aimed at investigating the carrier rate of,and molecular variation in,α-andβ-globin gene mutations in Hunan Province.Methods We recruited 25,946 individuals attending premarital screening from 42 districts and counties in all 14 cities of Hunan Province.Hematological screening was performed,and molecular parameters were assessed.Results The overall carrier rate of thalassemia was 7.1%,including 4.83%forα-thalassemia,2.15%forβ-thalassemia,and 0.12%for bothα-andβ-thalassemia.The highest carrier rate of thalassemia was in Yongzhou(14.57%).The most abundant genotype ofα-thalassemia andβ-thalassemia was-α^(3.7)/αα(50.23%)andβ^(IVS-Ⅱ-654)/β^(N)(28.23%),respectively.Fourα-globin mutations[CD108(ACC>AAC),CAP+29(G>C),Hb Agrinio and Hb Cervantes]and sixβ-globin mutations[CAP+8(C>T),IVS-Ⅱ-848(C>T),-56(G>C),beta nt-77(G>C),codon 20/21(-TGGA)and Hb Knossos]had not previously been identified in China.Furthermore,this study provides the first report of the carrier rates of abnormal hemoglobin variants andα-globin triplication in Hunan Province,which were 0.49%and 1.99%,respectively.Conclusion Our study demonstrates the high complexity and diversity of thalassemia gene mutations in the Hunan population.The results should facilitate genetic counselling and the prevention of severe thalassemia in this region. | XI Hui LIU Qin XIE Dong Hua ZHOU Xu TANG Wang Lan TANG De Guo ZENG Chun Yan WANG Qiong NIE Xing Hui PENG Jin Ping GAO Xiao Ya WU Hong Liang ZHANG Hao Qing QIU Li FENG Zong Hui WANG Shu Yuan ZHOU Shu Xiang HE Jun ZHOU Shi Hao ZHOU Fa Qun ZHENG Jun Qing WANG Shun Yao CHEN Shi Ping ZHENG Zhi Fen MA Xiao Yuan FANG Jun Qun LIANG Chang Biao WANG Hua | 2023 | Biomedical and Environmental Sciences2023，36，2： | 1 |
| 9 | A ray tracing method for modeling indoor wave propagation and penetration显示文摘 | Chang Fa Yang Chuen Jyi Ko | 1998 | IEEE Transactions on Antennas and Propagation1998，46，6： | 1 |
| 10 | Association of HSP70 and genotoxic damage in lymphocytes of workers exposed to cokeoven emission 显示文摘 | XIAO Changfa CHEN S LI Junzhao | 2002 | Cell Stress and Chaperones2002，7，4： | 1 |
| 11 | A ray -tracing method for modeling indoor wave propagation and penetration显示文摘 | CHANG -FA Y BOAU -CHENG W CHUEN -JYI K | 1998 | An- tennas and Propagation IEEE Transactions on1998，46，6： | 1 |
| 12 | Association of IL2RA and IL2RB with rheumatoid arthritis: a replication study in a Dutch population显示文摘 | Kurreeman FA Daha NA Chang M | 2009 | Ann Rheum Dis2009，68，11： | 1 |
| 13 | Structural identification of extractables from rubber cloures used for pre-filled semisolid applicator by chromatography, mass spectrometry, and organic synthesis 显示文摘 | Fa Zhang Alan Chang Ken Karaisz | 2004 | Journal of Pharmaceutical and Biomedical Analysis2004，34，5： | 1 |
| 14 | Back-calculation of consolidation parameters from field measurements at a reclamation site显示文摘 | Ming-Fang Chang and Yung Mook Na | 2001 | Canadarn Geotechnical Journal2001，38，： | 1 |
| 15 | Prevalence and prognostic significance of acinar cell differentiation in pancreatic endocrine tumors显示文摘 | Yantiss RK Chang HK Farraye FA | 2002 | Am J Surg Pathol2002，26，7： | 1 |
| 16 | Contour - based image coding technique with its texture information reconstructed by polyline representation Signal Processing显示文摘 | FA - CHUNG L YUNG - CHANG C | 1991 | 25(1) : 81 - 891991，25，1： | 1 |
| 17 | Vibrational properties and Raman spectra of single-wall carbon nanotubes with divacancy 显示文摘 | Chang X Zhou J Fa W | 2010 | J Appl Phys2010，107，10： | 1 |
| 18 | Relationship of interleukin‐8 gene polymorphisms with hepatocellular carcinoma susceptibility and pathological development显示文摘 | Ming‐Hsien Chien Chao‐Bin Yeh Yi‐Ching Li Lin‐Hung Wei Jer‐Hwa Chang Yu‐Ting Peng Shun‐Fa Yang Wu‐Hsien Kuo | 2011 | Oncol2011，，7： | 1 |
| 19 | Electrical Resistivity of Electroless Nickel Coated Carbon Fibers显示文摘 | Shinn Shyong Tzeng Fa Yen Chang | 2001 | Thin Solid Films2001，388，： | 1 |
| 20 | High CpG island methylator phenotype is associated with lymph node metastasis and prognosis in gastric cancer显示文摘 | Chang‐HuaZhang Dong‐JieYang Jian‐JunPeng Jian‐HuiChen Fa‐KengLiu | 2012 | Cancer Science2012，，： | 1 |
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