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| 1 | 反流性食管炎中埃索美拉唑比奥美拉唑更能促进病变愈合和症状缓解显示文摘 | Kahrilas PJ Falk GW Johnson DA Schmitt C Collins DW Whipple J D’Amino D Hamelin B Joelsson B 钟捷 | 2002 | 中华消化杂志2002，22，11： | 19 |
| 2 | Transforming growth factor-β1 induces intestinal myofibroblast differentiation and modulates their migration显示文摘AIM:To investigate the effects of transforming growth factorβ1(TGF-β1)on the differentiation of colonic lamina propria fibroblasts(CLPF)into myofibroblasts in vitro. METHODS:Primary CLPF cultures were incubated with TGF-β1 and analyzed for production ofα-smooth muscle actin(α-SMA),fibronectin(FN)and FN isoforms.Migration assays were performed in a modified 48-well Boyden chamber.Levels of total and phosphorylated focal adhesion kinase(FAK)in CLPF were analyzed after induction of migration.RESULTS:Incubation of CLPF with TGF-β1 for 2 d did not changeα-SMA levels,while TGF-β1 treatment for 6 d significantly increasedα-SMA production. Short term incubation(6 h)with TGF-β1 enhanced CLPF migration,while long term treatment(6 d)of CLPF with TGF-β1 reduced migration to 15%-37% compared to untreated cells.FN and FN isoform mRNA expression were increased after short term incubation with TGF-β1(2 d)in contrast to long term incubation with TGF-β1 for 6 d.After induction of migration, TGF-β1-preincubated CLPF showed higher amounts of FN and its isoforms and lower levels of total and phosphorylated FAK than untreated cells. CONCLUSION:Long term incubation of CLPF with TGF-β1 induced differentiation into myofibroblasts with enhancedα-SMA,reduced migratory potential and FAK phosphorylation,and increased FN production.In contrast,short term contact(6 h)of fibroblasts with TGF-β1 induced a dose-dependent increase of cell migration and FAK phosphorylation without induction ofα-SMA production. | Julia Brenmoehl Sandra Nicole Miller Claudia Hofmann Daniela Vogl Werner Falk Jrgen Schlmerich Gerhard Rogler | 2009 | World Journal of Gastroenterology2009，15，12： | 12 |
| 3 | California Simulation of Evapotranspiration of Applied Water and Agricultural Energy Use in California显示文摘The California Simulation of Evapotranspiration of Applied Water (Cal-SIMETAW) model is a new tool developed by the California Department of Water Resources and the University of California, Davis to perform daily soil water balance and determine crop evapotranspiration (ET c ), evapotranspiration of applied water (ET aw ), and applied water (AW) for use in California water resources planning. ET aw is a seasonal estimate of the water needed to irrigate a crop assuming 100% irrigation efficiency. The model accounts for soils, crop coefficients, rooting depths, seepage, etc. that influence crop water balance. It provides spatial soil and climate information and it uses historical crop and land-use category information to provide seasonal water balance estimates by combinations of detailed analysis unit and county (DAU/County) over California. The result is a large data base of ET c and ET aw that will be used to update information in the new California Water Plan (CWP). The application uses the daily climate data, i.e., maximum (T x ) and minimum (T n ) temperature and precipitation (P cp ), which were derived from monthly USDA-NRCS PRISM data (PRISM Group 2011) and daily US National Climate Data Center (NCDC) climate station data to cover California on a 4 km×4 km change grid spacing. The application uses daily weather data to determine reference evapotranspiration (ET o ), using the Hargreaves-Samani (HS) equation (Hargreaves and Samani 1982, 1985). Because the HS equation is based on temperature only, ET o from the HS equation were compared with CIMIS ET o at the same locations using available CIMIS data to determine correction factors to estimate CIMIS ET o from the HS ET o to account for spatial climate differences. Cal-SIMETAW also employs near real-time reference evapotranspiration (ET o ) information from Spatial CIMIS, which is a model that combines weather station data and remote sensing to provide a grid of ET o information. A second database containing the available soil water holding capacity and soil depth information for all of California was also developed from the USDA-NRCS SSURGO database. The Cal-SIMETAW program also has the ability to generate daily weather data from monthly mean values for use in studying climate change scenarios and their possible impacts on water demand in the state. The key objective of this project is to improve the accuracy of water use estimates for the California Water Plan (CWP), which provides a comprehensive report on water supply, demand, and management in California. In this paper, we will discuss the model and how it determines ET aw for use in water resources planning. | Morteza N Orang Richard L Snyder Shu Geng Quinn J Hart Sara Sarreshteh Matthias Falk Dylan Beaudette Scott Hayes Simon Eching | 2013 | Journal of Integrative Agriculture2013，12，8： | 3 |
| 4 | 类固体非晶态材料的变形与失效显示文摘自20世纪70年代以来,类固体非晶态材料变形与失效的理论模型相继出现,这些模型基于应力驱动分子重排从而在局部流动缺陷处发生剪切转变这一物理图像.该图像是现代剪切转变区理论的基础,也是本综述的焦点.我们将首先概述该理论框架并给出一些应用案例,特别是块体金属玻璃应力−应变测量结果的阐释,剪切带数值模拟分析和剪切转变区运动方程在自由边界计算中的应用.在本综述的第二部分,为简单起见,将关注非晶塑性的非热模型,并基于该模型说明剪切转变区理论是如何从非平衡热力学的系统描述中发展起来的. | Falk M L Langer J S 陈艳(译) 王云江(校) | 2021 | 力学进展2021，51，2： | 3 |
| 5 | National Forest Inventories capture the multifunctionality of managed forests in Germany显示文摘Background:Forests perform various important ecosystem functions that contribute to ecosystem services.In many parts of the world,forest management has shifted from a focus on timber production to multi-purpose forestry,combining timber production with the supply of other forest ecosystem services.However,it is unclear which forest types provide which ecosystem services and to what extent forests primarily managed for timber already supply multiple ecosystem services.Based on a comprehensive dataset collected across 150 forest plots in three regions differing in management intensity and species composition,we develop models to predict the potential supply of 13 ecosystem services.We use those models to assess the level of multifunctionality of managed forests at the national level using national forest inventory data.Results:Looking at the potential supply of ecosystem services,we found trade-offs(e.g.between both bark beetle control or dung decomposition and both productivity or soil carbon stocks)as well as synergies(e.g.for temperature regulation,carbon storage and culturally interesting plants)across the 53 most dominant forest types in Germany.No single forest type provided all ecosystem services equally.Some ecosystem services showed comparable levels across forest types(e.g.decomposition or richness of saprotrophs),while others varied strongly,depending on forest structural attributes(e.g.phosphorous availability or cover of edible plants)or tree species composition(e.g.potential nitrification activity).Variability in potential supply of ecosystem services was only to a lesser extent driven by environmental conditions.However,the geographic variation in ecosystem function supply across Germany was closely linked with the distribution of main tree species.Conclusions:Our results show that forest multifunctionality is limited to subsets of ecosystem services.The importance of tree species composition highlights that a lack of multifunctionality at the stand level can be compensated by managing forests at the landscape level,when stands of complementary forest types are combined.These results imply that multi-purpose forestry should be based on a variety of forest types requiring coordinated planning across larger spatial scales. | Nadja K.Simons María R.Felipe-Lucia Peter Schall Christian Ammer Jürgen Bauhus Nico Blüthgen Steffen Boch François Buscot Markus Fischer Kezia Goldmann Martin M.Gossner Falk Hänsel Kirsten Jung Peter Manning Thomas Nauss Yvonne Oelmann Rodica Pena Andrea Polle Swen C.Renner Michael Schloter Ingo Schöning Ernst-Detlef Schulze Emily F.Solly Elisabeth Sorkau Barbara Stempfhuber Tesfaye Wubet Jörg Müller Sebastian Seibold Wolfgang W.Weisser | 2021 | Forest Ecosystems2021，8，1： | 2 |
| 6 | Human monocytederived macrophages induce collagen breakdown in fibrous caps of atherosclerotic plaques显示文摘 | Shah PK Falk E Badimon J J et al | 1995 | Circulation1995，92，： | 1 |
| 7 | generalized mixing model for in-itial contacting of reactive fluids显示文摘 | Villermaux J Falk L | 1994 | Chemical Engineer-ing Science1994，49，24： | 1 |
| 8 | Efficacy of sub gill give calculus removal with Er:YAG laser compared to mechanical debridement:an in situ study显示文摘 | Eberhard J Elders H Falk W | 2003 | Clin Period-onlnl2003，30，51： | 1 |
| 9 | Effects of hyperbaric oxygen on expression of fibrinolytic factors of human endothelium in a simulated ischaemia/reperfusion situation显示文摘 | Tjarnstrom J Holmdahl L Falk P | 2001 | Scand J Clin Lab Invest2001，61，3： | 1 |
| 10 | A new parallel competing reaetion system for assessing micromixing efficiency-experimental approach显示文摘 | Fournier M C Falk L Villermaux J | 1996 | Chem Eng Sci1996，51，22： | 1 |
| 11 | Involvement of NMDA receptors in alcohol-mediated behavior: Mice with reduced affinity of the NMDAR1 Glycine binding site display an attenuated sensitivity to ethanol 显示文摘 | Falk K Holger J Anja K | 2003 | Biol Psychiatry2003，53，： | 1 |
| 12 | Efficacy of subgingival calculus removal with Er:YAG laser compared to mechanical debridement:an in situ study显示文摘 | Eberhard J Ehlers H Falk W | 2003 | J Clin Periodontal2003，30，6： | 1 |
| 13 | Properties and preparation conditions of carbon nitride thin films deposited by laser CVD显示文摘 | Falk F Meinschien J Schyster K | 1998 | Carbon1998，36，5： | 1 |
| 14 | Expression of a human alpha-1,3/4-fucosyltransferase in the pit cell lineage of FVB/N mouse stomach results in production of Leb-containing glycoconjugates:a potential transgenic mouse model for studying Helicobacter pylori infection显示文摘 | Falk PG Bry L Holgersson J | 1995 | Proc Natl Acad Sci USA1995，92，5： | 1 |
| 15 | Dyna-CT during minimally invasive off-pump transapical aortic valve implantation 显示文摘 | Kempfert J Falk V Schuler G | 2009 | Ann Thorac Surg2009，88，6： | 1 |
| 16 | 2012 Revised international chapel hill consensus conference nomenclature of vasculitides 显示文摘 | Jennette JC Falk R J Bacon PA | 2013 | Arthritis Rheum2013，65，1： | 1 |
| 17 | Systemic chemothera- py with or without eetuximab in patients with reseetable eoloreetal liver metastasis: the New EPOC randomised con- trolled trial显示文摘 | Primrose J Falk S Finch-Jones M | 2014 | Lancet Oncol2014，15，6： | 1 |
| 18 | Interaction between HSP70 homolog and filamentous virions of the Beet yellows virus显示文摘 | Napuli A J Falk B W Dolja V V | 2000 | Virology2000，274，1： | 1 |
| 19 | Human monocyte derived macrophages induce collagen breaddown in fibrous caps of atherosclerotic plaque : Potential role of matrix - degrading metalloproteinases and implications for plaque rupture 显示文摘 | SHAH P K FALK E BADIMON J J | 1995 | Circulation1995，92，6： | 1 |
| 20 | Lactic acidosis in critical illness显示文摘 | Mizock B A Falk J L | 1992 | Crit Care Med1992，20，1： | 1 |
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