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| 1 | 由“到 laparoscopic 外科的桥 stenting ”的设法的尖锐 colorectal 阻塞: 我们的经验显示文摘 AIM: To verify the clinical results of the endoscopic stenting procedure for colorectal obstructions followed by laparoscopic colorectal resection with 'one stage anastomosis'. METHODS: From March 2003 to March 2009 in our surgical department, 48 patients underwent endoscopic stenting for colorectal occlusive lesion: 30 males (62.5%) and 18 females (37.5%) with an age range from 40 years to 92 years (median age 69.5). All patients enrolled in our study were diagnosed with an intestinal obstruction originating from the colorectal tract without bowel perforation signs. Obstruction was primitive colorectal cancer in 45 cases (93.7%) and benign anastomotic stricture in 3 cases (6.3%). RESULTS: Surgical resection was totally laparoscopic in 69% of cases (24 patients) while 17% (6 patients) of cases were video-assisted due to the local extension of cancer with infiltrations of surrounding structures (urinary bladder in 2 cases, ileus and iliac vessels in the others). In 14% of cases (5 patients), resection was performed by open surgery due to the high American Society of Anesthesiologists score and the elderly age of patients (median age of 89 years). We performed a terminal stomy in only 7 patients out of 35, 6 colostomies and one ileostomy (in a total colectomy). In the other 28 cases (80%), we performed bowel anastomosis at the same time as resection, employing a temporary ileostomy only in 5 cases. CONCLUSION: Colorectal stenting transforms an emergency operation in to an elective operation performable in a totally laparoscopic manner, limiting the confection of colostomy with its correlated complications. | Pierfrancesco Bonfante Luigi D’Ambra Stefano Berti Emilio Falco Massimo Vittorio Cristoni Romolo Briglia | 2012 | World Journal of Gastrointestinal Surgery2012，4，12： | 11 |
| 2 | Management of lumbar zygapophysial (facet) joint pain显示文摘AIM: To investigate the diagnostic validity and therapeutic value of lumbar facet joint interventions in managing chronic low back pain.METHODS: The review process applied systematic evidence-based assessment methodology of controlled trials of diagnostic validity and randomized controlled trials of therapeutic efficacy. Inclusion criteria encompassed all facet joint interventions performed in a controlled fashion. The pain relief of greater than 50% was the outcome measure for diagnostic accuracy assessment of the controlled studies with ability to perform previously painful movements, whereas, for randomized controlled therapeutic efficacy studies, the primary outcome was significant pain relief and the secondary outcome was a positive change in functional status. For the inclusion of the diagnostic controlled studies, all studies must have utilized either placebo controlled facet joint blocks or comparative local anesthetic blocks. In assessing therapeutic interventions, short-term and long-term reliefs were defined as either up to 6 mo or greater than 6 mo of relief. The literature search was extensive utilizing various types of electronic search media including Pub Med from 1966 onwards, Cochrane library, National Guideline Clearinghouse, clinicaltrials.gov, along with other sources includingprevious systematic reviews, non-indexed journals, and abstracts until March 2015. Each manuscript included in the assessment was assessed for methodologic quality or risk of bias assessment utilizing the Quality Appraisal of Reliability Studies checklist for diagnostic interventions, and Cochrane review criteria and the Interventional Pain Management Techniques- Quality Appraisal of Reliability and Risk of Bias Assessment tool for therapeutic interventions. Evidence based on the review of the systematic assessment of controlled studies was graded utilizing a modified schema of qualitative evidence with best evidence synthesis, variable from level Ⅰ to level Ⅴ.RESULTS: Across all databases, 16 high quality diagnostic accuracy studies were identified. In addition, multiple studies assessed the influence of multiple factors on diagnostic validity. In contrast to diagnostic validity studies, therapeutic efficacy trials were limited to a total of 14 randomized controlled trials, assessing the efficacy of intraarticular injections, facet or zygapophysial joint nerve blocks, and radiofrequency neurotomy of the innervation of the facet joints. The evidence for the diagnostic validity of lumbar facet joint nerve blocks with at least 75% pain relief with ability to perform previously painful movements was level Ⅰ, based on a range of level Ⅰ to Ⅴ derived from a best evidence synthesis. For therapeutic interventions, the evidence was variable from level Ⅱ to Ⅲ, with level Ⅱ evidence for lumbar facet joint nerve blocks and radiofrequency neurotomy for long-term improvement(greater than 6 mo), and level Ⅲ evidence for lumbosacral zygapophysial joint injections for short-term improvement only.CONCLUSION: This review provides significant evidence for the diagnostic validity of facet joint nerve blocks, and moderate evidence for therapeutic radiofrequency neurotomy and therapeutic facet joint nerve blocks in managing chronic low back pain. | Laxmaiah Manchikanti Joshua A Hirsch Frank JE Falco Mark V Boswell | 2016 | World Journal of Orthopedics2016，7，5： | 9 |
| 3 | Plasminogen kringle 5-engineered glioma cells block migration of tumor- associated macrophages and suppress tumor vascularization and progres- sion.显示文摘 | Perri SR Nalbantoglu J Annabi B Koty Z Lejeune L Francois M Di Falco MR Beliveau R Galipeau J | 2005 | 中国神经肿瘤杂志2005，3，3： | 8 |
| 4 | A case of biliary gastric fistula following percutaneous radiofrequency thermal ablation of hepatocellular carcinoma显示文摘Percutaneous radiofrequency thermal ablation (RFA) is an effective and safe therapeutic modality in the management of liver malignancies, performed with ultrasound guidance. Potential complications of RFA include liver abscess, ascites, pleural effusion, skin burn, hypoxemia, pneumothorax, subcapsular hematoma, hemoperitoneum, liver failure, tumour seeding, biliary lesions. Here we describe for the first time a case of biliary gastric fistula occurred in a 66-year old man with a Child’s class A alcoholic liver cirrhosis as a complication of RFA of a large hepatocellular carcinoma lesion in the Ⅲ segment. In the light of this case, RFA with injection of saline between the liver and adjacent gastrointestinal tract, as well as laparoscopic RFA, ethanol injection (PEI), or other techniques such as chemoembolization, appear to be more indicated than percutaneous RFA for large lesions close to the gastrointestinal tract. | Angela Falco Dante Orlando Roberto Sciarra Luciano Sergiacomo | 2007 | World Journal of Gastroenterology2007，13，5： | 6 |
| 5 | Initial assessment of chest X-ray in thoracic trauma patients: Awareness of specific injuries显示文摘AIM: To compare the reported injuries on initial assessment of the chest X-ray (CXR) in thoracic trauma patients to a second read performed by a dedicated trauma radiologist. METHODS: By retrospective analysis of a prospective database, 712 patients with an injury to the chest admitted to the University Medical Center Utrecht were studied. All patients with a CXR were included in the study. Every CXR was re-evaluated by a trauma radiologist, who was blinded for the initial results. The findings of the trauma radiologist regarding rib fractures, pneumothoraces, hemothoraces and lung contusions were compared with the initial reports from the trauma team, derived from the original patient files. RESULTS: A total of 516 patients with both thorax trauma and an initial CXR were included in the study. After re-evaluation of the initial CXR significantly more lung contusions (53.3% vs 34.1%, P < 0.001), hemothoraces (17.8% vs 11.0%, P < 0.001) and pneumothoraces (34.4% vs 26.4%, P < 0.001) were detected.During initial assessment significantly more rib fractures were reported (69.8% vs 62.3%, P < 0.001). CONCLUSION: During the initial assessment of a CXR from trauma patients in the emergency department, a significant number of treatment-dictating injuries are missed. More awareness for these specific injuries is needed. | Tjeerd S Aukema Ludo FM Beenen Falco Hietbrink Luke PH Leenen | 2012 | World Journal of Radiology2012，4，2： | 3 |
| 6 | Intravenous immune globulin suppresses angiogenesis in mice and humans显示文摘Human intravenous immune globulin(IVIg),a purified IgG fraction composed of~60%IgG1 and obtained from the pooled plasma of thousands of donors,is clinically used for a wide range of diseases.The biological actions of IVIg are incompletely understood and have been attributed both to the polyclonal antibodies therein and also to their IgG(IgG)Fc regions.Recently,we demonstrated that multiple therapeutic human IgG1 antibodies suppress angiogenesis in a target-independent manner via FcγRI,a high-affinity receptor for IgG1.Here we show that IVIg possesses similar anti-angiogenic activity and inhibited blood vessel growth in five different mouse models of prevalent human diseases,namely,neovascular age-related macular degeneration,corneal neovascularization,colorectal cancer,fibrosarcoma and peripheral arterial ischemic disease.Angioinhibition was mediated by the Fc region of IVIg,required FcγRI and had similar potency in transgenic mice expressing human FcγRs.Finally,IVIg therapy administered to humans for the treatment of inflammatory or autoimmune diseases reduced kidney and muscle blood vessel densities.These data place IVIg,an agent approved by the US Food and Drug Administration,as a novel angioinhibitory drug in doses that are currently administered in the clinical setting.In addition,they raise the possibility of an unintended effect of IVIg on blood vessels. | Reo Yasuma Valeria Cicatiello Takeshi Mizutani Laura Tudisco Younghee Kim Valeria Tarallo Sasha Bogdanovich Yoshio Hirano Nagaraj Kerur Shengjian Li Tetsuhiro Yasuma Benjamin J Fowler Charles B Wright Ivana Apicella Adelaide Greco Arturo Brunetti Balamurali K Ambati Sevim Barbasso Helmers Ingrid E Lundberg Ondrej Viklicky Jeanette HW Leusen J Sjef Verbeek Bradley D Gelfand Ana Bastos-Carvalho Sandro De Falco Jayakrishna Ambati | 2016 | Signal Transduction and Targeted Therapy2016，1，1： | 3 |
| 7 | Bayesian bootstrap quantile regression for probabilistic photovoltaic power forecasting显示文摘Photovoltaic(PV)systems are widely spread across MV and LV distribution systems and the penetration of PV generation is solidly growing.Because of the uncertain nature of the solar energy resource,PV power forecasting models are crucial in any energy management system for smart distribution networks.Although point forecasts can suit many scopes,probabilistic forecasts add further flexibility to an energy management system and are recommended to enable a wider range of decision making and optimization strategies.This paper proposes methodology towards probabilistic PV power forecasting based on a Bayesian bootstrap quantile regression model,in which a Bayesian bootstrap is applied to estimate the parameters of a quantile regression model.A novel procedure is presented to optimize the extraction of the predictive quantiles from the bootstrapped estimation of the related coefficients,raising the predictive ability of the final forecasts.Numerical experiments based on actual data quantify an enhancement of the performance of up to 2.2%when compared to relevant benchmarks. | Mokhtar Bozorg Antonio Bracale Pierluigi Caramia Guido Carpinelli Mauro Carpita Pasquale De Falco | 2020 | Protection and Control of Modern Power Systems2020，5，1： | 2 |
| 8 | Complications of Native Arteriovenous Fistula: The Role of C olor D oppler U ltrasonography显示文摘 | Bianca Visciano Eleonora Riccio Vincenzo De Falco Antonino Musumeci Ivana Capuano Andrea Memoli Antonella Di Nuzzi Antonio Pisani | 2014 | Ther Apher Dial2014，，2： | 2 |
| 9 | Effieacy of recombinant interleukin-2 (rlL-2) in patients with advanced HIV- 1 infection and blunted immune response to HAART显示文摘 | Crespo M Caragol I Falco V | 2008 | Enferm Infecc Microbiol Clin2008，26，1： | 1 |
| 10 | Melphalan,prednisone,and lenalidomide treatment for newly diagnosed myeloma:a report from the GIMEMA Italian multiple myeloma network显示文摘 | Palumbo A Falco P Corradini P | 2007 | J Clin Oncol2007，25，28： | 1 |
| 11 | 显示文摘 | Cantoni C Verdiani S Falco M | 1998 | Eur J Immunal1998，28，6： | 1 |
| 12 | SDF-1 involvement in endothelial phenotype and ischemia-induced recruitment of bone marrow progenitor cells显示文摘 | De Falco E Porcelli D Torella AR Straino S Iachininoto MG Orlandi A | 2004 | Blood2004，104，12： | 1 |
| 13 | High maternal and fetal plasma urocortin levels in pregnancies complicated by hypertension显示文摘 | Florio P Torricolli M De Falco G | 2006 | J Hypertens2006，9，： | 1 |
| 14 | Agrobiodiversi- ty, farm profits and land fragmentation: Evidence from Bulgar- ia显示文摘 | FALCO S D PENOV I ALEKSIEV A | 2010 | Land Use Policy2010，27，3： | 1 |
| 15 | Genetic divergence of a sym-patric lake-resident-anadromous three-spined stickleback Gasterosteusaculeatus species pair显示文摘 | Drevecky C J Falco R Aguirre W E | 2013 | Journal of Fish Biology2013，83，1： | 1 |
| 16 | Accuracy of High-Resolusion CT in Distinguishing between Pneumocystis Carinii Pneumonia and Non-Pneumocystis Carinii Pneumonia in AIDS Patients显示文摘 | Hidalgo A Falco V Mauleon S | 2003 | Eur Radiol2003，13，5： | 1 |
| 17 | Progress in the use of adeno-associated viral vectors for gene therapy显示文摘 | Buning H Braun Falco M Hal ek M | | 0，，03： | 1 |
| 18 | Preliminary study offlavonols in port wine grape varieties 显示文摘 | ANDRADE P B MENDES G FALCO V | 2001 | Food Chem2001，73，4： | 1 |
| 19 | Strengths and weaknesses in the determination o显示文摘 | Paeiello L Falco FC Landi C | 2013 | Enzyme Microb Technol2013，52，3： | 1 |
| 20 | Expression and distribution of notch protein members in human placenta throughout pregnancy显示文摘 | De Falco M Cobellis L Giraldi D | 2007 | Placenta2007，28，23： | 1 |
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