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| 1 | Primary liver cancer: Worldwide incidence and trends显示文摘 | F.Xavier Bosch Josepa Ribes Mireia Díaz Ramon Cléries | 2004 | Gastroenterology2004，，5： | 10 |
| 2 | 同步构绘学龄儿童脑模版和生长曲线显示文摘大脑的生长发育曲线和各年龄的标准脑模版是研究个体发育异常的必要工具.本研究构建了以一岁为间隔的儿科脑模版及相应的脑发育轨线,探究了年龄和民族在儿科脑影像研究中的影响.本研究使用了来自中美共四个站点且实验设计相同的两组纵向加速儿童脑影像队列数据,对正常发育的学龄儿童间隔五个季节进行了三次磁共振扫描.我们分别构建并比较了不同民族和年龄阶段的脑模版及发育轨线.对457名和133名正常发育的中美儿童青少年进行了总计674次和190次磁共振扫描.我们评估了使用不同民族和年龄阶段的脑模版进行配准产生的形变量,并建模大脑皮层400个不同区域体积的生长曲线.分析结果表明:构建各年龄阶段和民族特异性的脑模版对于脑生长发育曲线的绘制是必要的.脑体积在不同民族间的发育差异主要体现在结构和功能上个体差异较为明显的外侧额叶和顶叶区域,使用年龄和民族相对应的脑模版可以避免在构绘脑生长曲线时由此产生的系统偏差.本研究的所有结果及分析代码均已公开. | 董昊铭 F.Xavier Castellanos 杨宁 张喆 周荃 何叶 张蕾 徐婷 Avram J.Holmes B.T.Thomas Yeo 陈飞燕 王滨 Christian Beckmann Tonya White Olaf Sporns 邱江 冯廷勇 陈安涛 刘勋 陈旭 翁旭初 Michael P.Milham 左西年 | 2020 | Science Bulletin2020，65，22： | 4 |
| 3 | Relevant factors for the preparation of freeze-dried lactic acid bacteria显示文摘 | Ana S. Carvalho Joana Silva Peter Ho Paula Teixeira F.Xavier Malcata Paul Gibbs | 2004 | International Dairy Journal2004，，10： | 2 |
| 4 | Bifidobacterium spp. and Lactobacillus acidophilus : biological, biochemical, technological and therapeutical properties relevant for use as probiotics显示文摘 | Ana M.P. Gomes F.Xavier Malcata | 1999 | Trends in Food Science & Technology1999，，4： | 1 |
| 5 | Proteolysis of Ovine and Caprine Caseins in Solution by Enzymatic Extracts from Flowers of Cynara cardunculus显示文摘 | M.José Sousa F.Xavier Malcata | 1998 | Enzyme and Microbial Technology1998，，5： | 1 |
| 6 | Bifidobacterium spp. and Lactobacillus acidophilus : biological, biochemical, technological and therapeutical properties relevant for use as probiotics显示文摘 | Ana M.P. Gomes F.Xavier Malcata | 1999 | Trends in Food Science & Technology1999，，4： | 1 |
| 7 | Geometrical quasi-ballistic effects on thermal transport in nanostructured devices显示文摘We employ thermoreflectance thermal imaging to directly measure the steady-state two-dimensional(2D)temperature field generated by nanostructured heat sources deposited on silicon substrate with different geometrical configurations and characteristic sizes down to 400nm.The analysis of the results using Fourier's law not only breaks down as size scales down,but it alsofails to capture the impact of the geometry of the heat source.The substrate effective Fourier thermal conductivities fitted to wire-shaped and circular-shaped structures with identical characteristic lengths are found to display up to 40%mismatch.Remarkably,a hydrcxjynamic heat transport model reproduces the observed temperature fields for all device sizes and shapes using just intrinsic Si parameters,i.e.,a geometry and size-independent thermal conductivity and nonlocal length scale.The hydrodynamic model provides insight into the observed thermal response and of the contradictory Fourier predictions.We discuss the substantial Silicon hydrodynamic behavior at room temperature and contrast it to InGaAs,which shows less hydrodynamic effects due to dominant phonon-impurity scattering. | Sami Alajlouni Albert Beardo Lluc Sendra Amirkoushyar Ziabari Javier Bafaluy Juan Camacho Yi Xuan F.Xavier Alvarez Ali Shakouri | 2021 | Nano Research2021，14，4： | 0 |
| 8 | Associations between testicular development and fetal size in the pig显示文摘Background:Impaired reproductive performance is the largest contributing factor for the removal of boars from commercial systems.Intrauterine growth restricted piglets represent 25%of the total number of piglets born and have impaired reproductive performance.This study aimed to improve the understanding of temporal changes in testicular gene expression during testes development in fetuses of different size.The lightest and closest to mean litter weight(CTMLW)male Large White×Landrace littermates were collected at gestational days(GD)45,60 and 90(n=5-6 litters/GD).Results:Testes weight and testes weight as a percentage of fetal weight were not associated with fetal size at GD60 or 90.Fetal plasma testosterone was not associated with fetal size at GD90.There was no association between fetal size and seminiferous tubule area and number,number of germ or Sertoli cells per tubule.The lightest fetuses tended to have wider seminiferous tubules compared to the CTMLW fetuses at GD90(P=0.077).The testicular expression of KI67(P≤0.01)and BAX:BCL2 ratio(P=0.058)mRNAs decreased as gestation progressed.Greater SPP1 mRNA expression was observed at GD60 when compared with GD45 and 90(P≤0.05).Lower expression of DMRT1 and SPP1(P<0.01)mRNAs was observed in testes associated with the lightest fetuses compared to the CTMLW fetuses at GD90.Conclusions:These findings provide novel insights into the expression profiles of genes associated with testicular development and function.Further,these data suggest that programming of reproductive potential in IUGR boars occurs late in gestation,providing a platform for further mechanistic investigation. | Claire Stenhouse Yennifer Cortes-Araya F.Xavier Donadeu Cheryl J.Ashworth | 2022 | Journal of Animal Science and Biotechnology2022，13，5： | 0 |
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