| 3 | “Digging in the Dirt”faecal microRNAs as dietary biomarkers of host-microbe interactions显示文摘The role of diet and nutrition in maintaining a healthy lifestyle has become a central part of chronic disease prevention(1).Chronic conditions such as cancer,Inflammatory bowel disease(IBD)and obesity are more prevalent in people with poor diets(2).Food consumption is controlled by physiological systems such as the gut-microbiome and distinct neuroendocrine pathways that overlap to promote host nutritional gain resulting in people living longer healthier lives(3).A recent analysis of the global burden of disease by the World Health Organization(WHO),noted that factors associated with poor diet,including obesity and malnutrition,critically undermine health and wellbeing.They note that undernutrition,deficiencies in key nutrients and obesity have high social and economic impacts.Cardiovascular disease,cancer,diabetes,and respiratory diseases account for 77%of all diseases and are responsible for 86%of all premature deaths(4).There is an appreciation that diets that reduce or eliminate red meats and animal fats results in the reduction of many of the indicators of poor diet,such as body mass index(BMI)and levels of cholesterol in the blood. | Gerard M.Moloney John F.Cryan Gerard Clarke | 2022 | Hepatobiliary Surgery and Nutrition2022，11，2： | 0 |
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