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| 1 | 2019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。 | 刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W | 2020 | 中华高血压杂志2020,28,3: | 516 |
| 2 | 母亲妊娠期焦虑抑郁对孩子应激性心率及血压的影响显示文摘心理障碍,包括焦虑和抑郁在妊娠期间十分常见。该研究目的在于确定母亲的这些心理障碍是否会对后代的心血管反应产生影响。方法:对231名孕妇的心理状态进行评定,在其后代(n=216)7~9岁时进行视频压力反应测试。测定静息时、观看压力视频时和恢复期的心率及血压水平。 | 刘莉 叶鹏 Fan F Zou Y Tian H Zhang Y Zhang J Ma X Meng Y Yue Y Liu K Dart AM | 2015 | 中华高血压杂志2015,23,6: | 5 |
| 3 | Nomogram for predicting transmural bowel infarction in patients with acute superior mesenteric venous thrombosis显示文摘BACKGROUND The prognosis of acute mesenteric ischemia(AMI)caused by superior mesenteric venous thrombosis(SMVT)remains undetermined and early detection of transmural bowel infarction(TBI)is crucial.The predisposition to develop TBI is of clinical concern,which can lead to fatal sepsis with hemodynamic instability and multi-organ failure.Early resection of necrotic bowel could improve the prognosis of AMI,however,accurate prediction of TBI remains a challenge for clinicians.When determining the eligibility for explorative laparotomy,the underlying risk factors for bowel infarction should be fully evaluated.AIM To develop and externally validate a nomogram for prediction of TBI in patients with acute SMVT.METHODS Consecutive data from 207 acute SMVT patients at the Wuhan Tongji Hospital and 89 patients at the Guangzhou Nanfang Hospital between July 2005 and December 2018 were included in this study.They were grouped as training and external validation cohort.The 207 cases(training cohort)from Tongji Hospital were divided into TBI and reversible intestinal ischemia groups based on the final therapeutic outcomes.Univariate and multivariate logistic regression analyses were conducted to identify independent risk factors for TBI using the training data,and a nomogram was subsequently developed.The performance of the nomogram was evaluated with respect to discrimination,calibration,and clinical usefulness in the training and external validation cohort.RESULTS Univariate and multivariate logistic regression analyses identified the following independent prognostic factors associated with TBI in the training cohort:The decreased bowel wall enhancement(OR=6.37,P<0.001),rebound tenderness(OR=7.14,P<0.001),serum lactate levels>2 mmol/L(OR=3.14,P=0.009)and previous history of deep venous thrombosis(OR=6.37,P<0.001).Incorporating these four factors,the nomogram achieved good calibration in the training set[area under the receiver operator characteristic curve(AUC)0.860;95%CI:0.771-0.925]and the external validation set(AUC 0.851;95%CI:0.796-0.897).The positive and negative predictive values(95%CIs)of the nomogram were calculated,resulting in positive predictive values of 54.55%(40.07%-68.29%)and 53.85%(43.66%-63.72%)and negative predictive values of 93.33%(82.14%-97.71%)and 92.24%(85.91%-95.86%)for the training and validation cohorts,respectively.Based on the nomogram,patients who had a Nomo-score of more than 90 were considered to have high risk for TBI.Decision curve analysis indicated that the nomogram was clinically useful.CONCLUSION The nomogram achieved an optimal prediction of TBI in patients with AMI.Using the model,the risk for an individual patient inclined to TBI can be assessed,thus providing a rational therapeutic choice. | Meng Jiang Chang-Li Li Chun-Qiu Pan Wen-Zhi Lv Yu-Fei Ren Xin-Wu Cui Christoph F Dietrich | 2020 | World Journal of Gastroenterology2020,26,26: | 4 |
| 4 | Comparison of HER-2/neu,ER and PCNA expression in premenopausal and postmenopausal patients with breast carcinoma显示文摘 | Zheng W Zheng J Ma L Meng F Huang L Ma D | 2005 | 第二军医大学学报2005,26,8: | 4 |
| 5 | Interobserver agreement for contrast-enhanced ultrasound of liver imaging reporting and data system:A systematic review and metaanalysis显示文摘BACKGROUND Hepatocellular carcinoma is the most common primary liver malignancy.From the results of previous studies,Liver Imaging Reporting and Data System(LIRADS)on contrast-enhanced ultrasound(CEUS)has shown satisfactory diagnostic value.However,a unified conclusion on the interobserver stability of this innovative ultrasound imaging has not been determined.The present metaanalysis examined the interobserver agreement of CEUS LI-RADS to provide some reference for subsequent related research.AIM To evaluate the interobserver agreement of LI-RADS on CEUS and analyze the sources of heterogeneity between studies.METHODS Relevant papers on the subject of interobserver agreement on CEUS LI-RADS published before March 1,2020 in China and other countries were analyzed.The studies were filtered,and the diagnostic criteria were evaluated.The selected references were analyzed using the“meta”and“metafor”packages of R software version 3.6.2.RESULTS Eight studies were ultimately included in the present analysis.Meta-analysis results revealed that the summary Kappa value of included studies was 0.76[95%confidence interval,0.67-0.83],which shows substantial agreement.Higgins I2 statistics also confirmed the substantial heterogeneity(I2=91.30%,95%confidence interval,85.3%-94.9%,P<0.01).Meta-regression identified the variables,including the method of patient enrollment,method of consistency testing,and patient race,which explained the substantial study heterogeneity.CONCLUSION CEUS LI-RADS demonstrated overall substantial interobserver agreement,but heterogeneous results between studies were also obvious.Further clinical investigations should consider a modified recommendation about the experimental design. | Jun Li Ming Chen Zi-Jing Wang Shu-Gang Li Meng Jiang Long Shi Chun-Li Cao Tian Sang Xin-Wu Cui Christoph F Dietrich | 2020 | World Journal of Clinical Cases2020,8,22: | 2 |
| 6 | A SAXS study on microstructural change in Al-Zn-Mg alloy during retrogression and reaging 显示文摘 | Meng Z F Wang Y M | 1990 | Scripta Metall1990,24,7: | 2 |
| 7 | Calpain activity in the rat brain after transient forebrain ischemia 显示文摘 | NEUMAR R W MENG F H MILLS A M | 2001 | Exp Neurol2001,170,1: | 1 |
| 8 | Construction and characterization of a single-chain antibody fragment derived from thymus of a patient with myasthenia gravis 显示文摘 | Meng F Stassen M H Schillberg S | 2002 | Autoimmunity2002,35,2: | 1 |
| 9 | Atmospheric deposition and hydro geologic flow of nitrogen in northern Florida Watersheds显示文摘 | WINCHESTER J W ESCALONA L MENG F J | 1995 | Geochimica et Cosmochimica Acta1995,59,11: | 1 |
| 10 | A comprehensive study on membrane fouling in submerged membrane biore-actors operated under different aeration intensities 显示文摘 | MENG F YANG F SHI B | 2008 | Separation and Purification Technology2008,59,1: | 1 |
| 11 | Application of CVD nanocrystalline diamond films to cemented carbide drills 显示文摘 | Meng X M Tang W Z Hei L F | 2008 | Int J Refractory Metals and Hard Mater2008,26,5: | 1 |
| 12 | Thermodynamic assessment of the Ag-Yb system显示文摘 | ZHANG L G MENG F G LIU H S LILT L B JIN Z P | 2008 | J Alloys and Compounds2008,452,: | 1 |
| 13 | Chitosan and alginate polyelectrolyte complex membranes and their properties for wound dressing application显示文摘 | Meng X Tian F Yang J | 2010 | J Mater Sci-Mater M2010,21,5: | 1 |
| 14 | Gas sensing behavior of a single tin dioxide sensor under dynamic temperature modulation显示文摘 | Huang X Meng F Pi Z | 2004 | Sensors Actuators2004,99,23: | 1 |
| 15 | Effective therapy of metastatic ovarian cancer with an oncolytic herpes simplex vinus incorporating two membrane fusion meelumisms显示文摘 | NAKAMORI M FU X MENG F | 2003 | Clin Can Res2003,9,4: | 1 |
| 16 | Photostability of Novel Copolymers Functionalized with Laser Dyes Based on Modified Rhodamine 6G and 1,8-naphthalimide 显示文摘 | Yang S Meng F Tian H | 2002 | European Polymer Journal2002,38,5: | 1 |
| 17 | MieroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatoeel- lular cancer显示文摘 | Meng F Henson R Wehbe-Janek H | 2007 | castroenterology2007,133,2: | 1 |
| 18 | The structural and magnetic properties of Mn2 xFexNiGa Heusler alloys显示文摘 | LUO H Z MENG F B FENG Z Q LI Y X ZHU W WU G H ZHU X X JIANG C B XU H B | 2010 | J Appl Phys2010,107,01: | 1 |
| 19 | Research on database显示文摘 | LI Y K MENG X F ZHANG X Y | | 0,,08: | 1 |
| 20 | Improved model for mercury emission, transport and deposition显示文摘 | Gbor P K Wen D Y Meng F | 2006 | Atmospheric Environment2006,40,5: | 1 |