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| 1 | Diffusion-weighted magnetic resonance imaging to predict response of hepatocellular carcinoma to chemoembolization显示文摘AIM: To investigate whether intra-procedural diffusion- weighted magnetic resonance imaging can predict response of hepatocellular carcinoma (HCC) during trans- catheter arterial chemoembolization (TACE). METHODS: Sixteen patients (15 male), aged 59 ±11 years (range: 42-81 years) underwent a total of 21 separate treatments for unresectable HCC in a hybrid magnetic resonance/interventional radiology suite. Ana- tomical imaging and diffusion-weighted imaging (b = 0, 500 s/mm2) were performed on a 1.5-T unit. Tumor enhancement and apparent diffusion coefficient (ADC, mm2/s) values were assessed immediately before and at 1 and 3 mo after TACE. We calculated the percent change (PC) in ADC values at all time points. We compared follow-up ADC values to baseline values using a paired t test (α = 0.05). RESULTS: The intra-procedural sensitivity, specificity, and positive and negative predictive values (%) for detecting a complete or partial 1-mo tumor response using ADC PC thresholds of ±5%, ±10%, and ±15% were 77, 67, 91, and 40; 54, 67, 88, and 25; and 46, 100, 100, and 30, respectively. There was no clear predictive value for the 3-mo follow-up. Compared to baseline, the immediate post-procedure and 1-mo mean ADC values both increased; the latter obtaining statistical significance (1.48 ± 0.29 mm2/s vs 1.65 ± 0.35 × 10-3 mm2/s, P < 0.014). CONCLUSION: Intra-procedural ADC changes of > 15% predicted 1-mo anatomical HCC response with the greatest accuracy, and can provide valuable feedback at the time of TACE. | Johnathan C Chung Neel K Naik Robert J Lewandowski Mary F Mulcahy Laura M Kulik Kent T Sato Robert K Ryu Riad Salem Andrew C Larson Reed A Omary | 2010 | World Journal of Gastroenterology2010，16，25： | 13 |
| 2 | Gastroenteropancreatic neuroendocrine tumours显示文摘 | Irvin M Modlin Kjell Oberg Daniel C Chung Robert T Jensen Wouter W de Herder Rajesh V Thakker Martyn Caplin Gianfranco Delle Fave Greg A Kaltsas Eric P Krenning Steven F Moss Ola Nilsson Guido Rindi Ramon Salazar Philippe Ruszniewski Anders Sundin | 2008 | Lancet Oncology2008，，1： | 8 |
| 3 | Receptor activator of NF-κB Ligand (RANKL) expression is associated with epithelial to mesenchymal transition in human prostate cancer cells显示文摘 | Valerie A Odero-Marah Ruoxiang Wang Gina Chu Majd Zayzafoon Jianchun Xu Chunmeng Shi Fray F Marshall Haiyen E Zhau Leland WK Chung | 2008 | Cell Research2008，18，8： | 6 |
| 4 | Productivity and Undesirable Outputs: A Directional Distance Function Approach显示文摘 | Y.H. Chung R. F?re S. Grosskopf | 1997 | Journal of Environmental Management1997，，3： | 5 |
| 5 | Productivity and Undesirable Outputs: A Directional Distance Function Approach显示文摘 | Y.H. Chung R. F?re S. Grosskopf | 1997 | Journal of Environmental Management1997，，3： | 2 |
| 6 | Excited - state properties of dioxorhenium(V) generation and reactivity of dioxorhenium(Ⅵ) 显示文摘 | Che C M Chung W C Lai T F | 1989 | Inorg Chem1989，28，： | 1 |
| 7 | Multimodal analgesia for posteroprative pain control 显示文摘 | Jin F Chung F | 2001 | J Clin Anesth2001，13，： | 1 |
| 8 | Postoperation symptoms 24 hours after ambulatory anesthesia显示文摘 | Un V Su J | 1996 | Can J Anaesth1996，43，11： | 1 |
| 9 | Angiotensin II induces connective tissue growth factor and collagen I expression via transforming growth factor-beta-dependent and -independent Smad pathways: the role of Smad3 显示文摘 | Yang F Chung AC Huang XR | 2009 | Hypertension2009，54，4： | 1 |
| 10 | Minimizing perioperative adverse event s in the elderly显示文摘 | Jin F Chung F | 2001 | Br J Anaesth2001，87，4： | 1 |
| 11 | Postoperative delirium in the elderly 显示文摘 | Parikh SS Chung F | 1995 | Anesth Analg1995，80，6： | 1 |
| 12 | Color image segmentation using fuzzy C-mean and eigenspace projections显示文摘 | YANG J F HAO S S CHUNG P C | 2002 | Signal Prooeming2002，82，3： | 1 |
| 13 | Three Dimensional Simulation of the Edge Rolling Process by the Explicit FiniteElement Method显示文摘 | Chung W K Choi S K Thomson P F | 1993 | Journal of Materials Processing Technology1993，38，： | 1 |
| 14 | Optical orthogonal codes:design,analysis,and applications显示文摘 | CHUNG F R K SALEHI C J A | 1989 | IEEE Trans Inform Theory1989，35，5： | 1 |
| 15 | Gelation of surimi by high hydrostatic pressure显示文摘 | Chung Y C Gebrehiwot A Farkas D F Morrissey M T | 1994 | J Food Sci1994，59，52： | 1 |
| 16 | Postoperative delirium in the elderly显示文摘 | Parikh SS Chung F | 1995 | Anesth Analg1995，80，6： | 1 |
| 17 | The nature and timing of crustal thickening in Southern Tibet:Geochemical and zircon Hf isotopic constraints from postcollisional adakites显示文摘 | Chung S L Chu M F Ji J | 2009 | Tectonophysics2009，477，1： | 1 |
| 18 | Fuzzy kernel hyperball perceptron显示文摘 | Chung F L Wang S T Deng Z H | | 0，，01： | 1 |
| 19 | Lymphocytes in the development of lung inflammation : a role for regulatory CD4 + T cells in indirect pulmonary lung injury 显示文摘 | Venet F Chung CS Huang X | 2009 | J Immunol2009，183，5： | 1 |
| 20 | Internal transcribed spacer sequence analysis of Angelica from different habitats 显示文摘 | HAO H C CHANG J Y CHUNG F Y | 2012 | Genomic Medicine Biomarkers and Health Sciences2012，4，1： | 1 |
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